Stem cell-based therapy to treat liver diseases is a focus of current research.Cell types and the transplantation pathways are the key facto...
Signaling via the Akt serine/threonine protein kinase plays critical roles in the self-renewal of embryonic stem cells and their malignant c...
The development of cortical inhibitory circuits is closely associated with neuropsychiatric disease as schizophrenia. But the understanding ...
The emergence of multidrug-resistant Gram-negative bacteria, in particular Acinetobacter baumannii and Pseudomonas aeruginosa, is a critical...
Neuronal histamine is presumed to play a major role in regulating diurnal fluctuations such as sleep-wake rhythm. There were, however, no da...
The expression of histamine receptor 1-4 (H1- 4R) and histamine methyltransferase was determined in the histamine projection areas which are...
Schizophrenia is one kind of severe neuropsychiatric diseases which affect almost 1% of the world population. But the pathological mechanism...
Human health has been challenged by multidrug resistant microorganisms for several decades. Herein, we have developed a main-chain imidazoli...
Professor Chao He and his group firstly compared the secretome of fresh cultured CRC tumor tissues and paired normal colorectal (NC) tissues...
In postmortem brain material of preclinical Parkinson’s disease (PD), clinical PD, and control subjects, we determined with quantitati...
Epilepsy is a disabling neurological disorder that affects about 1% of the general population of all ages. About 30% of affected individuals...
ADP is a key platelet agonist responsible for platelet aggregation and thrombus stability in vivo. Our recent finding indicated that ADP sti...
Recently, the research of Chao He and his team from Sir Run Run Shaw Hospital, cooperated with Shanghai Jiaotong University, was published i...
The body's immune system relies on a spectrum of highly differentiated immune cells to combat external microbial infections. Among whi...
The Pictet−Spenglerase strictosidine synthase (STR1) has been recognized as a key enzyme in the biosynthesis of some 2000 indole alkal...