2002.9-2007.7，中科院生物物理所，博士

1998.9-2002.7，厦门大学生命科学院，学士

2015.1至今，浙江大学转化医学研究院，副教授

2008.3-2014.12，密歇根大学放射肿瘤学系，博士后

核糖体蛋白除了具有最基本的蛋白合成功能外，还参与细胞存活、细胞分化、细胞凋亡、维持基因组稳定性等生理过程的调控。核糖体蛋白功能异常与血液、代谢方面的疾病以及癌症发生和发展密切相关。我们运用细胞生物学、生化和分子生物学、组织病理学和转基因小鼠肿瘤模型等手段研究核糖体蛋白RPS27L在肿瘤发生和发展中的作用和机理及其临床应用价值，为RPS27L成为癌症诊断或预后的分子指标提供理论依据。

1. Xiong XF#, Zhao YC#, Tang F, Wei D, Thomas D, Wang X, Liu Y, Zheng P, Sun Y*. Ribosomal protein S27-like is a physiological regulator of p53 that suppresses genomic instability and tumorigenesis. eLife 2014, 3: e02236. (#equal contribution) Recommended by Faculty of 1000

2. Xiong XF, Zhao YC, He HB, Sun Y*. Ribosomal protein S27-like and S27 interplay with p53-MDM2 axis as a target, a substrate and a regulator. Oncogene 2011, 30(15): 1798-811.

3. Xiong XF, Li H, Cao EH*. PIG11 protein binds to DNA in sequence-independent  manner in vitro. Biochemical and Biophysical Research Communications 2007, 358: 29-34.

4. Zhao YC, Xiong XF, Jia LJ, Sun Y*. Targeting Cullin-RING ligases by MLN4924 induces autophagy by modulating the HIF1-REDD1-TSC1-mTORC1-DEPTOR axis. Cell Death & Disease 2012, 3: e386.

5. Zhao YC, Xiong XF, Sun Y*. DEPTOR, an mTOR inhibitor, is a physiological substrate of SCFβTrCP E3 ubiquitin ligase and regulates survival and autophagy. Molecular Cell 2011, 44(2): 304-16.