Profile

CURRICULUM VITAE

Name: Yu Hai（余 海）, M.D., Ph.D. Sex: Male
Date of birth: March 11, 1945 Place of Birth: Shanghai, China
Nationality: Chinese
Marital status: Married with one daughter and one son

Address: Zhejiang University School of Medicine
388 Yuhangtang Road
Hangzhou 310058
China P.R
Telephone: +86-571 88208060
Fax: +86-571 88208097
Email: yuhai@zju.edu.cn


EDUCATION

1980 1983 Cancer Research Unit, University of Leeds, Leeds, U.K., Ph.D.
1962 1968 Department of Medicine, Shanghai First Medical University, M.D.

PROFESSIONAL EXPERIENCES

2009- Senior Consultant, China Medical Board
2005- Director, International Education Programs, ZUSM
1999-2002 Associate Dean, Zhejiang University School of Medicine
1996-1998 Vice-President, Zhejiang Medical University
1995 Visiting Professor, Oncology Immunology Research Centre, Pharmacia, Lund, Sweden
1992- Professor, Zhejiang Medical University (Zhejiang University School of Medicine)
1989 1996 Deputy Director, Cancer Institute, Zhejiang Medical University
1986 1992 World Bank Project Consultant, Chinese Ministry of Health.
1984 1996 Cancer Institute, Zhejiang Medical University, (1986 Associate professor)
1978 1979 Assistant Lecturer, Department of Pathology, Ningxia Medical College
1968 1978 Physician, in Longde County, Ningxia Hui Autonomous Region

ACADEMIC SOCIETIES

Vice-Chairman, Chinese Association of Clinical Epidemiology
Vice-Chairman, Chinese Association of Family/General Medicine
Standing Member, Zhejiang Provincial Medical Association
Chairman, Board of General/Family Medicine, Zhejiang Provincial Medical Association
Vice-Chief Editor, Chinese Journal of Family Physician
Vice-Chief Editor, Journal of Zhejiang University (Medical Sciences)
Member, Editorial Board of following journals:, Education and Clinical Practice of Family Medicine, Journal of Oncology, Journal of Practical Oncology, Journal of Applied Oncology, Zhejiang Journal of Medicine, Medical Practice Journal, Journal of Modern Applied Medicine.


Research Grants

1. The basic study on electroporesis and electrofusion of cells in biomedical research. Nature Science Foundation of China (NSFC) grant 1989-1992
2. The study on electrofusion of mammalian cells. Nature Science Foundation of Zhejiang (NSFZ) grant 1989-1992
3. The measurement and clinical application of urinary secondary amines. Grant of Zhejiang Educational Bureau 1988-1991
4. The development of occult blood test with immuno-spot method. Grant of Zhejiang Health Bureau 1991-1993
5. Antibody-targeted superantigen in treatment of colorectal cancer. NSFZ grant 1996-1999
6. Monoclonal antibody - superantigen fusion protein in enhancing the effect of cancer vaccine. NSFC grant 1998-2000
7. The construction of expression vector of transmembrane superantigen and its antirumor effects. NSFZ grant 2000-2003
8. The preparation of antitumor vaccine with mutated transmembrane superantigen.
NSFZ Grant 2002-2004

Grant from China Medical Board

1. Comprehensive screening for common cancers. CMB Grant #92-559 1992-1997
2. Problem Solving for Better Health. CMB Grants #95-623 and Dreyfus Health Foundation 1995-2000
3. Undergraduate and postgraduate education of family medicine. CMB Grant #98-696 1999-2004
4. Computer assisted instruction in medical education CMB Grant #99-703 2000-2005
5. Distance medical education CMB Grant # 99-704 2000-2005
6. Integrated Medical Education CMB Grant #05-823 2006-2013
7. Health Policy Development in China’s Medical Universities CMB Grant #08-904 2008-2012



PUBLICATION

Ph D thesis
The Biochemical Evaluation and Clinical Significance of Tubular and Post renal Proteinuria. Submitted to Leeds University, U.K. for PhD degree , April 1983.

