Profile

Name: Hui Chen
Gender: Female
Position: Professor, Director
Address: Dept. of Periodontics and Conservative Dentistry,Affiliated Hospital of Stomatology , Medical college, Zhejiang University, Hangzhou 310031, P. R. China
Tel. 0086-571-87217437 Fax: 0086-571-87217433
E-mail: Huic66@hotmail.com

Interested Research Fields:
1. Oral biofilm
2. Oral infection and systemic disease . (Oral bacteria, proinflammatary cytokines and coronary heard disease )
3. Clinical study of direct restoration of light cure composite


Training & visiting & Scholarship：

01.2007—02 .2007 Dental School, UCLA, US. Grant of Zhejaing government
08,2006— 9.2006 Dental School, UBC, CA Grant of Zhejaing government
08.2004—11.2004 Dental School, Kiel University, Kiel, Germany
Grant of DAAD.and CSC
01.2002--- 01.2003. Grant of the Chinese Academic Exchange Service, CSC )
Dept. of Periodontics and Conservative Dentistry, Dental School,
Kiel University, Kiel, Germany
10.1993 - -07.1994. University Academic Exchange Program,
Dept. of Periodontics and Conservative Dentistry, Dental School,
Kiel University, Kiel, Germany

Education
09.1985-07,1988 Master of Science, Faculty of Stomatology ,
Capital University of Medicine , Beijing, China
03.1978. –07.1982 Bachelor of Science, Faculty of Stomatology,
Zhejiang Medical University, Hangzhou, China

Experience
2001- present Director , Professor & dentist ,
Dept. of Conservative Dentistry and periodontics , Affiliated Hospital of Stomatology, Medical College, Zhejiang University Hangzhou, zhejiang. PRC
1995- 2001 Director , Associate Professor & dentist ,
Dept. of Conservative Dentistry and periodontics , Affiliated Hospital of Stomatology, Medical College, Zhejiang University Hangzhou, zhejiang. PRC
1990-1995 Lecturer & Dentist
Department of Conservative Dentistry and periodontics, Faculty of Stomatology, Zhejiang Medical University, Hangzhou, China
1988-1990 Assistant & Dentist,
Dept. of Conservative Dentistry and periodontics , Affiliated Hospital of Stomatology, Medical College, Zhejiang University Hangzhou, zhejiang. PRC
1982-1985 Dentist ,
Department of Dentistry, Jiaojiang Hospial, Jiaojiang , Zhejiang, China

Projects:
1. 2004—2006 science and technology Department of zhejiang Province 2004c34011 100,000(Yuan)
Platelet Activating Factor Levels of Serum and Gingival Crevicular Fluid in Patients with Coronary heart Disease and Patients with Periodontitis
2. 2005—2006 Natural Science foundation of Zhejiang province 205009 30,000(Yuan)
Homocysteine level of Serum and Gingival Crevicular Fluid in Patients with Coronary heart Disease and Patients with Periodontitis
3. 2007---2009 science and technology Department of zhejiang Province J30490
The role of Gingipain (RgpA/ RgpB/ Kgp) on the human artery endothelial cell and the production of the gingipain monoclonal antibody from BALB/C mice
200,000 (yuan)
4. 2007—2009 China petrochemical cooperation foundation 160,000(yuan)
Investigation of periodontitis and chronic inflammation agents in GCF and serum in population living in Zhenhai area


Publication

Jiayan He, Wujing Huang, Zhiwen Pan, Honghua Cui, Ganggang Qi, Xueping Zhou ，Hui Chen. Quantitative analysis of microbiota in saliva, supragingival, and subgingival plaque of Chinese adults with chronic.periodontitis. Clin Oral Investig. 2012 Dec;16(6):1579-88 ( IF: 2.25)

Tu Y, Huang W, Pan Z, Hu H, Chen H. Effect of Streptococcus sanguinis/Porphyromonas gingivalis single and combined biofilms upon platelet aggregation. Oral Dis. 2012 Sep;18(6):586-94.（IF: 2.14）

Xinyu Zheng, Jinhao Hu, Yadong Chen, Yunjie Zhu, Hui Chen. AFM Study of the Effects of Collagenase and its Inhibitors on Dentin Collagen Fibrils. Journal of Dentistry 2012，40（2）：163-171. （IF: 2.11）

H. H. Zhua, Q. G. Chenb, B. Linc, d, and H. Chen. Study of validity of Autofluorescence-based incipient occlusal caries detection in vitro compared to DIAGNO Dent pen. Laser Physics. 2012, 22(3):1-6. ( IF: 1.31 )

X. ZHENG, H. PAN Z. WANG, H. CHEN. Real-time enzymatic degradation of human dentin collagen fibrils exposed to exogenous collagenase: an AFM study in situ. Journal of Microscopy. 2011 Feb. 241（2,）：162–170. （ IF: 1.87 ）

Chen H, Zheng P, Zhu H, Zhu J, Zhao L, El Mokhtari NE, Eberhard J, Lins M, Jepsen S. Platelet-activating factor levels of serum and gingival crevicular fluid in nonsmoking patients with periodontitis and/or coronary heart disease. Clin Oral Investig. 2010 Dec; 14(6):629-36. (IF: 2.25)

