Profile

Name: Zhou Ren
Date of Birth; Nov 04, 1956
Place of Birth; Zhejiang Province, China
Marital Status; Married
Business Address;
Department of Pathology and patho- physiology/Institute of Pathology and Forensic Medicine,
#388 Yu-Hang-Tang Road, Hangzhou, People’s Republic of China, 310058
Academic Position: Professor of Pathology
Title: Depute Director of Department of Pathology and Patho- physiology
Director of Institute of Pathology and Forensic Medicine
Academic Degrees: M.D.; Ph.D.
Specialty: Pathology
Affiliated Faculty: School of Medicine
Research Interest: Tumor Pathology/Molecular genetics of tumor/Pathology of the hematopoietic and lymphoid proliferative disorders

Tel: +86 571 88208205
Fax: +86 571 88208206
Email: zhouren@zju.edu.cn
Personal Web: pending


Education Career：
1978-1983 as a medical student in Zhejiang Medical University, Medical Bachelor Degree awarded
1985-1988 as a postgraduate in Postgraduate School of Zhejiang Medical University, Master Degree of Pathology awarded
1993-1994 as a visiting scholar in Lubeck Medical University, Germany
1999-2000 as a visiting scholar for cooperation research of Ph.D. Degree in institute of Pathology, Wuerzburg University, Germany
1999-2004 in Zhejiang University School of Medicine, Ph.D. Degree awarded.
200801-200803 as an advance visiting scholar in School of Medicine, University of California in Los Angels

Employment Career:
1983-1990 employed as assistant teacher and pathologist in department of pathology and first affiliated hospital, Zhejiang Medical University.
1990-1994 employed as a lecturer and attending pathologist in department of pathology and first affiliated hospital, Zhejiang Medical University.
1995-1998 employed as associate director, an associate professor and associate chief doctor in department of pathology and first affiliated hospital, Zhejiang Medical University.
2000-2001 employed as depute dean of basic medical faculty and an associate director in department of pathology and patho-physiology, Institute of Forensic Medicine, School of Medicine, Zhejiang University.
2002-2006 appointed as depute dean of basic medical faculty and an associate director in department of pathology and patho- physiology, Institute of pathology and forensic medicine, School of Medicine, Zhejiang University.
2007-now promoted to professor position and associate director in department of pathology and patho-physiology, director in Institute of pathology and forensic medicine, School of Medicine, Zhejiang University.

Research field and Academic interest：
1. Tumor Pathology/Molecular genetics of tumor/Pathology of the hematopoietic and lymphoid proliferative disorders;
2. Forensic Pathology

EDITORIAL BOAROD:
Chinese J Cancer Prevention and Treatment
Chinese J Diag Pathology
Special Reviewer, Chinese J Pathology

MEMBERSHIPS:
Member of National Medical Licence Examination Committee of China
Associate President of Pathologist Association in Zhejiang Province
Medical Examiner of Ministry of Justice. PR China
Standing member and secretary of Zhejiang Society of Pathology
Member of Branching Association of Bio-tissue Bank of Chinese Association of Medicine and Bio-technique National Medical Examination Committee of China
Member of consultative committee of local procurator’s department.

Main Research Projects in executing
1． Research Project: Correlative of Genetic polymorphism of CASPASE gene family with molecular biomarkers of B-NHL pathogenesis. Project code: Y2090167. Funding Period: 2009-2011; Funding Source: Natural Scientific Fund in Zhejiang Province.
2． Research Project: Genetic polymorphism of CASPASE gene family as molecular biomarkers within B-NHL pathogenesis. Project code: 2009C3303; Funding Period: 2009-2011; Funding Source: Research Fund in Zhejiang Province.
3． Research Project: Molecular Characteristics of Thymic Epithelial Tumors and relationship of its pathogenesis. Project code: 2009C3303; Funding Period: 2007-2009; Funding Source: Natural Science Fund of China.