Books
1. Advances in Clinical Oncology. Zhejiang Med Univ Press 1988
2. The Care and Rehabilitation of Cancer Patients. Zhejiang Science & Technology Publication House 1997 Hangzhou
3. Introduction to Family Medicine. Sichuan Science & Technology Publication House, 2001 Chengdu

Book Chapters
1. Biochemical and Immunological Aspect of Bladder Cancer in man. In: Elsebai eds. Bladder Cancer CRC Press, Boca Raton Florida,1983 pp54 79,
2. Tubular Proteinuria after Burn Injury. In: Lubec & Compese eds. Advances in Non invasive Nephlogy, John Libbey, London 1985
3. Fast Protein Liquid Chromatography in the Separation of Urinary Proteins. In: Lubec & Compese Eds Advances in Non invasive Nephlogy, John Libbey, London, 1985
4. Nutritional Therapy of Cancer Patients. in: CJ Zhao eds. Manual of Clinical Nutrition, Zhejiang Science Press 1993
5. Prevention of Colorectal Cancer, In: TZ Zhang & GW Xu eds. Oncology Tianjin Science and Technology Press 1996
6. Application of Clinical Epidemiology in Oncology Research. In: Wang Jialiang eds. Clinical Epidemiology. Shanghai Science and Technology Press. 2001, Shanghai
7. Prevention of Colorectal Cancer in Zheng Shu Ed Colorectal Cancer: Scientific Foundation and Clinical Practice People’s Publishing House March 2006 Beijing


