移动站  | 2017年09月25日 星期一
用户登录

当前位置:首页 >> 师资队伍

基本信息:

姓名: 余红
职务:
职称: 主任医师
学历:
专业:
所属院系: 浙医二院
研究方向: 干细胞治疗心血管疾病;干细胞动员,迁移,归巢和分化机制,及其在心肌修复中的作用;衰老对干细胞生物活性及其促血管新生能力的影响;干细胞分泌的外泌体exosome对心血管病的影响,血管钙化的防。
电话: 0571-87783992
信箱: yuvascular@163.com
个人主页:

个人简介:

浙江大学求是特聘教授,浙江省“千人计划”特聘专家,美国心脏协会会士(Fellow of AHA)。 

长期从事心血管生物学的研究,在干细胞治疗心血管疾病、及衰老对干细胞活性的影响等领域有深入的研究和积极的贡献。在高质量的杂志上发表了70多篇论文以及6部书籍的章节。2011年回国后,已成功申请和参与了国家科技部973项目及重大科学研究计划项目和国家自然科学基金面上项目。 

主要研究方向:干细胞治疗心血管疾病;干细胞动员,迁移,归巢和分化机制,及其在心肌修复中的作用;衰老对干细胞生物活性及其促血管新生能力的影响;干细胞分泌的外泌体exosome对心血管病的影响,血管钙化的防。

学习和工作经历

1978—1982     上海复旦大学生物系           本科

1987—1993      美国南加州大学                  博士研究生

1997 —2002  美国南加州大学医学院          助理教授

2003 —2011    美国迈阿密大学医学院        副教授

2011—现在       浙江大学求是特聘教授,     浙江省“千人计划”专家

近期发表的代表性论文

1.Yu H, K Lu, JY Zhu, JA Wang. Stem Cell Therapy for Ischemic Heart Disease. British Medical Bulletin. 2017 Feb 06 , 121 (1): 135-154. DOI: 10.1093/bmb/ldw059

2.Wang C, H Chen, W Zhu, MF Liu, YC Xu, LL Zhu, F Yang, L Zhang, XB Liu, Z Zhong, J Zhao, J Jiang, M Xiang, Yu H, X Hu, H Lu, and JA Wang*. Nicotine Accelerates Atherosclerosis in Apolipoprotein E-deficient Mice by Activating α7 Nicotinic Acetylcholine Receptor on Mast Cells。Arteriosclero Thromb Vasc Biol. 2017 Jan; 37(1):53-65.

3.Ma Q, X Xia, Q Tao, K Lu, J Shen, Q Xu, X Hu, Y Tang, NL Block, KA Webster, AV Schally, Wang J, H Yu*. Profound actions of an agonist of growth hormone releasing hormone on angiogenic therapy by mesenchymal stem cells. Arteriosclero Thromb Vasc Biol. 2016;36:663-672.

4.Hu X, Y Xu, ZW Zhong, Y Wu, J Zhao, Y Wang, HF Cheng, MJ Kong, FJ Zhang, Q Chen, JZ Sun, Q Li, J Jin, QJ Li, LH Chen, C Wang, HW Zhan, Y Fan, Q Yang, L Yu, RR Wu, J Liang, JY Zhu, Y Wang, YP Jin, YF Lin, F Yang, LL Jian, W Zhu, JH Chen, H Yu, JY Zhang, J Wang. A Large-scale Investigation of Hypoxia-preconditioned Allogeneic Mesenchymal Stem Cells for Myocardial Repair in Non-human Primates: Paracrine Activity Without Remuscularization.  Circ Res. 2016.118(6):970-83. 

5.Xia XY, Q Tao, Q Ma, H Chen, JA Wang, and Yu H*. Growth Hormone-Releasing Hormone and Its Analogues: Significance for MSCs-Mediated Angiogenesis, Stem Cells Int. 2016 Oct 20, Volume 2016 Article ID 8737589.

6.Yang ZX, Wang YZ, Jia BB, Mao GX, Lv YD, Wang GF, Yu H*. Down-regulation of miR-146a,COX-2 and AGEs in simvastatin treated elder patients with hyperlipidemia Geriatrics & Gerontology International 2016; 16:322-328. doi: 10.1111/ggi.12472.

7.Yu H, K Lu, JA Wang. Treatment of heart failure after myocardial infarction with bone marrow-derived mesenchymal stem cells (Review). Cardiol Plus. 2015 Sept; 1(1) 17-23.

8.Hu X, L Zhang, J Jin, W Zhu, Y Xu, Y Wu, Y Wang, H Chen, KA.Webster, H Chen, H Yu, J Wang. Heparanase released from mesenchymal stem cells activates intergrin beta1/HIF-2alpha/Flk-1 signaling and promotes endothelial cell migration and angiogenesis. Stem Cells. 2015, Jun;33(6):1850-62.

9.X Hu, R Wu, Z Jiang, L Wang, P Chen, L Zhang, L Yang, Y Wu, H Chen, H Chen, Y Xu, Y Zhou, X Huang, KA Webster, H Yu*, JA Wang* . Leptin signaling is required for augmented therapeutic properties of mesenchymal stem cells conferred by hypoxia preconditioning. Stem Cells, July 3, 2014; 32:2702–2713

10.MS Zhou, A Wang, H Yu. Link between Insulin Resistance and Hypertension: What is the Evidence from Evolutionary Biology? Diabetology & Metabolic Syndrome. 2014 Jan 31,6:12. 1-8. doi:10.1186/1758-5996-6-12.

11.Z Zhang, J Wang, Y Xu, Z Jiang, R Wu, L Wang, P Chen, X Hu, H Yu. Menstrual blood derived mesenchymal cells ameliorate cardiac fibrosis via inhibition of endothelial to mesenchymal transition in myocardial infarction.  Intl J Cardiol 2013 Sep 30;168(2):1711-4. doi: 10.1016/j.ijcard.2013.03.126.

12.Xu Q, Wang JA, He J, Zhou MS, Adi J, Webster K, Yu H.* Impaired CXCR4 Expression and Cell Engraftment of Bone Marrow-derived Cells from Aged Atherogenic Mice. Atherosclerosis. 219:92-99,  2011

13.Shao H, Xu Q, Wu Q, Ma Q, Slgueiro L, Wang JA, Eton D, Webster K, Yu H.* Defective CXCR4 Expression in Aged Bone Marrow Cells Impairs Vascular Regeneration. J Cell Mol Med. 15(10):2046-2056, 2011。

14.Eton D, Yu H. Enhanced Cell Therapy Strategy to Treat Chronic Limb Threatening Ischemia.J Vasc Surg. 52(1):199-204; 2010 doi:10.1016/j.jvs.2009.12.048 (IF 3.772)

15.Wu Q., Shao H, D. Eton, J Li. B Yang, M. G. Uberti, KA Webster, H. Yu* Extracellular calcium increases CXCR4 Expression on Bone Marrow-derived Cells and Enhances Pro-Angiogenesis Therapy.  J Cell Mol Med. 13(9B):3764-3773.2009.

16.Shao H, Tan, Y, D. Eton, Z. Yang, M. G. Uberti, S Li, A. Schulick, H. Yu* Statin and Stromal Cell Derived Factor-1 Additively Promote Angiogenesis by Enhancement of Progenitor Cells Incorporation into New Vessels. Stem Cells. 26(5):1376-1384, 2008。