Profile

Academic Appointments
Member of ILTS
Member of the Chinese Chapter of International Hepato-Pancreto-Biliary Association
Fellowship of American College of Surgeons, FACS
Member of Surgery Chapter of Chinese Medical Association
Secretary and Member of the Organ Transplantation Group, Surgery Chapter of Chinese Medical Association
Young member of the Organ Transplantation Chapter of Chinese Medical Association
Vice Chairmen and Secretary of the Organ Transplantation Chapter of the Medical Association of Zhejiang Province, China
Vice Chairmen of the General Surgery Chapter of the Integrated Traditional Chinese and Western Medical Association of Zhejiang Province, China
Member of the Surgery Chapter of the Medical Association of Zhejiang Province, China
Member of the 5th Hepatobiliary & Pancreatic Tumor Speciality Committee of the Anti-cancer Association of Zhejiang Province, China
Member of 7th Standing Council of the Medical Association of Zhejiang Province, China
Member of the Doctor Association of Zhejiang Province, China
Member of the Professor Committee of Zhejiang University School of Medicine

Special Appointments
Editorial Boards: HBPD INT, Current opinion in Organ Transplantation (Chinese Version), Chinese Journal of Surgery, Chinese Journal of Digestive Surgery, Chinese Journal of Practical Surgery, Chinese Journal of Transplantation, Zhejiang Medical Journal, Journal of Hepatopancreatobiliary Surgery, International Journal of Surgery, Chinese Journal of Bases and Clinics in General Surgery, Journal of Surgery Concepts & Practice, Chinese Journal of Experimental Surgery, Chinese Archive of General Surgery, etc.
Reviewers: Cell Biology International Chinese Medical Journal, National Medical Journal of China, Acta Academiae Medicinae Sinicae,

Education and Working Experience
1989.9～1992.7   Master, Zhejiang University School of Medicine    
1992.7～present   Department of Surgery, The First Affiliated Hospital, School of Medicine, Zhejiang University
1998.3～1998.5   GB Ongoing Fellow, Division of HBP and Liver transplant Surgery, Queen Mary Hospital, Hongkong University, Hongkong
1999.9～2002.7   Ph.D, Zhejiang University School of Medicine
2000.10～2001.10  Research Assistant, Division of HBP and Liver transplant Surgery, Queen Mary Hospital, Hongkong University,Hongkong
2004.12～present  Ph.D supervisor, Zhejiang University

Research funding, more than 50 grants including
1．Clinical and Basic research in liver transplantation, National Natural Science Funds for Distinguished Young Scholar
2．The regulative role of HSC to the hepatic sinusoidal in small-for-size liver transplantation, supported by National Natural Science Foundation of China
3．CD4+CD25+ regulatory T cells in acute graft-versus-host disease following liver transplantation, supported by National Natural Science Foundation of China
4．Liver transplantation for hepatobiliary&pancreatic malignant tumor, supported by Key Grant of Administration of Science and Technology of Zhejiang Provience, China
5．MCP-1 in the hepatic veno-occlusive disease induced by Gymura segetum, supported by Key Grant of Administration of Traditional Chinese Medicine of Zhejiang Provience, China