Ling Z, Kong J, Jia P, Wei C, Wang Y, Pan Z, Huang W, Li L, Chen H,Xiang C. Analysis of Oral Microbiota in Children with Dental Caries by PCR-DGGE and Barcoded Pyrosequencing. Microbial Ecology. 2010 Oct;60(3):677-90. (IF: 3.25)

Q.G. Chen,B. Lin,Z.B. Chen,H.H. Zhu ,H. Chen. Pilot study on early detection of dental demineralization based on laser induced fluorescence. Laser Phys Lett .2010 (7)10 ; 752–756. （IF: 6.01）

Shuli Deng, Søren Jepsen , Henrik Dommisch , Meike Stiesch, Helmut Fickenscher , Edmund Maser , Hui Chen , Jörg Eberhard. Cysteine proteases from Porphyromonas gingivalis and TLR ligands synergistically induce the synthesis of the cytokine IL-8 in human artery endothelial cells. Arch Oral Biol. 2011 Dec;56(12):1583-91. （IF:1.4）

Zhang Jie, Cui Hong-hua,Zhang Qi-xia,Han Shu-guang,Chen Hui.Cloning and expression of Hgp44 from Porphyromonas gingivalis. Chin J Stamotol.2011:46(12):735-739

PAN Heng-biao,CHEN Hui,ZHOU Na,JIN Dan,ZHANG Jing,PENG Chun-meil．Relationship between periodontitis and levels of hiIgh-sensitivity C-reactive protein.West China JournM of Stomatology,2010:28(4).



Zheng X, H. Pan, H. Chen: Atomic Force Microscopy Study Of Human Dentin Collagen Fibrils J. Dent. Res. 88 Spe.Iss B , Oct. 88, 2 009，113

H. Chen, Q. Xi, Renate, W. Shi:Inhibitation of Xipayi mouthrinse on bacteria in vivo and vitro, Dent. Res. 88 Spe.Iss A , Mar. 88, 2 009，1554


Tu, H. Chen. Platelet Adhering to Streptococcus sanguis Surface under imitating flow system. IADR, 2009, #2882.

N Zhou, H. Chen. periodontal disease and elevated serum high-sensitivity C-reactive protein levels. IADR, 2009, #3480.

Y Wang, A . Zhang, H. Chen : Experimental study of effects of fluoride on expression of TGF-β1 of human tooth germ cultured in vitro Stomatology， 29（11）2009
Yu Jinjin Chen H Periodontitis and preterm low-birthweight infant. International Journal of Stomatology ,2008(4) 35(Suple) 109-111

Chen H, Zhu H , Li X, Sun W , Zhang F,. Survey of the current situation on clinical application of root canal treatments in Zhejiang province. Shanghai Journal of Stomatology. 2007（1）11-14

Sun W, Chen H, Li X. Examination and analyses of oral hygiene care knowledge in gestation. Stomatology，2007（7）375-376,379

Zheng P, Chen H, Shi S, Jepsen S, Eberhard J. Periodontal parameters and plateletactivating
factor levels in serum and gingival crevicular fluid in a Chinese population. J Clin Periodontol 2006; 33: 797–802.

Li X, Kong J, Chen H, Liang F, He J. Associations between periodontal status and delivery outcomes in pregnant women with a diagnosis of threatened premature labor. Chinese Journal of Stomatology 2006（10）599-601
Li X, Kong J, Chen H, Liang F, He J, A Pilot Study on Relationship of Periodontal Status, Serum Level of Interleukin-1β and Delivery Outcomes in Pregnant Women. West China Journal of Stomatology. 2007（1） 61-63
Li X, Kong J, Chen H, Liang F, He J . Analysis of periodontal status in pregnant women with a diagnosis of threatened premature labor. Shanghai Journal of Stomatology. 2006（05）478-481

SL. Shi, H Chen, Periodontal tissue conditions’relationship to Homocysteine Levels in peripheral blood .The 6th Annual meeting of IADR Chinese division P 189 ,2005

P. Zheng， H. Chen ,:Periodontal tissue conditions relationship to CRP level in peripheral blood . The 6th Annual meeting of IADR Chinese division P188 .2005

H. Chen , P. Zheng :The Relationship Between the Volumes of Gingival Crevicular Fluid and Periodontal Inflammation . The 6th Annual meeting of IADR Chinese division P189 ,2005

H. Chen , P. Zheng : PAF in gingival crevicular fluid and serum correlate with periodontitis J. Dent. Res. 84 Spe.Iss A , Mar,2 005

H. Chen , JM．Huang ，HK　Albert ., 　Adhesion of Streptococcus Mutam to composite resin with Sealant surface .J. Dent. Res. 84 Spe.Iss A , Mar, 2 005

H. Chen , SL. Shi , Homocysteine Levels in GCF and Serum in Periodontal Patients. J. Dent. Res. 83 Spe.Iss A , Mar,2 004

H Chen , JP Chen ：Applying Vitapex in Root Canal Filling for Apical Periodontitis with Apparent Indications for Endodontic Surgery. J. Dent. Res. 83 Spe.Iss B , Jun, 2 004

