Profile

EDUCATION
1996-1998, Freiburg University, Freiburg i. Br. Germany, MD Degree in Medicine.
1980-1988, Nanjing Railway Medical College, Nanjing, China, MS Degree in Pathology; BA Degree in Medicine

PROFESSIONAL EXPERIENCE
Jan.2005 to present  School of Medicine, Zhejiang University, Hangzhou, China
Associate professor, Department of Pathology
-Responsible for three research projects mainly including tumor-stroma interaction in colorectal carcinoma
-Taught two or more courses of Pathology each semester to both undergraduate and graduate students
-Worked on the clinical diagnosis of surgical pathology and renal pathology
Jun.1998-Dec. 2004  Medical College, Southeast University, Nanjing, China
Associate professor & Director, Department of Pathology
-Responsible for three research projects mainly including experimental renal pathology and the intercellular induction of apoptosis in tumor
-Taught two or more courses of Pathology each semester to both undergraduate and graduate students
-Directed the work of research assistants and technicians on the projects
-Worked on the clinical diagnosis of surgical pathology and renal pathology
Feb.1996-Jun.1998  Freiburg University, Freiburg, Germany
Visiting scholar, Department of Virology and Institute of Pathology
-Completed doctoral dissertation, scored ”magna cum laude”
-Participated in the research of the intercellular induction of apoptosis in tumor, including establishing spheroid cell culture system, detecting apoptosis in the system
Jan.1991-Oct.1995  Nanjing Railway Medical College, Nanjing , China
Instructor, Department of Pathology
-Responsible for a research project including production of the model of Heymann’s nephritis in rats, research of its pathogenesis and treatment with some drugs
-Taught Pathology to undergraduates and adult learners
-Worked on the clinical diagnosis of surgical pathology, general pathology and renal pathology
Jul.1988-Dec.1991   Nanjing Railway Medical College, Nanjing, China
Assistant Instructor, Department of Pathology
-Taught Pathology to undergraduates
-Participating in the research of rats bladder carcinoma
-Worked on the clinical diagnosis of surgical pathology and renal pathology

RESEARCH INTERESTS
Development and progression of cancer involves not just the tumor cells themselves, but also other “host” cells in the tumor microenvironment. The goal of our research is to identify the molecular mechanism of tumor-stroma interaction in colorectal carcinoma by means of biological, chemical and pathological techniques and to provide a better understanding of tumorigenesis and useful targets for cancer diagnosis, prognosis and treatment.

ONGOING PROJECTS
1.Natural Science Foundation of China, 30870971
2.Natural Science Foundation of Zhejiang, Y207308

SELECTED PUBLICATIONS( * Corresponding author)
1.Bai X, Deng H*. Research progress on relationship between transcription factor Sp1 and tumor. Journal of Zhejiang University (Medical Sciences),  2010, 39(2):215-20.
2.Shen XJ, Zhang YW, Deng H*, Chen LL, Chen PS. Fibroblasts-colorectal cancer cells interaction induces expression of IGFBP7. Journal of Zhejiang University (Medical Sciences), 2009, 38(2): 151-157.
3.Chen LL, Deng H*, Li Q, Chen PS. High glucose and tea polyphenols on expression of matrix metalloproteinase-2 and extracellular matrix metalloproteinase in human umbilical vein endothelial cells. Chinese Journal of Pathology, 2009, 38(8):532-536.
4.Shen XJ, Deng H*. Regulation of transcription factor activator protein 1 cell signaling in tumor-stroma interaction. Chinese Journal of Pathology, 2009, 38(3):211-213.
5.Ma Y, Lv B, Ruan W, Wang H, Lin J, Hu H, Deng H, Huang Q, Lai M*. Tumor suppressor gene insulin-like growth factor binding  protein-related protein 1 (IGFBP-rP1) induces senescence-like growth  arrest in colorectal cancer cells, Experimental and molecular pathology, 2008,85(2):141-5.
6.Wu J, Deng H*. Interaction of cancer-associated fibroblasts and tumor cells in carcinogenesis. Journal of Zhejiang University (Medical Sciences), 2008, 37(2): 212-217.
7.Ruan W, Xu E, Xu F, Ma Y, Deng H, Huang Q, Lv B, Hu H, Lin J, Cui J, Di M, Dong J, Lai M*. IGFBP-rP1 plays a potential tumor suppressor role in colorectal carcinogenesis. Cancer biology and therapy, 2007, 6(3):354-9.
8.Zheng YW, Deng H*, Chen PS, Chen LL. Increased expression of extracellular matrix metalloproteinase inducer through interaction between fibroblasts and colonic cancer cells. Chinese Journal of Pathology, 2007, 36(11):764-767.
9.Zhao ZM, Deng H*. Roles of gap junctions in tumorigenesis. Chinese Journal of Pathology, 2007, 36(3):203-205.
10.Deng H*, Li HL, Wang K, Zeng Y, Liu BC. Effect of glomerular intercellular interaction under high glucose concentration on production of ROS and TGF1 in co-cultured ECV304 cells and intervention with tea polyphenols. Chinese Journal of Pathophysiology, 2006, 22(2):326-329.

SOCIETY MEMBERSHIPS
Member of Chinese Medical Association
Member of Pathologist Branch of Chinese Medical Doctor Association

HONORS AND AWARDS
2008, Outstanding Teaching Staff Award, Zhejiang University, China
2008, Outstanding Teaching Staff Award, Medical College of Zhejiang University, China
1999, Outstanding Teaching Staff Award, Nanjing Railway Medical College, China
1995, Volkswagen Scholarship, Germany