Profile

Name: Ya-fei Mao
Sex: Female
Academic degree: Master
Professional Title: Associate professor of Medical Microbiology and parasitology
Phone: 0086-571-88208294 (Office), 13588163521 (Mobile)
Fax: 0086-571-88208294
E-mail: myf@zju.edu.cn


一、CHIEF EDUCATION AND EXPERIENCE
2004-2010: College of Medical Science, Zhejiang University, Associated professor
1998-2004: College of Medical Science, Zhejiang University, Lecturer
1993-1998: Department of parasitology, Zhejiang Medical University,. Teaching assistant

二、RESEARCH INTERESTS
Development of genetically engineering vaccine of Helicobacter pylori and drugs based on the enterotoxin of Staphylococcus aureus.
三、MAJOR PROJECTS
One grants from technology plan project of Zhejiang province. Participating 3 Chinese National Natural Science Fundation

四、RECENT SELECTED PUBLICATIONS
1 Jie Yan, Li-Li Chen, Yi-Hui Luo, Ya-Fei Mao, Meng He. High frequency of HGV and TTV infections in blood donors in Hangzhou, WJG, 2001, 7(5): 637-641（SCI）4/5
2. Ya-Fei Mao, Jie Yan, Li-Wei Li, Li shu-ping. Construction of hpaA gene from a clinical isolate of Helicobacter pylori and identification of the fusion protein. WJG, 2003, 9(7):1529-1535（SCI）1/4
3.Jie Yan, Shao-Hui Liang, Ya-Fei Mao, Li-Wei Li, Shu-Ping Li. Construction of expression systems for flaA and flaB genes of Helicobacter pylori and determination of immunoreactivity and antigenicity of the recombinant proteins. WJG, 2003,9(10):2240-2250（SCI）3/5
4.Ya-Fei Mao, Jie Yan. Construction of prokaryotic expression system of ureB gene from a clinical Helicobacter pylori strain and identification of the recombinant protein immunity WJG, 2004, 10(7):977-984
5.Jie Yan, Ya-Fei Mao. Construction of prokaryotic expression system of vacA gene and detection of vacA gene, VacA protein and antibody in Helicobacter pylori isolates and patients’ sera WJG, 2004, 10 (7):985-990
6.Jie Yan, Ya-Fei Mao, Zhe-Xin Shao. Frequencies of the expression of main protein antigens from Helicobacter pylori isolates and production of specific serum antibodies in the infected patients. WJG，2005, 11(3):421-425
7.Ping Ruan, Xiao-Ping Xia, Dexter Sun, David M. Ojcius, Ya-Fei Mao, Wen-Yan Yue, Jie Yan (corresponding author). Recombinant SpaO and H1a as immunogens for protection of mice from lethal infection with Salmonella paratyphi A: Implications for rational design of typhoid fever vaccines. Vaccine, 2008, 26: 6639-6644
8.Luo DJ, Xue F, Ojcius DM, Zhao JF, Mao YF, Li LW, Lin XA, Yan J (corresponding author). Protein typing of major outer membrane lipoproteins from Chinese pathogenic Leptospira spp. and characterization of their immunogenicity. Vaccine, 2009, 28: 243-255.
9.Ai Hua Sun, Ya Fei Mao, Ye Hu, Qi Sun, Jie Yan (corresponding author). Sensitive and specific ELISA coated by TpN15-TpN17-TpN47 fusion protein for detection of antibodies to Treponema pallidum. Clin Chem Lab Med (CCLM), 2009, 47:321-326.
10.Dandan Jin, David M. Ojcius, Dexter Sun, Haiyan Dong, Yihui Luo, Yafei Mao, Jie Yan (corresponding author). Leptospira interrogans Induces Apoptosis in Macrophages via Caspase-8- and Caspase-3-Dependent Pathways. Infect Immun, 2009, 77: 799-809.
11.Haiyan Dong, Ye Hu, Feng Xue, Dexter Sun, David M. Ojcius, Yafei Mao, Jie Yan (corresponding author). Characterization of the ompL1 gene of pathogenic Leptospira species in China and cross-immunogenicity of the OmpL1 protein. BMC Microbiol, 2008, 8: 223-235.
12.Liu Y, Zheng W, Li L, Mao Y, Yan J (corresponding author). Pathogenesis of leptospirosis: interaction of Leptospira interrogans with in vitro cultured mammalian cells. J Med Microbiol Immunol, 2007, 196: 233-239
13.Lei Zhang, Chenglin Zhang, David M. Ojcius, Jinfang Zhao, Xu’ai Lin, Yafei Mao, Liwei Li, Jie Yan (corresponding author). Identification of Mce as a critical outer membrane protein of pathogenic Leptospira species responsible for RGD motif-dependent adherence and host-cell invasion. Mol Microbiol, 2010, In revision.(manuscritp No.: MMI-2010-09754)

五MAJOR CONTRIBUTIONS OF TEXTBOOKS, MONOGRAPHES, NATIONAL STANDARDS AND INVENTION PATENTS
1. Medical Microbiology (textbook). 1st edition, Beijing: the High Education Publication House, 2008. (In Chinese)
2. Leptospirosis (monograph). 3th edition, Peijing: the People’s Healthy Publication House, 2006. (In Chinese)
3． Clinical Molecular Microbiology (monograph). 1st edition, Peijing: the People’s Healthy Publication House, 2005. (In Chinese)
4. Opportunistic Parasitic Disease (monograph). 1st edition, Peijing: the People’s Healthy Publication House, 2009. (In Chinese)

六、AWARDS AND HONORS
Two items of the second grade (2007, 2003) and one item of the third grade (2007) of the Science and Technology Achievement Prize of Zhejing Province, P.R.China.