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基本信息:

姓名: 夏旸
职务:
职称:
学历: 博士
专业: 内科学(呼吸病)
所属院系: 浙医二院
研究方向: 介入呼吸病/肺癌/慢性气道疾病
电话:
信箱: yxia@zju.edu.cn
个人主页: http://person.zju.edu.cn/yxia

个人简介:

  夏旸博士曾在Johns Hopkins医学院完成系统的临床及科研训练,专注慢性气道疾病、肺癌及介入呼吸病技术。目前共发表SCI论文18篇,其中以第一作者/通讯作者在NEJMLancetJAMAHypertension等权威医学期刊发表12篇,累计影响因子近200分。主持国家、省部及厅局级科研项目6项,参加国家重大研究专项、重大项目、重点国合等6项。以第一发明人申请国家专利6项,已授权3项。参编专著《可弯曲支气管镜技术》,并受邀撰写美国介入呼吸病教科书《Flexible Broncoscopy 4th edition》气道狭窄章节。获德国诺贝尔奖获得者委员会青年科学家奖、浙江省医坛新秀等荣誉称号。担任中国医师协会全国青委、中国医师协会内镜分会青委常委、海医会介入专委会委员、浙江省医学会呼吸病分会呼吸介入学组委员等职。目前已独立培养硕士研究生2名,辅助培养博士研究生名。


代表性论著:

期刊论文

1.  Xia Y, Li W, Shen H: Mepolizumab for Eosinophilic COPD. New England Journal of Medicine 2018; 378:680-683. (IF:72.41)

2.  Xia Y, Cao C, Li W, Shen H: Severe asthma and asthma-chronic obstructive pulmonary disease

syndrome. Lancet. 2016 Dec 3;388(10061):2741-2742.(IF:44.02)

3.  Xia Y, Xia L, Shen H. SMART in the management of patients with persistent asthma. JAMA. (accepted) (IF:44.405)

4.  Xia Y, Yang XR, Fu Z, Paudel O, Abramowitz J, Birnbaumer L, Sham JS: Classical transient receptor potential 1 and 6 contribute to hypoxic pulmonary hypertension through differential regulation of pulmonary vascular functions. Hypertension. 2014;63:173-180(IF:7.63)

5.  Xia Y, Fu Z, Hu J, Huang C, Paudel O, Cai S, Liedtke W, Sham JS: TRPV4 channel contributes to serotonin-induced pulmonary vasoconstriction and the enhanced vascular reactivity in chronic hypoxic pulmonary hypertension. American journal of physiology Cell physiology 2013, 305(7):C704-C715. (IF:3.67)

6.  Xia Y, Wang KP: Transbronchial needle aspiration: where are we now? Journal of thoracic disease. 2013, 5, 678-82. (IF:2.36)

7.  Xia Y, Ma Y, Arias S, Lee H, Wang KP: Utilization of the International Association for the Study of Lung Cancer and Wang’s nodal map for the identification of mediastinum and hilar lymph nodes. Thoracic cancer. 2015 Jul;6(4):464-8. (IF:1.85)

8.  Xia Y, Li W, Shen H: Anti-IgE therapy as novel target for asthma-COPD overlap syndrome: More questions before celebration.  J Asthma. 2017 Mar;54(2):113. (IF:1.12)

9.  Xia Y, Zhang B, Zhang H, Li W, Wang KP, Shen H: Evaluation of lymph node metastasis in lung cancer: who is the chief justice? Journal of thoracic disease. 2015 Dec;7(Suppl 4):S231-7. (IF:2.36)

10.  Xia Y, Cao Y, Xia L, Li W, Shen H: Severe asthma and Asthma-COPD Overlap: A Double Agent or Identical Twins? Journal of thoracic disease. (Accepted)(IF:2.36)

11.  Xia Y, Liang Z, Fu Z, Liu L, Paudel O, Cai S: Clinical management of acute interstitial pneumonia: a case report. Case reports in pulmonology 2012, 2012:678249.