PUBLICATIONS (selected)： (*: corresponding author)
1． ZhaoJing（Jr）, ZhaoJing, Cai Ying-Ying, ,MaoJie, ,Yang Kai-Yan, Chen Guo-Rong，Zhou Ren* The correlation of GC-DLBCL and acquired somatic mutations of the BCL6 first intron in DLBCL, Chinese Journal of pathology 2010;39(4): received
2． Mao ZR, Zhou R, Zhang Xx，Mueller-Hermelink HK，Rosenwald A, Application of gene expression profiling in molecular classification, prognosis and therapy of B-cell lymphoma. Chinese J Pathol 2009;38(11):785-790
3． Mao Zheng-rong, Andreas Rosenwald, Zhang Suo-jiang, Zhou Ren, Hans Konrad Mueller-Hermelink; Clonality analysis and mutation status of IgVH genes in classic Richter's syndrome; Chinese J Pathol; 2008；37（8）：523-528
4． Mao ZR, Rosenwald A, Zhang SJ, Zhou R, Mueller-Hermelink HK; Clonality analysis and mutation status of IgVH genes in classic Richter’s syndrome Chinese J Pathol 2008;37(6):364-370
5． Li Hong-juan, Shi wei, Lu Xiang-yun, Shao Min-hua, Zhou R, Lu da-ru, Yu ying-nian; Study on cellular gene response to low concentration of MNNG in human amnion FL cells by high throughput real-time fluorescent PCR Chinese Journal of Pathophysiology 2007：23（1）：1-6
6． LIANG Yun , ZHOU Ren* , ZHANG Wei , ZHANG Huan-lan , XU Hang-di , MAO Zheng-rong Analysis of immunoglobulin VH genes in de novo diffuse large B-cell lymphoma Chinese Journal of pathology 2007;36(9):625-626
7． Mao ZR, Rosenwald A, Zhang SJ, Zhou R, Mueller-Hermelink HK(2007) Clonality analysis of Richter’s syndrome Journal of Practical Oncology 2007；22（2）：145-149
8． Liang Y, Zhou R*, Zhang W, Zhang HL , Xu HD , Mao ZR (2007) BCL-2/IgH translocation in de novo diffuse large B cell lymphoma, Journal of Practical Oncology 2007；22（3）：232
9． Ye YF, Zhou R*, Mao ZR, Zhang W (2006) A novel microsatellite within intron 8 in caspase10 gene (CASP10) in Chinese of Han nationality, Chinese J Med Genet. 2006；23（1）：16-18
10． Liang Y, Zhou R*，Ye YF, Xie Y; Mao ZR (2005) Bcl-2/JH Translocation in Peripheral Blood Cells of Healthy Chinese Individuals, Chinese J Med Genet. 2005；22（5）：76-78
11． Yang Kai-yan, Yu Kang, Li Jian-min, Chen Guo-rong Huang Ka-te, Zhu Qi-jian, Zhou Ren; Expression and Significance of P73 and P51 mRNA in Breast Cancer; Chinese Journal of Medicine; 2006(86) 1428-1430
12． Yang Kai-yan, Yu Kang, Li Jian-min, Huang Ka-te, Zhou Ren; Expression and Significance of P51 Gene in Breast Cancer; Carcinogenes, Teratogenesis & Mutagenesis; 2006(3)249-251
13． Ye Yue-fang, Zhou Ren*, Xie Yun, Yang Shui-you Detection of Single Nucleotide Polymorphisms and Mutations in Caspase-8,-10 Genes in Non-Hodgkin Lymphomas of Han nationality. Chinese Journal of Hemotology 2006；27（10）：694-696,
14． Ye Yue-fang, Zhou Ren*, Xie Yun, Yang Shui-you, Zhang Wei；Haplotypes of Four Single Nucleotide Polymorphisms in Caspase-8,-10 Genes in Han nationality of Zhejiang Province in China. Chinese Journal of Medical Genetics 2006；23（2）：222-226,
15． Liang Yun, Zhou Ren*，Ye Yuefang; Xie Yun; Yang Shuiyou; Bcl-2/JH Translocation in Peripheral Blood Cells of Healthy Chinese Individuals, Chinese Journal of Medical Genetics 2005；22（5）：76-78,
16． Ströbel P, Zettl A, Zhou R, Starostik P, Riedmiller H, Störkel S, Müller-Hermelink HK, Marx A (2002) Spiradenocylindroma of the kidney. Clinical and genetic findings suggesting a role of somatic mutation of the CYLD1 gene in the oncogenesis of an unusual renal neoplasm. Am J Surg Pathol 26: 119-124.
17． Zhou R, Zettl A, Ströbel P, Wagner K, Müller-Hermelink HK, Zhang S, Marx A, Starostik P.; Thymic Epithelial Tumors can Develop along Two different Pathogenetic Pathways American journal of Pathology 2001; 159(5) 1853-1860
18． Zhang huan-lan, Zhou Ren*, Limitation of PCR approach to the Detection of IgH and TCR Gene Rearrangement in non-Hodgkin’s Lymphoma, Chinese Journal of Pathology 2005;34(5):805-806,
19． Lu Shan-shan, Zhou Ren*, Xu ji-wei; Relationship between prognosis of nasal invested papilloma and human papulomavirus types, Chinese J Otorhinolaryngology and Head Neck Surgery 2005;40(3):195-198,
20． Xie Yun, Zhou R*, Ye Yue-fang, Yang-shui-you and Zhang Wei; Study on the Haplotypes of three Single Nucleotide Polymorphisms in Caspase-3 Gene in Han Nationality of Zhejiang Province in China. Chinese J Medical Genetics 2004;21(6):623-625,
21． Zhang Xiao-fei, Zhou Ren*, Mao zheng-rong，Yang Shui-you; The Preliminary Study of the Detection of IgH Gene Rearrangement in B Cell non-Hodgkin’s Lymphoma and the Application of GelScan Method, Chinese J Pathology 2004;33(6):513-517,
22． Zhang Xiaofei, Zhou Ren*, Yang Youping, Mao Zhengrong, Yang Shuiyou, Zhang Suojiang, Study of Dual Rearrangements of Lymphocytic Antigen Receptor Genes (IgH and TCR genes) in non-Hodgkin’s Lymphoma, Chinese Journal of Hemotology 2004；25（10）：583-587,
23． Lu Shanshan, Zhou Ren, Xu Ji-wei, Wang Qun-ji; Expression of p53、Ki-67 and CD44v6 in nasal inverted papilloma and human papillomavirus types; J Clin Exp Pathol 2004; 20（3）：374-376
24． LU Shan-shan，Zhou Ren，XU Ji-wei; Relationship between prognosis of nasal inverted papilloma and human papillomavirus types; Chinese J Otorhinolaryngol Head Neck Surgery, 2005;40(3)195-198
25． Zhang wei, Zhou Ren*, Chen Pei-hui, Yang Shuiyou, Zhu you-fa, Zhang Suojiang, Study on expression of caspase-3 and bcl-2 proteins and their relations with cell apoptosis and proliferation in non-Hodgkin’s Lymphoma, Chinese J Pathology 2001;30(6):434-438,
26． Zhang wei, Zhou Ren*, Chen Pei-hui, Yang Shuiyou, Zhu you-fa, Zhang Suojiang, Application of CSA approach to detect the expression of Bcl-2、Bcl-xl in non-Hodgkin’s Lymphoma and its significance, Chinese J Hemotology 2001；22（11）：597-598,
27． Zhou Ren, Chen Pei-hui：Investigation of IL-9 mRNA in human peripheral mononuclear cells with anti-sense RNA Probe Chinese J Hemotology 1997;18(12):662
28． Merz H, Malisius R, Mannweiler S, Zhou R, Hartman W. Orsches-chek K, Moubayed P, Feller AC: Immunuo-Max: a maximized immunohistochemcal method for the retrieval and enhancement of hidden antigens. Laboratory Investigation 1995;73(1):149
29． Zhou R, Merz H: Application of a novel method to increase antigen-signal in immuno-histochemistry. Chinese J Histochemical and Cell-chemical 1996;5(3):31
30． Zhou R, Merz H, Yang Sy: Study of AKP substrate –introduction of a novel AKP substrate; Chinese J Histochemical and Cell-chemical 1998;7(1):50
31． Xu Ying-han, Zhou Ren*; Causes of Sudden Death During the Process of Venous Infusion: An Analysis of 12 Cases; J Forensic Medicine 2006；22（6）：1-3
32． Xu Ying-han, Zhou Ren*; Newborn Emphysema Attributed to Medical Actions (3 case report); J Forensic Medicine 2006；22（2）：133-134


