Profile

Name: Xiao-Ming Zhu

Titles: Chief Physician and Associate Professor

Degrees / Designations: PhD & M.D.

Email: ntzhuxm@hotmail.com
Phone: 0086-571-8706-1501-1832
Fax: 0086-571-8706-1878
Address: Women's Hospital, School Of Medicine, Zhejiang University, 1 Xue-shi Rd, Hangzhou City, Zhejiang Province, 310006, China

Research Areas:
1.Reproductive aging & Assisted reproductive techniques
2.Safety of Assisted reproductive techniques
3.Techniques for autologous embryonic stem cells

Current Projects
1.Operating: The dynamic investigation of genomic imprints expression profiles and changes of assisted conceptions and the related mechanisms, granted from The National Natural Science Fund of China (2007-2009)
2.Participating: Role of oocyte-derived growth factors in human ovarian follicle development, granted from China-Canada Joint Health Res (2008-2010)
3.Participating: Research on reproductive aging-related issues in fertility and population health and their mechanisms, granted to MOST-CIHR Team in Reproductive Aging from China-Canada Joint Health Res (2010-2012)

Selected Publications
1.He RH, Gao HJ, Li YQ, and Zhu XM, The associated factors to endometrial cavity fluid and the relevant impact on the IVF-ET outcome. Reprod Biol Endocrinol, 2010. 8(1):46

2.Li Tang, Yu Zhang, Hong Pan, Qiong Luo, Xiao-Ming Zhu, Min-Yue Dong, Peter C. K. Leung, Jian-Zhong Sheng and He-Feng Huang: Involvement of cyclin B1 in progesterone-mediated cell growth inhibition, G2/M cell cycle arrest, and apoptosis in human endometrial cell. Reproductive Biology and Endocrinology 2009, 7:144

3.Lin K, Zhu X, Xu H, Liang Z, Zhang X: Reproductive outcome following resectoscope metroplasty in women having a complete uterine septum with double cervix and vagina. Int J Gynaecol Obstet. 2009;105(1):25-8

4.Zhu X M, Zhu Y M, Huang H F, et al: Autologous mature follicular fluid: its role in in vitro maturation of human cumulus-removed oocytes. Fertil Steril, 2008; 90(4):1094-102.

5.Yan-Ting Wu, Li Tang, Jie Cai, Xiu-E Lu, Jian Xu, Xiao-Ming Zhu, Qiong Luo and He-Feng Huang: High bone morphogenetic protein-15 level in follicular fluid is associated with high quality oocyte and subsequent embryonic development. Hum Reprod, 2007, 21(6):1526-31

6.Ai-Xia Liu, Yi-Min Zhu, Qiong Luo, Yan-Ting Wu, Hui-Juan Gao, Xiao-Ming Zhu, Chen-Ming Xu and He-Feng Huang: Specific peptide patterns of follicular fluids at different growth stages analyzed by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry. Biochim Biophys Acta, 2007, 1770(1):29-38

7.Luo Q, Ning WX, Wu YT, Zhu XM, Jin F, Sheng JZ, Huang HF, Altered expression of interleukin-18 in ectopic and eutopic endometrium of women with endometriosis. J Reprod Immunol 2006; 72:108-17

8.Luo, Q., Yang, J., Zeng, Q. L., Zhu, X. M., Qian, Y. L., Huang, H. F.: 50-Hertz electromagnetic fields induce gammaH2AX foci formation in mouse preimplantation embryos in vitro. Biol Reprod. 2006; 75:673-80

9.Jin L, Zhu X M, Huang H F, et al: A novel SNP at exon 17 of the INSR gene is associated with decreased insulin sensitivity in the Chinese women with PCOS. Mol Hum Reprod 2006, 12(3):151-155.

10.Ruan H C, Zhu X M, Huang H F., et al: Ovarian stimulation with GnRHa, but not GnRHant, might restore the expression of endometrial integrin β3 and leukemia inhibitory factor and improve uterine receptivity in mice. Hum Reprod, 2006, 21(10):2521-2529

11.Leung PC, Cheng CK, and Zhu XM, Multi-factorial role of GnRH-I and GnRH-II in the human ovary. Mol Cell Endocrinol, 2003, 202:145-53

12.Lau H.L., Zhu X.M., Leung P.C., et al., Detection of mRNA expression of gonadotropin-releasing hormone and its receptor in normal and neoplastic rat prostates. Int J Oncol, 2001, 19:1193-201