Papers

1. Yu H, Glashan R, Robinson MRG, Richards B, Fryzman A, Daponte D and Cooper EH. Changes in the Urine Protein Profile following Intravesical Doxorubicin. J Urol, 1982, 128:271 27
2. Yu H, Cooper EH, Settle JAD and Meadows T. Urinary Protein Profile after Burn Injury. Burns 1983, 9:339 349.
3. Yu H, Yanagisawa Y, Forbes MA,Cooper EH,Crockson RA and MacLemman ICM. Alpha 1 microglobulin, an Indicator Protein for Renal Tubular Function. J Clin Path 1983, 36:253 259
4. Cooper EH, Yu H and Morgan DB. Tubulare Proteinurie. Laboratoriumslatter 1982 32:1 15
5. Marshall RJ, Yu H, Turner R and Cooper EH. Computer Analysis of Chromato- graphic Profile of Urine Proteins. In: Proceedings of Third International Symposium on HPLC of Proteins, Peptides and Polynucleotides. Nov 14 16 1983, Monte Carlo, Monaco
6. Cooper EH, Turner R, Yu H and Linblom. Fast Protein Liquid Chromatography in the Separation of Urinary Proteins.In: Proceedings of International Conference on non invasive Diagnosis of Renal Diseases. Sept. 11 14 1983 Vienna
7. Yu H, Marshall R, Cooper EH and Settle JAD.Tubular, Proteinuria after Burn Injury. idem.
8. Cooper EH, Yu H and Morgan DB. La Proteinuria Tubulare. Ric Clin Lab 1983 13 (suppl2): 31 43.
9. Bird HA, Yu H and Cooper EH. Renal Proximal Dysfunction in Patients with Rheumatic Diseases.Br Med J 1984 7:288(6423):1044 1045
10. Marshall RT, Turner R, Yu H and Cooper EH. Cluster Analysis of Chromatographic Profiles of Urine Proteins. J Chromatogr 1984 297:235 2
11. Cooper EH, Yu H and Glashan RW. Proteinuria after Intravesical Chemotherapy. In: Proceedings of Conference on Chemotherapy of Bladder Cancer. May 1985 York
12. Sandberg T, Cooper EH, Lidin Janson G and Yu H. Fever and Proximal Tubular Function in Acute Pyelonephritis. Nephron 1985; 41:39 44
13. Yu H, Zheng HL et al. The Measurement of Urinary Secondary Amine and its application in Cancer Diagnosis. Acta Zhejiang Agricultural Univ 1987, 13(2):207
14. Zheng S, Yu H et al. Estrogen Receptor Status of Breast Cancer and Prediction of Chemotherapy Sensitivity. Presented at 15th International Congress of Chemotherapy, July 19 24 1987 Istanbul Turkey
15. Zheng S, Yu H et al. Estrogen Receptors in Breast Cancer and Its significance in Prediction of Chemosensitivity. Acta Acad Med Sinicae 1988 10(3):157
16. Yu H & Yu D. The Research on Monoclonal Antibody in China. J Practical Oncology 1988, 3:79
17. Yu D and Yu H: A Review and Comments on Subrenal Capsule Assay of Anticancerous Chemo-therapeutic Sensitivity. Zhejiang Cancer Bulletin, 1989;1:56
18. Shen XQ and Yu H: Polyamine and Cancer (review) Zhejiang Cancer Bulletin 1989;4:45
19. Guo YS, Yu H et al. The Principle of XR 1 Electric Cell Fusion apparatus. Acta Zhejiang Med Univ.1989;18(4):15
20. Yu H, Hua YB et al. The Preliminary Application of Self made Electric Cell fusion Apparatus. Acta Zhejiang Med Univ 1989;18(4):153
21. Yu H et al. RPHA FOB Tests in Screening of Colorectal Cancer in a High Risk Population. Chinese J Oncol 1990,12(2):108
22. Liu KB, Yu H et al. Protoplasm electrofusion of Lycopersicon esculentum and L.hirsutum. Wuhan J of Botanic Res 1990,8(3):273
23. Wang M, Yu H et al. The Experimental Study of Human Colorectal Cancer by Polyamine Biosynthesis Inhibitor DFMO. Acta Acad Med Sinicae 1990, 12(4): 269
24. Wu JM, Yu D and Yu H: Study of Methodology of Subrenal Capsule Assay. J Prac Oncol 1990, 5(1):40
25. Yu Hai: The Strategies of Large Bowel Cancer Control. China Cancer Information 1990, 5:23
26. Chen FH, Yu H et al. Toxic Effect of liposome encapsulated MTX on bone Marrow Cell in Mice. J Zhejiang Med Univ 1990,19(5):198
