Profile

Dr. Feng is employed as Professor/PhD supervisor at Center for Infection & Immunity, Department of Medical Microbiology & Parasitology, Zhejiang University School of Medicine. Before his joining Zhejiang University, Dr. Feng acted as a Research Scientist at the University of Illinois at Urbana Champaign (UIUC). Dr. Feng’s research is focused on 1) metabolism and regulation of two important fatty acid-derived vitamins (biotin/lipoic acid) in foodborne bacterial pathogens (such as E. coli and Vibrio cholerae) and 2) probing molecular mechanism of the zoonotic pathogen Streptococcus suis infection. So far, Dr. Feng has already been authored in nearly 60 papers published in international peer-reviewed journals, and has obtained important academic achievements.Education Experience2004.9--2007.6, Ph.D., Molecular Immunology and Molecular Virology, Institute of Microbiology/Graduate School in Chinese Academy of Sciences (CAS), Beijing, China 2001.9--2004.7, M.Sc., Microbiology, College of Life Science & Technology, Guangxi University, Nanning, China 1997.9--2001.7, B.Sc., Biotechnology, College of Life Science & Technology, Northwest University of Light Industry, Xianyang, ChinaResearch Experiences2014.3 -- Professor Center for Infection & Immunity, Department of Medical Microbiology & Parasitology, Zhejiang University School of Medicine2013.1-- 2014.3 (Research Scientist)In Department of Microbiology, University of Illinois at Urbana-Champaign, my research is centering on metabolism and regulation of bacterial fatty acids and its derivatives biotin & lipoic acids2008.1-- 2013.1 (Post-doc research associate)In the School of Molecular and Cellular Biology, University of Illinois at Urbana-Champaign, my research is centering on metabolism and regulation of bacterial fatty acids and its derivative biotin.2007.6-- 2008.1 (Post-doc associate)In the Institute of Microbiology, Chinese Academy of Sciences, I focused on study of Streptococcus suis genetics and PRRS virus infectious clone.2004.9-- 2007.6 (Ph. D) In the Institute of Microbiology, Chinese Academy of Sciences (IMCAS), my research exploration was concentrating on structural and molecular pathogenesis of highly infectious agents including Streptococcus suis and avian influenza virus (e.g., H5N1).2001.9-- 2004.7 (M. Sc.)During the period of MSc. study in Guangxi University, I was aiming to investigation of the molecular virology of hypovirus and molecular biology of filamentous fungi, including the rice blast fungus Magnaporthe oryzae and the chestnut blight fungus, Cryphonectria parasitica.Main publications1. Xiaolu Shi …… Youjun Feng*, Loss of 89K pathogenicity island in epidemic Streptococcus suis, China, Emerg Infect Dis. 2016, Accepted *通讯作者2. Huimin Zhang …… Youjun Feng*, Deciphering a unique biotin scavenging pathway with redundant genes in the probiotic bacterium Lactococcus lactis, Sci Rep. 2016, Accepted *通讯作者3. Huiyan Ye …… Youjun Feng*, Functional definition of BirA suggests a biotin utilization pathway in the zoonotic pathogen Streptococcus suisSci Rep. 2016, Under Revision *通讯作者4. Huiyan Ye …… Youjun Feng*, Diversified mcr-1-harbouring plasmid reservoirs confer resistance to colistin in human gut microbiota, mBio, 2016 Apr 5; 7(2). pii: e00177-16. doi: 10.1128/mBio.00177-16. *通讯作者5. Huimin