Publications
Over 150 journal articles on hepatobiliary surgery; 8 book chapters.
Selected publications:
1. The different modality effects of Rapamycin and FK506 on Acute Graft-Versus-Host Disease in the Rat with Liver Transplantation. Liver Transpl. 2010 Mar;16(3):357-63.  
2. Sinusoidal microcirculatory changes after small-for-size liver transplantation in rats. Transplant Int. 2010 Feb 19. [Epub ahead of print]  
3. Sphincter of Oddi laxity: An important factor in hepatolithiasis. World J Gastroenterol. 2010 February 28; 16(8): -000  
4. Changes of sphingolipids profiles after ischemia-reperfusion injury in the rat liver. Chin Med J (Engl). 2009 Dec;122(24):3025-31.
5. Regulatory T Cells Contribute to the Immunoregulatory Effect on Graft Versus Host Reaction after Liver Transplantation in Donor-Dominant One Way MHC Matching Rats. Transplant Immunology. 2009 Mar 20(4):232-237.  
6. Metabonomic Profiles of the Rats with Acute Liver Rejection in Early Phase. Omics-A Journal of Integrative Biology. 2009 13(2):81-91.
7. Establishment of an Acute Graft versus Host Disease Model Following Liver Transplantation in Donor-Dominant One-Way MHC Matching Rats. Transplant Proc, 2009 Jun;41(5):1914-1920.  
8. Therapeutic Potential and Related Signal Pathway of Adipose-Derived Stem Cell Transplantation for Rat Liver Injury.  Hepatol Res. 2009 Aug;39(8):822-32.  
9. Intraoperative blood salvage and leukocyte depletion during liver transplantation with bacterial contamination. Clin Transplant. 2009 Sep 24. [Epub ahead of print]  
10. Resuscitation With Hydroxyethyl Starch Solution Prevents Bone Marrow Mononuclear Apoptosis in a Rat Trauma-Hemorrhagic Shock Model. J Trauma. 2010;68:655-661.
11. Allicin, a major component of garlic, inhibits apoptosis of vital organ in Trauma/Hemorrhagic shock rats. Crit Care Med. 2008 Dec, 36(12):3226-3232.  
12. Intraoperative blood salvage during liver transplantation for hepatocellular carcinoma: efficiency of leukocyte depletion filter to eliminate tumor cells. Transplantation, 2008;85(6):863-9.
13. Resuscitation with hydroxyl starch solution prevents CD4+ T lymphocytes apoptosis and modulates the balance of Th1 and Th2 responses in the rat with traumatic hemorrhagic shock. Shock. 2008 Dec 30(6):692-698.
14. Protective effect of Glutathione against liver warm ischemia-reperfusion injury in rat model is associated with regulation of P-selectin and neutrophil infiltration. Anat Rec (Hoboken). 2008 Aug 291(8):1016-1022.
15. Pancreatic fistula after pancreaticoduodenectomy: diagnosed according to International Study Group Pancreatic Fistula (ISGPF) definition. Pancreatology. 2007;7(4):325-31.  
16. Early postoperative hemorrhage requiring urgent surgical reintervention after orthotopic liver transplantation. Transplant Proc. 2007 Jun;39(5):1549-53.  
17. Mucocele formation of cystic bile duct remnant after orthotopic liver transplantation. Chin Med J (Engl). 2007 Feb 5;120(3):254-6.  
18. Elevation of Intact Parathyroid Hormone Level Is the Risk Factor for Low Bone Mineral Density in the Pretransplant Patients for Liver Diseases. Transplant Proc 2007, 12 Dec; 39(10):3182-3185.  
19. Pure red cell aplasia due to parvovirus B19 infection after liver transplantation: a case report and review of the literature. World J Gastroenterol. 2007 Apr 7;13(13):2007-10. Review.  
20. Long-term results of laparoscopic fenestration for patients with congenital liver cysts. Hepatobiliary Pancreat Dis Int 2007, Dec; 6(6):600-603.
21. Prevention of hepatitis B recurrence after liver transplantation using lamivudine or lamivudine combined with hepatitis B Immunoglobulin prophylaxis. Liver Transpl. 2006 Feb;12(2):253-8. 22. The outcome of patients with ABO-incompatible liver in emergency liver transplantation. Hepatology. 2006 Vol 44(4) Suppl. 1: 123A.
23. Prevalence and predominant factor of low bone mineral density among patients awaiting liver transplantation. Hepatology. 2006 Vol 44(4) Suppl. 1: 123A. (Meeting Abstract)  
24. Activation pattern of mitogen-activated protein kinases in early phase of different size liver isografts in rats. Liver Transpl, 2005 Dec;11(12):1527-32.  
25. Distinct intragraft response pattern in relation to graft size in liver transplantation. Transplantation. 2003, 15;75(5):673-8.  

Honors and Awards
Second class National Science and Technology Progress Award, 2008, rank 3
Young expert with outstanding contribution awarded by Chinese Ministry of Health, 2006
First Prize of Science and Technology Award of Zhejiang Province, China, 2005, Rank 2
The 8th Young Peoples’ Science Award of Zhejiang Province, China, 2005
First Prize of Science and Technology Innovation Award in the field of medicine and health of Zhejiang Province, China, 2005, Rank 2
The 3rd prize of Chinese Medical Science and Technology Award, 2005
First Prize of Science and Technology Innovation Award in the field of medicine and health of Zhejiang Province, China, 2004, Rank 2
First Prize of Science and Technology Advanced Award of Zhejiang Province, China, 2000, Rank 3
First Prize awarded by Bureau of health of Zhejiang Province, China, 2000, Rank 3