Profile

Yulian Wu, M.D，ph.D : 1, Directotr, Professor in the department of Surgery, 2nd Affiliated Hospital, Medical School, Zhejiang University

Honors and Award
1994: Scholarship for Excellect Graduate Student Abroad Ministry of Education, China，
1999-2000: Scholarship for Excellect Postdoctoral Abroad, Ministry of Education, China，
2002-2004：Wyeth-Ayerst Canada Inc. & CIHR/Rx&D Research Program Fellowship
2004: Excellent contribution award for young specialist in medicine by Chinese health Administration

Recent and undergoing research focus on:
1), Searching for novel biomarker from pheripheral serum for detecting early diabete associated pancreatic cancer.
2). Exploring the mechanism of enhancing sensitivity of pancreatic cancer to chemortherapyand.
3) Labeling transplanted mice islet with polyvinylpyrrolidone coated superparamagnetic iron oxide nanoparticles for in vivo detection by magnetic resonance imaging.
4). Monitoring the response rate of pancreatic cancer to chemotherapy by PET and MRI n situ by labeling target molecular particle.
5). The effect of coming molecular target therapy and RFA in HCC and pancreatic cancer.
6）Human bone marrow mesenchymal stem cells differentiate into insulin producing cells upon microenvironmental manipulation in vitro and its potential possibility for autotransplantation in the treatment type II diabetes
7), Protecting primary non function of islet graft for islet transplantation

Recent publication:
Publications
1. Huang H, Dong X, Kang MX, Xu B, Chen Y, Zhang B, Chen J, Xie QP, Wu YL*; Novel
blood biomarkers of pancreatic cancer-associated diabetes mellitus identified by peripheral blood-based gene expression profiles. Am J Gastroenterol. 2010 Jul;105(7):1661-9. IF=6.882
2. Guo Q, Chen Y, Zhang B, Kang M, Xie Q, Wu YL*： Potentiation of the effect of
gemcitabine by emodin in pancreatic cancer is associated with survivin inhibition. Biochem Pharmacol. 2009 Jun 1;77(11):1674-83. IF=4.889
3. Huang H, Xie Q, Kang M, Zhang B, Zhang H, Chen J, Zhai C, Yang D, Jiang B, Wu YL*; Labeling transplanted mice islet with polyvinylpyrrolidone coated superparamagnetic iron oxide nanoparticles for in vivo detection by magnetic resonance imaging. Nanotechnology. 2009 Sep 9;20(36):365101. IF=3.644
4. Xie QP, Huang H, Xu B, Dong X, Gao SL, Zhang B, Wu YL*：Human bone marrow
mesenchymal stem cells differentiate into insulin-producing cells upon microenvironmental manipulation in vitro. Differentiation. 2009 Jun; 77(5):483-91.IF=3.069
5. Dong X, Zhang B, Kang MX, Chen Y, Guo QQ,; Analysis of pancreatic fistula according to the International Study Group Wu YL* on Pancreatic Fistula classification scheme for 294 patients who underwent pancreaticoduodenectomy in a single center. Pancreas. 2011 Mar;40(2):222-8. IF=2.733
6. Guo Q, Zhang B, Dong X, Xie Q, Guo E, Huang H， Wu YL*, . Elevated levels of plasma fibrinogen in patients with pancreatic cancer: possible role of a distant metastasis predictor. Pancreas. 2009 Apr;38(3):e75-9.IF=2.733
7. Guo Q, Kang M, Zhang B, Chen Y, Dong X, Wu YL* ；Eevated levels of CA 19-9 and CEA in pancreatic cancer-associated diabetes. J Cancer Res Clin Oncol. 2010 Nov;136(11): 1627-31. IF=2.485
8. Dong X, Zhan YC, Jiang RY, Xie QP, Peng JP, Wang J, Gao SL, Wu YL*：The Potential Effect of Proteasome Inhibitor PS-341 on Severe Acute Pancreatitis Detected by Positron Emission Tomography in ICR Mice. J Surg Res. 2010 Aug; 162(2):193-202. IF=2.239
9. Huang H, Dong X, Gao SL, Wu YL* ：Conservative resection for benign tumors of the
proximal pancreas. World J Gastroenterol. 2009 Aug 28; 15(32):4044-8. IF=2.24
10. Yan H, Lu D, Xu L, Xie Q, Dong X, Wu YL*. Increased expression level of Olfactomedin4 in peripheral blood mononuclear cells of pancreatic adenocarcinoma patients. Hepatogastroenterology. 2011 Jul-Aug; 58(109):1354-9.
11. Tang Z, Fang H, Kang M, Zhang B, Dong X, Chen X, Xu J, Chen J, Wu YL*. Percutaneous radiofrequency ablation for liver tumors: Is it safer and more effective in low-risk areas than in high-risk areas? Hepatol Res. 2011 Jul;41(7):635-40. IF=1.857
12. Jiang W, Zhang B, Fu YB, Wang JW, Gao SL, Zhang SZ, Wu YL*; Gastric duplication cyst lined by pseudostratified columnar ciliated epithelium: a case report and literature review. J Zhejiang Univ Sci B. 2011 Jan;12(1):28-31 IF=1.027
13. Zhang B, Xie QP, Gao SL, Wu YL*, ：Pancreatic somatostatinoma with obscure inhibitory syndrome and mixed pathological pattern. J Zhejiang Univ Sci B. 2010 Jan;11(1):22-6 IF=1.027
14. Sun CD, Zhang B, Zhang JK, Xu CJ, Wu YL,, Li X, Chen KS；Cyanidin-3-Glucoside-Rich Extract from Chinese Bayberry Fruit Protects Pancreatic β Cells and Ameliorates Hyperglycemia in Streptozotocin-Induced Diabetic Mice. J Med Food. 2011 Dec 19. [Epub ahead of print] IF 1.461