Zhang, Swaminath Srinivas, Defeng Li, Youjun Feng*, Origin, dissemination and entry of the pandemic Zika viruses, Science Bulletin 2016, Accepted *通讯作者6. Huimin Zhang, Christopher H Seward, Zuowei Wu, Huiyan Ye, Youjun Feng*, Genomic insights into the ESBL and MCR-1-producing ST648 Escherichia coli with multi-drug resistance, Science Bulletin 2016, Accepted *通讯作者7. Min Cao…… Youjun Feng*, Determination of Scrub typhus suggests a new epidemic focus in the Anhui province of China, Sci Rep. 2016 Feb 10; 6: 20737. doi: 10.1038/srep20737. *通讯作者8. Rongsui Gao, Jingxia Lin, Huimin Zhang, Youjun Feng*, Transcriptional repression of the VC2105 by the Vibrio FadR suggests a new auxiliary member of the fad regulon, Appl Environ Microbiol. 2016 May, 82 (9): 2819-2832. *通讯作者9. Deng C …… Youjun Feng*, Xianbo Deng*, Deoxynivalenol inhibits proliferation and induces apoptosis in human umbilical vein endothelial cells, Environ Toxicol Pharmacol. 2016 Mar 26; 43: 232-241. doi: 10.1016/j.etap.2016.02.002. [Epub ahead of print]. *通讯作者201510. Youjun Feng, Chui-Yoke Chin, Vandana Chakravartty, Rongsui Gao, David S. Weiss, John E. Cronan*, The atypical occurrence of two biotin protein ligases in Francisella is due to distinct roles in virulence and biotin metabolism, mBio, 2015 Jun 9;6(3). pii: e00591-15. doi: 10.1128/mBio.00591-15.11. Huimin Zhang, Dmitry A. Ravcheev, Dan Hu, Fengyu Zhang, Xiufang Gong, Lina Hao, Min Cao, Dmitry A. Rodionov, Changjun Wang , Youjun Feng*, Two novel regulators of N- acetyl- galactosamine utilization pathway and distinct roles in bacterial infections, Microbiology Open, 2015,Dec; 4(6): 983-1000. doi: 10.1002/mbo3.307., *通讯作者12. Youjun Feng*, Ritesh Kumar, Dmitry A. Ravcheev, Huimin Zhang，Paracoccus denitrificans possesses two BioR homologues having a role in regulation of biotin metabolism, Microbiology Open, 2015, Aug; 4(4): 644-59. doi: 10.1002/mbo3.270. *通讯作者13. Huimin Zhang, Beiwen Zheng, Rongsui Gao, Youjun Feng*, Binding of Shewanella FadR to the fabA fatty acid biosynthetic gene: Implications for contraction of the fad regulon，Protein & Cell, 2015, Sep; 6(9):667-79. doi: 10.1007/s13238-015-0172-2, *通讯作者14. Yi Sun, Henghui Wang, Xiuyu Lou, Haiyan Mao, Yong Yan, Enfu Chen, Xinying Wang, Zhen Li, Jian Gao, Xiaofei Fu, Zhongwen Chen, Youjun Feng, Zhiping Chen, Yanjun Zhang, Living poultry markets in rural area: Human infection with H7N9 virus re-emerges in Zhejiang Province, China, in winter 2014, Journal of Clinical Virology, 2015, Sep;70:16-22. doi: 10.1016/j.jcv.2015.06.092. 15. Dan Hu, Lina Hao, Jinhai Zhang, Pingping Yao, Qi Zhang, Heng Lv, Xiufang Gong, Xiuzhen Pan, Min Cao, Jin Zhu, Yun Zhang, Youjun Feng, Changjun Wang, Development of reverse transcription loop-mediated isothermal amplification assays to detect Hantaan virus and Seoul virus, Journal of Virological Methods, 2015, 221: 68-73. 16. Huimin Zhang, Qixia Luo, Haichun Gao*, Youjun Feng*, A new regulatory mechanism for bacterial lipoic acid synthesis, Microbiology Open, 2015, Jan 22. doi: 10.1002/mbo3.237 *通讯作者17. Li M, Shao ZQ, Guo Y, Wang L, Hou T, Hu D, Zheng F, Tang J, Wang C, Youjun Feng, Gao J, Pan X. The type II histidine triad protein HtpsC is a novel adhesion with the involvement of Streptococcus suis virulence, Virulence. 2015; 6 (6): 631-41.