P, Zheng , H Chen , Relationship between sulfide level and severity of periodontal disease. J. Dent. Res. 83 Spe.Iss B , Jun, 2 004
H Chen , W Zhang :Coronary heart disease and Streptococcus Sanguis group (a case control study in China. ) J. Dent. Res. 82 Spe.Iss A , June ,2 003

Chen H, Deng S, Zhu J, zhao L. Distribution of Streptococcus Sanguis group in Oral cavity with coronary Heard Disease. Chin J Microbiol Immunol, 2003, 23(2) 108

Zhao, LL; Zhu, JH; Deng, SL; Zhang, WD; Qiu, YG; Chen, H. Relationship between oral infections and coronary heart disease. Chin J Cardiol,2003;31(3):195-197

Zhang W, Chen H, Yu Z. Influence of different DNA extractions on the identification of Streptococcus Sanguis group by arbitary primed polymerase chain reaction . J. Zhejiang Univ ( Medical Sci) 2002, 31(6) 464

Hui Chen , Weidong Zhang. Streptococcus Sanguis group in oral cavities of coronary heard disease patients. J Dent. Res. 2002, 81(spp) 3877

Shi Y, Zhang W, Chen H. Arbitrary primed polymerase chain reaction for the genotypic identification of Streptococcus sanguis group Shanghai Kou Qiang Yi Xue. 2003 Feb;12(1):21-3.

Deng S, Chen H, Zhang W. The relativity between Streptococcus Sanguis group and coronary Heard Disease .Chin J Stomato, 2002, 37(3) 184

Chen H, Zhao M, Li J, Deng S. Effect of Streptococcus Sanguis on blood composition, blood Pressure and cardiac dysfunction in rabbis . Chin J Stomato, 2001, 36(5) 354

Zhang W, lai A, Chen H, Li J. Applying RA-PCR in identifying Streptococcus Sanguis group Chin J lab Med 2002 25(3) 169

Chen H, shao Y, Deng S. Reducing Bacterial Aerosols by Ultrasonic Scaling with Koutai or 1.5% H2O2 pre-rinse. Chinese Journal of Stomatology 2000,36(5) 381

Chen H, Zhao S.The Technique of Hard Tissue Section for the Histology Study of HA-coated Implants. Journal of Zhejiang University ( Medical Science ) 1999,2894): 174

Chen H, Gu h, Chen Z, Ma X.Comment on Oral microbiology Education in China .Chinese Journal of Higher Medical Education 1999,67(1) 36

Chen h, Jiang j, Wang q. Clinical Evaluation of Root Canal Filling by Using Vitapex. Chinese Journal of Conservative Dentistry 1999,9(supple) 153--154

Chen H, Chen X, Wu Q. Inhibitionof lanthanum and Cerium on Streptococus Mutan .Chinese Journal of Microecology 1999, 11(5): 307

Chen H, Wu Q, Chen X. Inhibitionof lanthanum on Streptococus Mutan .Chinese Journal of Dental Materials and Devices 1999,8(3) 133

Chen H, Zhu F, Wu Y, Peng C, Xing x, Chen S, Yang M. Clinical and Laboratory Study of Propolis Alcoholicextract Disinfecting Infected Root Canal. Chinese Journal of microecology 1996,8(2) 40

Chen H, Zhu F. Clinical Evaluation of Propolis Alcoholicextract Disinfecting Infected Root Canal
Chinese Modern applying medication 1996, 30(50)

Chen H, Wu Q, Chen x. Propolis Alcoholicextract Inhibition on infected root canal Bacteria
Chinese Journal of Dental Materials and Devices 1996,8(3) 133

Chen H, Yang S, Su Z, Zhang C, Ren L, Li J, Guo Y.. Selection of Chinese Herbs on Their Antimicrobial properties against anaerobic Bacteria Isolated from Infected Pulp Canal
Journal of Modern Stomatology 1993,7(2)

Chen H, Yang S, Su Z, Zhang C, Ren L, Li J, Guo Y. Identifying Bacteroides Endodontalis by Indirect Immune Fluorescence
Stomatology 1993,13(1)

Chen H, Su Y, Yang S. An Electron Microscopic Survey of the surface structures of Oral Black-pigmented Bacteroides
Chinese Journal of microecology 1992, 4(2)

Chen H, Yang S, Su Z, Zhang C, Ren L, Li J, Guo Y.Identifying Bacteroides Endodontalis by G+C Content and DNA-DNA Hybridization Study
Chinese Journal of Conservative Dentistry 1992,2(3)

Chen H, Yang S, Su Z, Zhang C, Ren L, Li J, Guo Y. Isolation and Identification versus Direct Immunofluorescence Test of Specimen Containing Bacteroides endodontalis
Chinese Journal of Microecology 1990,2 (2)

Chen H, Su Y, Yang S, Gu Z. The Correlation of Black-pigmented Bacteroides spp to Symptoms Associated with apical periodontitis
Chinese Journal of Stomatology 1990,26(2)