27. Chen FH, Yu H et al. Tissue Distribution of Liposome encapsulated Methotrexate in S 180 Tumour Bearing Mice. idem 19(6):263
28. Yang Hua and Yu Hai: Biological Response Modifiers: Cimetidine, BCG, Lantenen and their Clinical Applications. J Prac Oncol 1990; 5(4):201
29. Shen XQ, Yu H: Polyamine and Cancer. Guoweiyixue Oncology 1990; 2:82
30. Shen XQ and Yu H: Progesterone Receptor in Breast Cancer. Zhejiang Medicine 1990;12(5):31
31. Wang M and Yu H: Anticancerous Effect of Polyamine Biosynthesis Inhibitors. J Prac Oncol 1991;6(1):56
32. Chen FH, Yu H et al. The Inhibitory Effect of Liposome encapsulated Methotrexate on Large Bowel Cancer Cell Line.Research on Cancer Prevention & Treatment 1991;18(1):11
33. Wang M, Yu H et al. Inhibition by Polyamine Biosynthesis Inhibitor DFMO on the Growth of Transplanted Human Colon Cancer in Nude Mice. Chinese J Oncol 1991; 15(5):335
34. Sun YL, Wang MH and Yu H: The Application of TNF in Cancer Diagnosis and Treatment. J Pract Oncol 1991; 6(2):126
35. Zheng S, Yu H et al. The Diagnostic Criteria of Infrared Thermography in Breast Cancer. Tumor (Shanghai) 1991; 11(3):103
36. Zheng S, Yu H et al. The Screening Model for Early Diagnosis of Colorectal Cancer in General Population. Natl Med J China. 1991;71(7):381
37. Yu Hai: The Molecular Biological Basis of Colorectal Cancer. Zhejiang Cancer Bulletin. 1991;2:56
38. Zheng S, Yu H et al. The Establishment and Evaluation of Population Screening Model for Colorectal Cancer. Medical Research Letter 1991; 20(9):6
39. Chen FH, Yu H et al. Inhibitory Effect of MTX Liposome on Large Bowel Carcinoma of Mice. Tumor (Shanghai) 1991;11(6):32
40. Chen LR and Yu H: The Research Progress of Oncogene and anti-oncogene. J Pract Oncol 1991;6(3):181
41. Wang M, Yu H et al. Inhibitory Effect of DFMO on in vitro Growth of Large Bowel Carcinoma Cell Line. Tumor (Shanghai) 1991;11(6):32
42. Wang Min, Yu Hai, Zheng Shu et al. Inhibitory Effect of DFMO on the Growth of Transplanted Human Colon Cancer in Nude Mice. Chin J Cancer Res 1991;3(4):18
43. Shen DJ, Yu H et al. Experimental Study of Dot ELISA in Detection of Fecal Occult Blood. J Zhejiang Med University 1992; 21(1):4
44. Yang G, Yu H et al. Environmental and Inheritary Factors in Large Bowel Cancer. Chinese J Epidemiol 1992;13(1):30
45. Zheng S, Yang G, Yu H et al. A Preliminary Report on Early Detection and ///" Cancer Insurance///". J Pract Oncol 1991;7(1):27
46. Gan YB, Zheng S, Yu H and Muller P. Study of experimental conditions of RNA-RNA in situ hybridization. Biotechnology 1991; 1(6):15
47. Che J, Yu D and Yu H: Preparation of the Conjugate between Anti colorectal cancer Monoclonal Antibody and Bleomycine and its anticancerous Activity. Clin Oncol China 1992;19(2):142
48. Yang G, Yu H et al. A Comparison of Mortality Rate of Colorectal Cancer in Youth of Different Races. J Zhejiang Med Univ 1992;21(2):84
49. Shen XQ, Yu H et al. Comparative Study of Single point and Multi point Method of Estrogen and Progesterone Receptors Measurement in Breast Cancer. Chinese J Oncol 1992;14(2):142
50. Yu H et al. Evaluation of RPHA Fecal Occult Blood Test in Screening of Colorectal Neoplasia. Tumor (Shanghai) 1992;12(4):160
51. Chen LR, Zheng S, Yu H et al. Clinic pathological Analysis of Colorectal Cancer Detected in Population Screening (21 cases) J Pract Oncol 1992;7(2):7
52. Yu D,Yu H et al. The application of MTT colorimetric assay in cancer biological research. J Prac Oncol 1992;7(3):167
53. Chen LR, Yu H et al. The expression of lectin receptors in rectal cancer and metastatic lymph node J Prac Oncol 1992;7(3):146
