Profile

NAME: Wei Zhang
WORK PHONE NUMBER: 0571 88208130
CELL PHONE NUMBER: 13819103401
EMAIL: zwei72@163.com, zwei72@zju.edu.cn
CURRENT JOB TITLE: associate professor

EDUCATIONS:
Bachelor Degree: Zhejiang Medical College, 1994
Master Degree: Pathology and Pathophysiology, Zhejiang University, School of Medicine, 2000.
Doctor of Philosophy: Oncology, Zhejiang University, School of Medicine, 2007.

PROFESSIONAL EXPERIENCES:
1994.9----1999.11 Assistant teacher of pathology in Zhejiang Medical College.
1999.11----2008.12 Lecturer of pathology in Institute of Pathology & Forensic Medicine, Zhejiang University
2008.12----present Associate professor of pathology in Institute of Pathology & Forensic Medicine, Zhejiang University

RECENT RESEARCH FIELD:
(1) The suppressing effect and mechanism of APOBEC3 cytidine deaminases on HBV .
(2) The role of human APOBEC3 cytidine deamineases in oncogenesis.
(3) Characters of gene expression profile and corresponding molecular markers in malignant lymphoma.

RESEARCH PROJECT IN CHARGE:
(1). The role of APOBEC3B and hnRNP K in the pathogenesis of hepatocellular carcinoma. National natural science fundation, No.30973381, 2010-1-1 to 2012-12-31
(2). The role of APOBEC3B and hnRNP K in the pathogenesis of hepatocellular carcinoma. Zhejiang provincial natural science fundation, No.Y2080258, 2009-1-1 to 2010-12-31

PAPERS ISSUED IN RECENT YEARS:
1. Zhang W, Zhang XZ, Tian CJ, Wang T, Sarkis PTN, Fang YM, Zheng S, Yu XF and Xu RZ. Cytidine deaminase APOBEC3B interacts with heterogeneous nuclear ribonucleoprotein K and suppresses hepatitis B virus expression. Cellular Microbiology. 2008;10(1):112-121. (IF=5.07)
2. Xu RZ, Zhang XZ, Zhang W, Fang YM, Zheng S and Yu XF.（co-first author）Association of human apobec3 cytidine deamineases with the generation of HBx mutants and hepatocellular carcinoma. Hepatology. 2007;46(6):1810-1820. (IF=10.446)
3. Tian CJ，Yu XH, Zhang W, Wang T, Xu RZ, Yu XF. Differential Requirement for Conserved Tryptophans in Human Immunodeficiency Virus Type 1 Vif for the selective suppression of APOBEC3G and APOBEC3F. Journel of Virology. 2006;80(6): 3112-3115. (IF=5.178)
4. Zhang W, Zhang XZ, Fang YM, He ZW, Ying SC, Xu RZ and Yu XF. Cytidine deaminase APOBEC3G may suppress HBV replication through G to A mutation of HBV X gene region. Chin J Microbiol Immuno. 2007;27(2):135-139.
5. Liang Y, Zhou R, Zhang W, Zhang HL, Xu HD, Mao ZR. Analysis of immunoglobulin VH genes in de novo diffuse large B-cell lymphoma. Chinese Journal of Pathology 2007;36(9):625-626
6. Zhang W, Zhou R, Chen PH, He PS. Expression of Caspase-3, Bcl-2 and its relation with cellular apoptosis and proliferation in Non-Hodgkin’s lymphoma. Chinese Journal of Pathology. 2001;30(6):36-40
7. Zhang W, Zhou R, Chen PH, Yang SY, Zhu YF, Zhang SJ. Detection of expression of Bcl-2, Bcl-XL in non-Hodgkin’s lymphoma by CSA method. Chinese Journal of Hematology. 2001;22(11)：596-597