Profile

Lin-Hua Tan, MD, PhD, Professor of Pediatrics, Chief and Director of Surgical ICU of Children's Hoapital, Zhejiang University School of Medicine.She did an exchange scholarship programme from July 2004 to July 2005 in Texas Children’s Hospital, Baylor College of Medicine, Children's Hospital of Pheladelphia, and Dept. of Integrative Biology and Pharmacology in Texas University in United States. She and her research team has been doing basic as well as clinical research works on pediatric critial care medicine, such as BNP as a sensitive marker to diagnose and predict treatment outcome of patients with heart failure, ECMO as an effective strategy to save citicalli ill patients, PiCCO as a bedside hemodinamically monitoring to guide treatment, ventilator-associated pneumonia, pulmonary hypertension and crisis, Sildenafil regulates potassium channel Kv1.5 mRNA expression and attenuates pulmonary remodling in rats with flow-aasociated pulmonary hypertension, and so on.
二.Publications:
（1）Tan LH, Du LZ, He XJ, Sun MY, Zhang ZW, Lin R. Two successful neonatal extracorporeal membrane oxygenation treatment for severe heart failure after cardiac surgery. Chin Med J (Engl). 2009; 122(21): 2672-2674.
（2）Tan LH, Chang AC. Transhepatic approach as an alternative long-term central venous access in critically ill children with complex congenital heart disease: A new angle to an old problem? Pediatric Critical Care Medicine. 2007; 8（3）: 298-299. （editorial）
（3）Tan LH, Jefferies JL, Liang JF, Denfield SW, Dreyer WJ, Mott AR, Grenier MA, Dickerson HA, Price JF, Towbin JA, Ou CN, Chang AC. Concentrations of brain natriuretic peptide in the plasma predicts outcomes of treatment of children with decompensated heart failure admitted to the Intensive Care Unit. Cardiol Young. 2007;17(4): 397-406.
（4）Tan LH, Hess B, Diaz LK, Cassady CI, Xu ZM, Di Chiara L, Fraser CD, Andropoulos D, Chang AC, Seidel FG. Survey of the use of peripherally inserted central venous catheters in neonates with critical congenital heart disease. Cardiol Young. 2007; 17(2): 196-201.
（5）Zhu LX，Tan LH， He XJ，Zhang CY, Yu YP, Zhang ZW. Postoperative complications and management after arterial switch operation in young infants with transpostion of great arteries. World J Pediatr. 2007; 3(4): 300-304.
（6）Tan LH, Johnson BA, Mawad ME, Chang AC. Neonate with vein of Galen malformation and heart failure: serial changes in plasma B-type natriuretic peptide following endovascular embolization. Pediatric Cardiology. 2006; 27（2）: 276-278.
（7）Tan LH, Jefferies JL, Denfield SW, Dreyer WJ, Mott AR, Grenier MA, Dickerson HA, Price JF, Towbin JA, Ou CN, Chang AC. B-type natriuretic peptide predicts treatment outcomes in pediatric patients with decompensated heart failure in the intensive care setting. Circulation. 2005; 112（17）：U797-U798.
（8）Tan LH，Hess B, Diaz LK, Cassady CI, Xu ZM, Di Chiara L, Fraser CD, Andropoulos D, Chang AC, Seidel FG. Survey of the use of peripherally inserted central venous   catheters in neonates with critical congenital heart disease. Pediatric Critical Care Medicine. 2005; 6: 400.
（9）Tan L, Sun X, Zhu X,Zhang Z, Li J, Shu Q. Epidemiology of  nosocomial pneumonia in infants after cardiac surgery. Chest. 2004; 125(2): 410-417.
（10）Shi S, Zhao Z, Liu X, Shu Q, Tan L, Lin R, Shi Z, Fang X. Perioperative risk factors for prolonged mechanical ventilation following cardiac surgery in neonates and young infants. Chest. 2008; 134(4): 768-774.
（11）Zhang CY, Tan LH, Shi SS, He XJ, Hu L, Zhu LX, Fan J. Noninvasive ventilation via bilevel positive airway pressure support in pediatric patients after cardiac surgery. World J Pediatr. 2006; 2(4): 297-302.
(12）Hu L, Tan LH, Lin R, He XJ, Fan JJ. Sildenafil up-regulate Kv1.5 mRNA expression and attenuates pulmonary remodeling in rats with flow-associated pulmonary hypertension. Journal of Chinese Pediatric Syrgery. 2010（accepted, in press）
（13）Fan JJ, Tan Lh, Zhang ZW, Zhu XK. The impact on outcome of pediatric patients with RSV infection in early period after open-heart surgery. Journal of Chinese Emergency Medicine.2009; 18(11) : 1198-1202.
（14）He XJ, Tan LH, Lin R, Zhang ZW, Du LZ.Successful use of ECMO in a neonate with severe low cardiac output syndrome after open-heart surgery. Journal of Chinese cardiothoracic Surgery. 2009; 25（1）：48-49.
（15）Tan LH, Gong FQ. The perioperative intensive treatment of heart failure in neonates with cyanotic congenital heart disease. Chinese Pediatric Emergency Medicine. 2006; 13(5): 410-413.（review）
（16）Shu Q, Tan LH, Wu LJ, Zhang ZW, Zhu XK, Li JH, Lin R. The risk factors of extubation failure in infants after open-heart surgeyr. Chinese Medicine Journal. 2003; 83(20): 1787-1790.
（17）Tan LH, Li JH, Zhu XK, Zhang ZW, He XJ, Zhang CY. The value of use of prolonged mechanical ventilation in pediatric patients after open-heart surgery. Journal of Chinese Emergency Medicine. 2002; 11(5): 349-350.
（18）Tan LH, Zhu XK, Zhang ZW, Hu J, Li JH, Shu Q. The risk factors of ventilator-associated pneumonia in pediatrics patients after open-heart surgery. Journal of Chinese Cardiothoracic Surgery. 2001; 17(6): 337-338.
（19）Zhu XK, Tan LH, Yu JG, Chen ZL. The significance of postoperative pulmonary arterial pressure in patients with congenital heart disease and severe pulmonary hypertension. Journal of Chinese Anesthesiology. 2002；22(9)：9-11.