||Director of Dept. of dermatology
||Dermatology and Venereology
||The Affiliated Sir Run Run Shaw Hospital
||The biological prevention of sexually transmitted disease
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Professor Cheng is a director of department of dermatology of Sir Run Run Shaw Hospital. She teaches dermatology，Venereology，and Rheumatology to undergraduate and graduate students of the University. She has been appointed as an editor for several medical journals.
Her research is focused on the study of defining pathogenesis and developing therapeutic approaches of some skin disease, such as HPV infection, allergic disease, and autoimmune disease. The broad interest of her laboratory is the investigation of the interactions between HPV and their hosts at a molecular and immune level. Professor Cheng has also pursued her interest in T cell function in autoimmune disease. She is particularly interested in pursuing novel treatments for HPV infections, skin allergy and autoimmune disease. She holds many research funding from NSFC, and provincial government.
(1) Chen XZ, Zhu KJ, Xu Y, Tang XY, Cai XZ, Zhang X, Cheng H.RNA interference silences the human papillomavirus 6b/11 early gene E7 in vitro and in vivo. Clin Exp Dermato. 2009 Oct 23. [Epub ahead of print]
(2) K-J Zhu, J-P Cen, J-X Lou, Q Wang, X Zhang, Y Xu, X-Z Chen, H Cheng. Imiquimod inhibits the differentiation but enhances the maturation of human monocyte-derived dendritic cells. International Immunopharmacology. Volume 9, Issue 4，April 2009, Pages 412-417
(3) Zhu K, He F, Jin N, Lou J, Cheng H. Complete atrioventricular block associated with dapsone therapy: a rare complication of dapsone-induced hypersensitivity syndrome. Journal of Clinical Pharmacy and Therapeutics (2009) 34, 489–492
(4).Chen XZ, Mao XH, Zhu KJ, Jin N, Ye J, Cen JP, Zhou Q, Cheng H.Toll like receptor agonists augment HPV 11 E7-specific T cell responses by modulating monocyte-derived dendritic cells. Arch Dermatol Res. 2009 Jul 4. [Epub ahead of print]
(5)Y Xu, K-J Zhu, N Zhu, D-H Jiang, X-Z Chen and H Cheng. Expression of Foxp3+CD4+CD25+ regulatory T cells and Th1⁄Th2,Tc1⁄Tc2 profiles in the peripheral blood of patients with condyloma acuminatum. Clinical and Experimental Dermatology. 2009; Mar 34(2) :,229–235 34229-35,
(6)Xu Y, Zhu KJ, Chen XZ, Zhao KJ, Lu ZM, Cheng H. Mapping of cytotoxic T lymphocytes epitopes in E7 antigen of human papillomavirus type 11. Arch Dermatol Res. 2008 Jun;300(5):235-42.
(7)Zhu KJ, Zhou Q, Lin AH, Lu ZM, Cheng H. The use of intravenous immunoglobulin in cutaneous and recurrent perforating intestinal Degos disease (malignant atrophic papulosis). Br J Dermatol. 2007 Jul; 157(1):206-7.
(8)Zhao KJ, Cheng H, Zhu KJ, Xu Y, Chen ML, Zhang X, Song T, Ye J, Wang Q, Chen DF. Recombined DNA vaccines encoding calreticulin linked to HPV6bE7 enhance immune response and inhibit angiogenic activity in B16 melanoma mouse model expressing HPV 6bE7 antigen. Arch Dermatol Res. 2006 Jul;298(2):64-72.
(9) Zhu K, Cheng H, Mao X, et al. Increased endocytic activity in monocyte-derived dendritic cells in patients with psoriasis vulgaris. Indian J Med Res 2006; 123(1):43-50