FACULTY

Researchers Reveal the Secrete of Nonrandom DNA Seg-regation in Human Cells

2019-09-03   |  
Name: YaoHua
Post: Associate Professor
Position:
Education: Ph.D.
Professional: oral medicine
Departments: The First Affiliated Hospital
Research: study on mechanisms of oral precancerous diseases
TEL: 87236338
E-mail: yaohuauk@hotmail.com
Personal Home Page:

Profile

Education and Training:
2009.12-2010.1 Graduate Center for Toxicology, College of Medicine, University of Kentucky, Lexington, Kentucky, U.S.A, Short-term Scholar
2008.12--2009.1 Graduate Center for Toxicology, College of Medicine, University of Kentucky, Lexington, Kentucky, U.S.A, Short-term Scholar
2007.1--2008.2 Graduate Center for Toxicology, College of Medicine, University of Kentucky, Lexington, Kentucky, U.S.A, Postdoctoral training
2001.2--2005.6 Dept. of Stomatology, College of Medicine, Zhejiang University, Hangzhou, Zhejiang, PR. China, Ph.D. in Stomatology.
1995.9--1998.8 Zhejiang Medical University, Hangzhou, Zhejiang, PR. China, Master in Stomatology.
1990.9-- 1995.6 Zhejiang Medical University, Hangzhou, Zhejiang, PR.China, Bachelor in Stomatology

Work experience:
1998 - present Doctor/Dentist, Department of Stomatology, the First Affiliated Hospital, College of Medicine, Zhejiang University, China.
I work on the diagnosis and treatment of oral cancer, oral membrane diseases, and oral precancerous diseases.
I also work as a dentist, majoring on conservative dentistry.

Grants and Honors:
2009.1-2011.12 Sulforaphane inhibits nickel induced carcinogenesis on tongue cancer cells. Granted by the Bureau of Health in Zhejiang, PR China.
2009.1-2011.12 Sulforaphane inhibits apoptosis on tongue cancer cells. Granted by the Bureau of Health in Zhejiang, PR China.
2008.1-2010.12 Sulforaphane inhibits proliferation on tongue cancer cells. Granted by the Ministry of Education of People’s Republic of China.
2005.1---2007.12 KUSENJIAN inhibit telomerase activation on tongue cancer cells. Granted by Administration of Traditional Chinese Medicine in Zhejiang, PR China.
2005---2006 The effect of TNF-related apoptosis-inducing ligand adenovirus on tongue cancer cells.Granted by Zhejiang Provincial Natural Seience Foundation of China.
2004---2006 The preventing effect of Matrine on tumorigenesis of oral cancer. Granted by Administration of Traditional Chinese Medicine in Zhejiang, PR China.
2003---2005 Inhibitory effect of antisense oligodeoxynucleotides against hTERT on telomerase and proliferation of human tongue squamous cell carcinoma. Granted by the Bureau of Health in Zhejiang, PR China.

2006.05 The expression of MAGE-A1 and A3 genes in human tongue cancer and salivary carcinomas. The Third Prize for Progression on Science and Technology by Education Bureau of Zhejiang Province,PR China
2001.12 Detection and clinical effect of telomerase activity in oral squamous cell carcinoma and precancerous lesions. The First Prize for Progression on Health Science and Technology by the Bureau of Health in Zhejiang, PR China.
2001.12 Detection and clinical effect of telomerase activity in oral squamous cell carcinoma and precancerous lesions. The Second Prize for Progression on Science and Technology by Zhejiang Province, P. R. China

Publications:
1.Induction of apoptosis in human leukemia cells by grape seed extract occurs via activation of c-Jun Nh2-terminal kinase. Clinical Cancer Research 2009;15:140-149
2.Oxidative stress and chromium carcinogenesis. Journal of Experimental Pathology, Toxicology, and Oncology 2008;27:77-88,
3.Sulforaphane inhibited expression of hypoxia-inducible factor-1α in human tongue squamous cancer cells and prostate cancer cells. International Journal of Cancer 2008;123:1255–1261,
4. Effect of tea polyphenols on hTERT gene expression of human Tca8113 cell lines: A preliminary study. International Journal of Oral and Maxillofacial Surgery. 2006;35(4):352-355
5.The effect of gemcitabine on proliferation and telomerase activity of oral Tca8113 cell lines. Shanghai Kou Qiang Yi Xue 2005;14(1):59-62.
6. Inhibiting effects of tea polyphenols on cell proliferation and hTERT of human Tca8113 cell lines. Zhonghua Kou Qiang Yi Xue Za Zhi .2005,40(6):451-454
7. The Effects of Arsenic Trioxide (As2O3) on the Cell Apoptosis and hTERT mRNA of human tongue cancer cells. Huaxi Kou Qiang Yi Xue Za Zhi,2005,23(5):442-445
8. A clinical evaluation of filling for cervical wedge-shaped defects of teeth using two different bond and composite.Journal of Modern Stomatology. 2004;18(4):337-338
9. A research of intracanal medicant to prevent from pain after endodontic preparation. Journal of Practice Stomatology. 2004;20(4):505-506
10. Preventive effect of intracanal medication against pain after root canal preparation in patients with pulptitis. Zhejiang Prevent medicine. 2004;16(9):7-9
11.Proteome and Oral tumor.Guo Wai Yi Xue (Kouqiang Fen Ce).2003, 30(6):417-419
12. Detection and effect of telomerase activity in oral mucosal squamous cell carcinoma. Zhonghua Kou Qiang Yi Xue Za Zhi 2000 ;35(4):269-70.
13.Study and detection of telomerase activity in oral squamous cell carcinomas and precancerous lesions. Zhonghua Kou Qiang Yi Xue Za Zhi. 1999; 34(6):328-30
14. Expression and effect of EGFR in oral squamous carcinoma and precancerous lesions.Kou Qiang Yi Xue.1999;19(1):1-3
15.The content of estradiol receptors in oral mucosa precancerous lesions and its effect. Shanghai Kou Qiang Yi Xue 1998;7(4):204-206