Histology and Embryology
Course Number:18121730
Prerequisites: Cell biology
Credits (hours per week, Lecture/Practical): 4.5 (3-3)
Year: 1st year
COURSE DESCRIPTION:
Histology is the branch of science that centers on the biology of cells and tissues within an organism and, as such, serves as the foundation on which pathology and pathophysiology are built. This course will cover the basic facts and interpretation of microscopic anatomy. Tutorials and laboratories will emphasize problem-solving skills, integration of knowledge and independent learning. The laboratories will provide training in basic histology techniques and an understanding of the cells and tissues of the human body system.
Embryology provides an overview of early development from gametogenesis through the embryonic period; also included in this section are chapters on placental and fetal development and prenatal diagnosis and birth defects.
OBJECTIVES:
Histology: Students should gain an understanding of 1) the concepts of human body structure, 2) mechanisms of the tissue, organ and system working; and 3) the most important recent developments in the sciences basic to histology. The laboratories will provide training in basic histology techniques and an understanding of the cells and tissues of the human body system.
Embryology: Students should gain an understanding of 1) the clinical significance of embryology; 2) which is essential in the diagnosis and prevention of birth defects; 3) recent advances in genetics, developmental biology, maternal-fetal medicine.
COURSE CONTENT:
Lecture (48 hrs):
1. Introduction 1hr
1.1 Light microscopy
1.2 Electron microscopy
1.3 The cytoplasm
2. Epithelial tissue 2hr
2.1 The forms and characteristics of epithelial cells
2.2 Specializations of the cell surface
2.3 Types of epithelia
3. Connective tissue 3hrs
3.1 Cells of the connective tissue
3.2 Fibers
3.3 Types of connective tissue
4. Cartilage 1hrs
4.1 Hyaline cartilage
4.2 Elastic cartilage
4.3 Fibrocartilage
5. Bone 2hrs
5.1 Bone cells
5.2 Bone Matrix
5.3 Types of bone
5.4 Bone growth and remodeling
6. Nerve tissue 3hrs
6.1 Neurons
6.2 Axon
6.3 Galia cells and neuronal activity
6.4 Nerve fibers
6.5 Nerves
6.6 Ganglia
7. Muscle tissue 2hrs
7.1 Skeletal muscle
7.2 Cardiac muscle
7.3 Smooth muscle
8. Blood 2hrs
8.1 Composition of plasma
8.2 Erythrocytes
8.3 Leukocytes
8.4 Lymphocytes
8.5 Monocytes
8.6 platelets
9. The circulatory system 2hrs
9.1 Capillaries
9.2 Arterioles
9.3 Veins
9.4 Heart
10. Skin 2hrs
10.1 Epidermis
10.2 Dermis
10.3 Hairs
10.4 Glands of the skin
11. The immune system and lymphoid organs 2hrs
11.1 Thymus
11.2 Lymph nodes
11.3 Spleen
11.4 Mucosa-associated lymphoid tissue
11.5 Tonsil
12. Digestive tract 2hrs
11.1 General structure of the digestive tract
11.2 Esophagus
11.3 Stomach
11.4 Small Intestine
11.5 Large intestine
11.6 Appendix
13. Organs associated with the digestive tract 2 hrs
13.1 Salivary gland
13.2 Pancreas
13.3 Liver
13.4 Gallbladder
14. The respiratory system 2hrs
14.1 Trachea
14.2 Bronchial tree
14.3 Pulmonary blood vessels
15. The urinary system 2hrs
15.1 Kidneys
16. Endocrine system 2hrs
16.1 Hypophysis
16.2 Adrenals
16.3 Thyroid
17. The male reproductive system 2hrs
17.1 Testis
17.2 Accessory Genital Glands
18. The female reproductive system 4hrs
18.1 Ovaries
18.2 Oviducts
18.3 Uterus
18.4 Vagina
18.5 Mammary glands
19. Sense organ 2hrs
19.1 eye
19.2 ear
20. General embryology 4hrs
20.1 Gametogenesis: conversion of germ cells into male and female gametes
20.2 First week of development: ovulation to implantation
20.3 Second week of development: bilaminar germ disc
20.4 Third week of development: trilaminar germ disc
20.5 Third to eight week: the embryonic period
20.6 Third month to birth: the fetus and placenta
20.7 Birth defects and prenatal diagnosis
21. Special embryology 4hrs
21.1 Cardiovascular system
21.2 Digestive system
21.3 Head and neck
21.4 Urogenital system
Laboratory (48hrs) 3hrs/time
1. Introduction, Epithelium
2. Connective tissue
3. Cartilage, Bone, Blood
4. Muscle tissue
5. Nervous tissue
6. Circulatory system
7. Immune system
8. Skin, Digestive tract
9. Digestive gland
10. Respiratory system
11. Urinary system
12. Male reproductive system
13. Female reproductive system
14. Sensory system
15. Review
16. Lab test
STRUCTURE:
The course comprises 48 hrs of lectures and 48 hrs of practicals.
One weekly 3hrs lecture will be held.
One weekly 3 hr practical session will be held.
ORGANIZATION:
Each session will be offered to the entire class.
An assistant will act as liaison between students and teachers, and will be responsible for taking attendance, collecting exam papers, and related matters.
EVALUATION:
Written examination 60- 70%
Lab test 20-30%
Class performance 5-10%
RECOMMENDED TEXTBOOK:
Basic Histology: Text & Atlas, 10th Edition, Luis Carlos Junqueira; Jose Carneiro; Paperback.
Langman's Medical Embryology, 9th Edition, Thomas Sadler,
SUPPLEMENTARY READING:
three Other suitable texts that are in the book store are those by: Junqueira & Carneiro; Ross; and Stevens and Lowe.
TEACHING TEAM:
Faculty:
Prof. Li Jicheng
Tel: 88208088
Email: lijichen@zju.edu.cn
Associate Prof. Zhou Jun
Tel: 88208255
Email: zhjjwm300@zju.edu.cn
Associate Prof. Ding Shiping
Tel: 88208023
Email: dingshiping@zju.edu.cn
Associate Prof. Yang Youjing
Tel: 88208023
Email: yyoujing@zju.edu.cn
Dr.Xu Weizhen
Email: xwztjf@zju.edu.cn
Dr. Li Zhongjie
Email: lizhongjie@zju.edu.cn
Dr. Zhang Ling
Email: zhangling71@163.com
Dr. Song Ying
Email: sying@zju.edu.cn