54. Gan YB, Yu H et al. Expression of Type I and Type III procollagen genes in human scirrhous carcinoma of breast by in situ hybridization. Chinese J Oncol 1992; 14(5):348
55. Wu Wei and Yu Hai. Taxol - A noval chemo-therapeutical agent. Guoweiyixue Oncoloty 1992; 19(suppl):66
56. Wang SW, Li RF and Yu H: The application of MRI in diagnosis of breast cancer. J Pract Oncol 1993, 8(4):253
57. Hu X and Yu H. The Electron-microscopic observation of cell fusion. J Zhejiang Med Univ 3;22(3):112
58. Yu D, Yu H et al. The establishment of transplanted human colon cancer model in nude mouse and its characteristics. J Zhejiang Medical Univ 1993; 22(3):112
59. Yang H and Yu H. The biological effect and clinical application of colony-stimulating factors. J Pract Oncol 1993;8(2):75
60. Shen DJ, Zheng S and Yu H. The preliminary observation of autocrine phenomenon in rectal cancer cell line HR-8348. J Zhejiang Med Univ 1993;22(2):65
61. Hu X and Yu H. The effect of electric broken on the survival of K562,NS-1 and mouse spleen cells. J Cell Biology 1993;15(3):136
62. Yu Hai. New Methods for early detection of large bowel carcinoma. J Med Theory and Pract 1993;6(5):17
63. Wang XJ and Yu H.The mechanism of tamoxifen in treatment of breast carcinoma. Guowei Yixue Oncology 1993, 20(Suppl):96
64. Zheng S, Yu H et al. Optimization of Screening protocol for Colorectal Cancer in General Population. Zhejiang Cancer Bulletin 1993; (1):18
65. Zhou L, Yu H et al. A case-control study of risk factors of colorectal cancer based on the population screening. Chinese J Chron Dis Prev & Control 1993; 1(5):213
66. Chen K, Yu H et al. An applied study on the method of multi-factorial quantitative-risk assessment for mass screening of colorectal cancer. Chinese J Oncol 1993;15(1):37
67. Zhou L, Yu H et al. Analysis of risk factors related to colorectal polyps. Chinese J Zoonoses 1993; 9(Suppl): 18
68. Chen K, Yu H et al. Evaluation of small area survey and sampling in epidemiological studies. Chinese J Zoonoses 1993;9:35
69. Yu Hai, Hu Xun, Shen Xiqiang et al. Evaluation of Serum Acid-Soluble Protein in Clinical Diagnosis. Chin J Clin Oncol 1994;21(3):8
70. Gan Yuebo, Zheng Shu, Yu Hai et al. Localization of Type I and Type III Procollagen mRNAs in Breast Scirrhous Carcinoma by in situ Hybridization. Chin J Cancer Res 1994 6(2):108
71. Zhou Lun, Yu Hai, Chen Kun et al. Risk Factors of Colorectal Adenoma in High-incidence Area. Chin J Clin Oncol 1994; 21(12):884
72. Yu Hai The Methodology of Evaluation in Clinical Application of Tumor Markers. J Prac Oncol 1994;9(4):204
73. Yu Hai, Zhou Lun et al. Evaluation of RPHA Fecal Occult Blood Test in Screening of Colorectal Neoplasia. Chin J Cancer Res 1994; 6(4):274
74. Lu Mei, Yang Mingda and Yu Hai. The precancerous lesion of oral cavity and the surveillance of its carcinogenesis. Guo Wei Yi Xue Stomatology 1994, 2(6):345
75. Lu M, Yang MD and Yu H: Superoxide dismutase in DMBA-induced carcinogenesis of Syrian hamster bucca pouch. Chinese J Oral & Maxillofacial Surgery 1995, 5(1):27
76. Chen K, Jiao DA, Yu H et al. The value of occult blood test as an indicator of colorectal cancer.
Tumor 1995,15(2):155
77. Zheng S, Zhou L, Yu H et al. A case-control study of colorectal cancer in six regions of China.or 1995, 15(2):149
78. Chen WY, Zheng S and Yu H. A research of induced multidrug resistance of EHR cells in vivo. Zhejiang Cancer J 1995;1(4):225
79. Wu W, Yang H, Yu H et al. Effect of sodium butyrate on cytodynamics and ultrastructure in cell line SW1116. J Prac Oncol 1995;10(4):232
80. Yu D, Yu H, et al. The immune reconstruction in T-cell immunodeficient NC nude mice and its inhibitory effect on human colon cancer. Acta Oncologica Sinica 1995;5(4):261