Book Contributors:
1. Chief Editor : Lu Yuan , Co-chief Editors: Zhou Ren;《Medical Experiment Course for Basic Medicine 》 Zhejiang University Press 2009;May; Hangzhou, China.
2. As one of editors; 《A Guideline of National Examination for Physician License》 People’s Hygiene Press 2009;Jan,Beijing.
3. Chief Editor : Chen Zhi , Co-chief Editors: Wu Yu-lian, Zhou Ren, Hu Shen-jiang, Xu Li-hong, Xia qiang, Huang He; 《A guideline for National Examination for Postgraduate Access in 2009：Comprehensive Medical Guideline》 Zhejiang University Press 2008;Nov; Hangzhou, China.
4. Chief Editor : Chen Zhi , Co-chief Editors: Wu Yu-lian, Zhou Ren, Hu Shen-jiang, Xu Li-hong, Xia qiang, Huang He; 《A guideline for National Examination for Postgraduate Access in 2008：Comprehensive Medical Guideline》 Zhejiang University Press 2007;Nov; Hangzhou, China.
5. Chief Editors : Xu Ying-han, Lai Maode, Zhou Ren; 《Practical Forensic Pathology: 100-case Analysis》 High Education Press, 2006;Aug,Beijing, China.
6. Chief Editor : Chen Ji-Qiang , Co-chief Editors: Ling Shu-cai, Zhou Ren, Yang You-jin, Xia Qiang;《Human Morphology Experiment Course 》 Zhejiang University Press 2006;June; Hangzhou, China.
7. As one of Editors:Zhou Ren 《Pathology》 3rd Edition, Fudan University Press,2005,Oct,Shanghai, China.
8. As one of Editors:Zhou Ren. 《Basic Medicine Course: General Part》 Science Press,2004;Aug.Beijing.
9. As one of Editors:Zhou Ren 《Basic Medicine Course: Systemic Part》 Science Press,2004;Aug.Beijing.
10. Chief Editor : Xu Ying-han , Co-chief Editors: Zhou Ren, Yang Zeran 《Pathology: Questions and Answers》 Zhejiang University Press 2003; Hangzhou, China.
11. As one of Editors: Zhou Ren;《Anatomic Pathology》;Hangzhou University Press 1998; Hangzhou, China.
12. As one of Editors: Zhou Ren; 《Chinese Surgical Pathology》People’s Hygiene Press, 1st edition, 2002;Aug,Beijing.
13. As one of Editors: Zhou Ren; 《Modern Ischemic Cardiac Diseases》, Military Physician Press,1st edition, 2000,Beijing.
14. As one of Editors: Zhou Ren;《Enviromental Pathology》, The World Book Company,1994, Beijing.

