Profile

Professor of Urology, First Affiliated Hospital, Zhejiang University School of Medicine, Zhejiang Province, P. R. China

Education
1978-1982 Bachelor degree, Zhejiang Medical University, Hangzhou, P.R. China
1985-1988 Master degree, Zhejiang Medical University, Hangzhou, P.R. China
1991-1993 M. D., Kiel University, Kiel, Germany
2001.4-7 Visiting professor, West Virginia University
2004.5 Visiting professor, The University of Southern California/Norris Comprehensive Cancer Center
2004.9 Visiting professor, The Brady Urological Institute of Johns Hopkins Hospital
2007.5 Visiting professor, Massachusetts General Hospital, USA
Professional Services
Chairman, Department of Urology, First Affiliated Hospital, Zhejiang University School of Medicine;
Standing Committee Member of Chinese Urological Association;
Vice-Secretary General of Chinese Urological Association;
Standing Committee Member of the Committee of Genitourinary Tumor, Chinese Anti-Cancer Association;
Chairman of the Committee of Genitourinary Tumor, Zhejiang Province Anti-Cancer Association;
Corresponding Member of the European Association of Urology
Publications in recent five years
1. Li Y, Yang K, Mao Q, Zheng X, Kong D, Xie L*. Inhibition of TGF-beta receptor I by siRNA suppresses the motility and invasiveness of T24 bladder cancer cells via modulation of integrins and matrix metalloproteinase. Int Urol Nephrol. 2009 Aug 8. [Epub ahead of print]
2. Mao Q, Zheng X, Jia X, Wang Y, Qin J, Yang K, Bai Y, Xie L*. Relationships between total/free prostate-specific antigen and prostate volume in Chinese men with biopsy-proven benign prostatic hyperplasia. Int Urol Nephrol. 2009 Feb 18. [Epub ahead of print].
3. Yan TZ, Jin FS, Xie LP, Li LC. Relationship between Glucocorticoid Receptor Signal Pathway and Androgen-Independent Prostate Cancer. Urol Int. 2008; 81: 228-233.
4. Mao QQ, Li YB, Zheng XY, Yang K, Shen HF, Qin J, Bai Y, Kong DB, Jia XL, Xie LP*. Up-regulation of E-cadherin by small activating RNA inhibits cell invasion and migration in 5637 human bladder cancer cells. Biochem Biophys Res Commun. 2008, 375(4): 566-570.
5. Jiang J, Zheng X, Qin J, Zheng M, Mao Q, Zhang Z, Cai S, Xie L*. Health-related quality of life after hand-assisted laparoscopic and open radical nephrectomies of renal cell carcinoma. Int Urol Nephrol. 2009; 41(1):23-7.
6. Zheng XY, Xie LP*, Wang YY, Ding W, Yang K, Shen HF, Qin J, Bai Y, Chen ZD.The use of prostate specific antigen (PSA) density in detecting prostate cancer in Chinese men with PSA levels of 4-10 ng/mL.J Cancer Res Clin Oncol. 2008 Nov; 134(11): 1207-10.
7. Yang K, Zheng XY, Qin J, Wang YB, Bai Y, Mao QQ, Wan Q, Wu ZM, Xie LP*. Up-regulation of p21 (WAF1/Cip1) by saRNA induces G1-phase arrest and apoptosis in T24 human bladder cancer cells. Cancer Lett. 2008 Jul 8; 265(2): 206-214.
8. Zheng X, Xie L*, Qin J, Shen H, Chen Z, Jin Y. Effects of wortmannin on phosphorylation of PDK1, GSK3-beta, PTEN and expression of Skp2 mRNA after ischemia/reperfusion injury in the mouse kidney. Int Urol Nephrol. 2008; 40(1): 185-92.
9. Xie LP*, Bai Y, Zhang XZ, Zheng XY, Yao KS, Xu L, Zeegers M. Obesity and Benign Prostatic Enlargement: A Large Observational Study in China. Urology, 2007, 69(4): 680-684.
10. Qin J, Xie LP*, Zheng X, Wang Y, Bai Y, Shen H, Li LC, Dahiya R.A component of Green Tea, (-)-epigallocatechin-3-gallate, promotes apoptosis in T24 human bladder cancer cells via modulation of the PI3K/Akt pathway and Bcl-2 family proteins. Biochemical and Biophysical Research Communications, 2007, 354(4): 852-857.
11. Xie LP, Zheng XY, Qin J, Chen ZD, Jin YF, Ding W. Role of PI3-kinase/Akt signaling pathway in renal function and cell proliferation after renal ischemia/reperfusion injury in mice. Nephrology, 2006, 11(3): 207-212.
12. Xie LP*, Qin J, Zheng XY, Chen ZD. Undescended epididymo-testicular metastasis from prostatic carcinoma. Asian Journal of Andrology, 2006, 8 (2): 251-252.
13. Jian L, Xie LP, Lee AH, et al. Protective effect of green tea against prostate cancer: a case-control study in southeast China. Int J Cancer. 2004, 108(1): 130-135.

Patents
1． A new nephroprotective amino acid mixture.
2． Bladder manipulator used in laparoscopy.
3． Multichannel laporoscopic trocar.
4． Support devices for laparoscopic surgeries.
5． Separator for extraperitoneal space in laparoscopic surgeries.
6． Mushroom-like temporary stent for prostate.
7． Trocar for percutaneous resection of bladder tumor.
8． Balloon temporary stent for prostate.
9． Deflectable device for laparoscopic surgeries.
10． Balloon-tipped intravesical slow-release capsule.