81. Lu M, Yang MD and Yu H. Flow cytometry analysis fo carcinoma cells of Syrian hamster bucca pouch induced by DMBA. Chin J Stomatology 1996;31(1):61
82. Yu Hai, Sun Qirong et al. Detection of mucin T-antigen with GOS test kits in large bowel neoplasms. J Prac Oncol 1996 11(3): 115
83. Zheng S, Yu H et al. The comprehensive screening for common malignant tumors of digestive tract. J Prac Oncol 1996; 11(4):188
84. Huang J, Wu JM ,Yu H et al. Clinicopathological parameters and multivarient Cox regression model in prognosis of colorectal cancer. China Clin Oncol 1996;11(5):208
85. Huang JQ Yu H et al. The value of infrared thermography in differential diagnosis between malignant and benign breast lamps. J Pratic Oncol 1996; 11(5):75
86. Zhou L Yu H et al. The risk factors of colorectal cancer in Hangzhou region Acta Zhejiang Med Univ 1996;25(5):204
87. Zhou L Yu H et al. Verification of the optimized screening protocol of colorectal cancer in high-incidence area. Chinese J Chronic Disease Prevention & Control 1997;5(2):75
88. Zhou Lun Yu Hai and Zheng Shu, Evaluation of fecal occult blood test with reverse passive hemaggutination test for colorectal neoplasm screening. China Natl J New Gastroenterol 1997;3(1):38
89. Wang Qingqing and Yu Hai Monoclonal antibody-conjugated superantigen in cancer therapy. Guowai Yixue Oncology 1996;23(5):26
90. Wang Qingqing and Yu Hai Superantigen and T cell activation J Zhejiang Med Univ 1997;26(3):140
91. Gong Yang, Wei Zheng, Hai Yu et al. Pathologic features of Initial Adenomas as predictors for Metachronous Adenomas of the Rectum. Journal of the National Cancer Institute, 1998, 90(21):1661
92. Zhou Lun, Yu Hai, Zheng Shu, et al. The value of “occult blood bead” in detection of upper digestive tract disorders with bleeding. Chin I Oncology, 1999;21(1):48-50
93. Wang Qing-qing Yu Hai and Yu Da Preliminary study on antitumor effect of C125 gene transfected tumor vaccine and monoclonal antibody-superantigen fusion protein C215Fab-SEA Chinese Journal of Immunology 2000; 16(12):40-43
94. Wang Qingqing Yu Hai et al. Intratumoral IL-18 Gene Transfer Improves Therapeutic Efficacy Of Antibody-Targeted Superantigen In Established Murine Melanoma. Gene Therapy. 2001; 8: 542- 550
95. Pan Jianping, Yu Hai et al. Dexamethasone inhibits the antigen presentation of dendritic cells in MHC class II pathway. Immunology Letter. 2001 April; 76: 153-161
95. Q Wang, H Yu et al. Vaccine with IL-18 gene modified, superantigen-coated tumor cells elicits potent antitumor immune response. J Cancer Res Clin Oncol. 2001; 127(12):718-726
96. Yu Hai From empiristic medicine to clinical science. J Zhejiang Med 2001; 23(12):707
97. Yu Hai Clinical medicine and clinical epidemiology of the 21th Century. Chinese Int J Med 2002;2(1):5
98. Q Wang, H Yu et al. Adenovirus-mediated intratumoral lymphotactin gene transfer potentiates the antibody-targeted superantigen therapy of cancer. J Mol Med 2002 Sep；80(9):585-94
99. Zhou Lun, Yu Hai and Chen Kun. Relationship between microcystin in drinking water and colorectal cancer. Biomedical and Environmental Sciences 2002 15:166-171
100. Xiaohong Chen, Qun Tao, Hai Yu et al. Tumor cell membrane-bound heat shock protein 70 elicits antitumor immunity. Immunology Letters 84(2002)81-87
101. Zheng S, Chen K, Liu X, Ma X, Yu H et al. Cluster randomization trial of sequence mass screening for colorectal cancer. Dis Colon Rectum 2003 Jan; 46(1):51-8
102. Yu Hai. The origin, development and implication of general/family medicine. J Edu Cli Pra Fam Med 2003; 1(1): 3