12.  Xia Y, Ying Y, Wang S, Li W, Shen H: Effectiveness of Lung Ultrasonography for the Diagnosis

of Pneumonia in Adults: Review of the Literature and Meta-Analysis. Journal of thoracic disease.

2016 Oct;8(10):2822-2831. (IF:2.36)

13.  Sun H, Xia Y, Paudel O, Yang XR, Sham JS: Chronic hypoxia-induced upregulation of Ca2+-activated Cl- channel in pulmonary arterial myocytes: a mechanism contributing to enhanced vasoreactivity. The Journal of physiology 2012, 590(Pt 15):3507-3521. (IF:4.54)

14.  Jiang YL, Lin AH, Xia Y, Lee S, Paudel O, Sun H, Yang XR, Ran P, Sham JS: Nicotinic acid adenine dinucleotide phosphate (NAADP) activates global and heterogeneous local Ca2+ signals from NAADP- and ryanodine receptor-gated Ca2+ stores in pulmonary arterial myocytes. The Journal of biological chemistry 2013, 288(15):10381-10394. (IF:4.60)

15.  Liu QH, Ben SQ, Xia Y, Wang KP, Huang HD: Evolution of transbronchial needle aspiration technique. J Thorac Dis. 2015 Dec;7(Suppl 4):S224-30. (IF:2.36)

16.  Zhang D, Peng C, Zhao H, Xia Y, Zhang D, Dong H, Song J, Zhou L, Cai S, Zou F: Induction of thymic stromal lymphopoietin expression in 16-HBE human bronchial epithelial cells by 25-hydroxyvitamin D3 and 1,25-dihydroxyvitamin D3. International journal of molecular medicine 2013, 32(1):203-210. (IF:1.88)

17.  Liang Z, Liu L, Zhao H, Xia Y, Zhang W, Ye Y, Jiang M, Cai S. A Systemic Inflammatory Endotype of Asthma with More Severe Disease Identified by Unbiased Clustering of the Serum Cytokine Profile. Medicine (Baltimore). 2016 Jun;95(25):e3774. (IF:5.72)

18.  Lyu Y, Zhao H, Ye Y, Liu L, Zhu S, Xia Y, et al. Decreased soluble RAGE in neutrophilic asthma is correlated with disease severity and RAGE G82S variants. Molecular Medicine Reports. 2018;17(3):4131-7. (IF:1.69)

19.  Liang Z, Zhao H, Lv Y, Li R, Dong H, Liu L, Xia Y, Hou C, Cai S, Zou F: Moderate accuracy of peripheral eosinophil count for predicting eosinophilic phenotype in steroid-naive non-atopic adult asthmatics. Internal medicine 2012, 51(7):717-722. (IF:0.96)

 

会议论文:

1.  Xia Y, Xiao-Ru Y, Omkar P, Zhenzhen F, Shaoxi C, Lutz B, James SKS: Direct evidence for the contribution of TRPC1 and TRPC6 to the development of hypoxic pulmonary hypertension from TRPC knockout mice. In: C63 EXPERIMENTAL MODELS OF PULMONARY VASCULAR DISEASE I. American Journal of Respiratory and Critical Care Medicine; 2013: A4633-A4633. (IF:13.11)

2.  Xia Y, Yang X-R, Paudel O, Fu Z, Birnbaumer L, Sham JSK: TRPC1 and TRPC6 Regulate Chronic Hypoxia-induced Vascular Tone, Vasoreactivity and Pulmonary Hypertension. The FASEB Journal 2013, 27:1140.1149. (IF:5.29)

3. Sun H, Xia Y, Paudel O, Yang X-R, Sham JS: Upregulation of TMEM16A Underlies Chronic Hypoxia-induced Increase of Ca2+-activated Cl- Current in Pulmonary Arterial Smooth Muscle. The FASEB Journal 2012, 26:700.704. (IF:5.29)

4.  Jiang Y-L, Lin AHY, Lee S, Xia Y, Sham JSK: Characterization of NAADP-Induced Global and Local Calcium Signals in Rat Pulmonary Arterial Smooth Muscle Cells. The FASEB Journal 2012, 26:871.873. (IF:5.29)