Honors and Awards
（1）Scientific Awards
2008, Scientific Award in 3rd Class issued by the Government in Zhejiang Province: Application of Clonic arrangement of IgH and TCR genes in Molecular Diagnosis of NHL, Award code: 0803226-1

2004, Excellent Ph.D. Theme issued by Zhejiang University Authority, Approval code: [2005]03

1995, Scientific Award in Excellent Class issued by the Government in Zhejiang Province: The Relationship of Air Pollution and the pathogenesis of pulmonary cancers,

（2）Education Awards
Chen Ji-Qiang, Xia Qiang, Lu Yuan, Hu Xiao-jun, Zhou Ren, Ling Shu-cai
2009, University Education Award in 1st class issued by the Government in Zhejiang Province: Innovation and Practice on Integrated Medical Course

Zhou Ren (Course Director)
2008, National Excellent Course: Pathology, issued by Ministry of Education in China, Approval code: [2008]22

Chen Ji-Qiang, Xia Qiang, , Zhou Ren, Ling Shu-cai, Yang You-jin
2008, Education Award in 1st class issued by Zhejiang University: Innovation and Practice on Integrated Medical Course

Zhu Ke-qin, Zhou Ren, Chen Jian, Zhang Wei.
2008, Education Award in 2nd class issued by Zhejiang University: The Practice of Clinical Pathological Conference
Zhou Ren (Course Director)
2006, Excellent Course for Medical Graduates, awarded by Zhejiang University

Chen Ji-Qiang, Xia Qiang, , Zhou Ren , Yang You-jin
2004, Education Award in 1st class, issued by Zhejiang University: Practice on Integrated Basic Medical Course