103. Du Yaping, Yu Hai et al. The current status of family medicine education in Zhejiang Province. Journal of General Practice 2003; 8(1) 55-58
104. Ma Wenxue, Yu Hai et al. Expression of the fusion protein of transmembrane- superantigen SEA and its antitumor effects. Chin J Microbiol Immunol 2003; 23(7):567-571
105. Ma wenxue, Yu Hai, et al. Antitumor effects of the fusion protein of transmembrane staphylococcal enterotoxin A Chin J Pharmacol Toxicol 2003; 17(6):426-431
106. Wenxue Ma, Hai Yu, Qingqing Wang, et al. In vitro biological activities of transmembrane superantigen staphylococcal enterotoxin A fusion protein Cancer Immunology, Immunotherapy 2004; 53(2):118-124
107. Changxin Huang, Hai Yu, Qingqing Wang et al Potant antitumor effect elicited by superantigen-linked tumor cells transduced with heat shock protein 70 gene. Cancer Science February 2004; 95(2):160-167
108. Wenxue Ma, Hai Yu, Qingqing Wang, Hongchuan Jin, Joyce Solheim and Vinod Labhasetwar. A novel Approach for Cancer Immunotherapy: Tumor Cells with Anchored Superantigen SEA Generate Effective Antitumor Immunity. J Clinical Immunology 2004; 24(3):293-301
109. Pingyong Yi, Hai Yu, Wenxue Ma and Qingqing Wang. Preparation of Murine B7.1-Glycosylphosphatidylinositol and Transmembrane-Anchored Staphylococcal Enterotoxin: A Dual-Anchored Tumor Cell Vaccine and its Antitumor Effect. Cancer 2005; 103(7):1519-1528
110．Changxin Huang, Hai Yu, Qingqing Wang, et al. A novel anticancer approach: SEA-anchored tumor cells expressing heat shock protein 70 onto the surface elicit strong anticancer efficacy. Immunology Letters 101(2005) 71-80
111. Hongliang Huang, Guping Tang, Qingqing Wang, Da Li, Fenping Shen, Jun Zhou and Hai Yu* Two novel non-viral gene delivery vectors: low molecular weight polyethylenimine cross-linked by (2-hydroxypropyl)-b-cyclodextrin or (2-hydroxypropyl)-c- cyclodextrin Chem. Commun. 2006, 2382–2384
112. Li Da, Wang Qingqing, Tang Guping, Li Jingzhong, Huang Hongliang, Shen Fenping, Yu Hai The Physicochemical characteristics of polyethylenimine modified by CP9 containing RGD peptide. Journal of Zhejiang University (Medical Sciences) 2006;35(6):615-621
113. Li Da, Wang Qingqing, Tang Guping, Huang Hongliang, Shen Fenping, Li Jingzhong, Yu Hai. Receptor-mediated gene delivery using polyethylenimine (PEI) coupled with polypeptides targeting FGF receptors on cell surface. Journal of Zhejiang University (Science B) 2006 7(11)：906-911
114. Li Da, Wang Qingqing, Tang Guping, Huang Hongliang, Li Jinzhong, Shen Fenping, Yu Hai, The application of low molecular weight polyethylenime in cancer gene therapy. J Practical Oncology 2006， 21（6）：527－530
115． Li Da, Wang Qingqing, Yu Hai Research progress of peptides as the component of non-viral transgenic vector. International Journal of Biomedical Engineering 2006，29（5）：307-310
116. D. LI, G. P. TANG, J. Z. LI , Y. KONG, H. L. HUANG, L. J. MIN,J. ZHOU, F. P. SHEN, Q. Q. WANG, and H. YU: Dual-targeting non-viral vector based on polyethylenimine improves gene transfer efficiency. J. Biomater. Sci. Polymer Edn, Vol. 18, No. 5, pp. 545–560 (2007)
117. DA LI, HAI YU, HONGLIANG HUANG, FENPING SHEN,XIAOYUAN WU, JINGZHONG LI, JIANLI WANG, XUETAO CAO, QINGQING WANG,AND GUPING TANG: FGF Receptor-mediated Gene Delivery using Ligands Coupled to Polyethylenimine. J Biomater Appl 2007; 22（2）：163-179
118. Hongliang Huang, Hai Yu, Da Li, Yang Liu, Fenping Shen, Jun Zhou, Qingqing Wang and Guping Tang, A Novel Co-polymer Based on Hydroxypropyl α-Cyclodextrin Conjugated to Low Molecular Weight Polyethylenimine as an in Vitro Gene Delivery Vector Int. J. Mol. Sci. 2008, 9, 2278-2289