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基本信息:

姓名: Stijn van der Veen
职务: 微生物学教授
职称: 教授
学历: 博士
专业: 医学微生物
所属院系: 基础医学系
研究方向: 医学微生物学、宿主与微生物的相互作用和疫苗开发;分子微生物、生物膜的形成和应激反应
电话: 0571-88206684
信箱: stijnvanderveen@zju.edu.cn
个人主页:

个人简介:

教育工作简历
20146-至今: 微生物学教授就职于: 浙江大学医学院基础医学系
20116-2014.5: 博士后就职于: Sir William Dunn School of Pathology/威廉邓恩爵士病理学学院 University of Oxford/牛津大学
2011.1-2011.6: 讲师就职于: Laboratory of Food Microbiology /食品微生物实验室 Wageningen University/瓦赫宁根大学
2008.7-2011.5: 博士后就职于: Laboratory of Food Microbiology/食品微生物实验室 Wageningen University/瓦赫宁根大学
2004.6-2008.6: 博士生就职于: Laboratory of Food Microbiology/食品微生物实验室 Wageningen University/瓦赫宁根大学
1997.9-2004.2: 生物处理技术,本科及硕士学习;瓦赫宁根大学;荷兰硕士论文实践基地: - 微生物系, University of Otago/奥塔戈大学, 新西兰(6个月) - 分子微生物系, RIKILT, 荷兰 (7个月) - 病毒学实验室, Wageningen University/瓦赫宁根大学, 荷兰 (9个月)
项目经费主管单位: 国家自然科学基金委员会课题名称:一种新型淋球菌表面表达抗原介导的保护性免疫应答极化的研究主管单位: 浙江省自然科学基金委员会课题名称:淋病奈瑟菌耐药性分子流行病及抗性机理的研究主管单位: 浙江省自然科学基金委员会课题名称:淋病奈瑟菌耐药性分子流行病及抗性机理的研究主管单位: 浙江省卫生和计划生育委员会课题名称:淋病奈瑟菌治疗性疫苗免疫效应评价及临床前研究主管单位: 中央高校基本科研业务费专项资金课题名称: 多重耐药运输系统Mtr对淋球菌定植宿主并存活的作用研究主管单位: Action Medical Research 课题名称: Improving immunogenicity and coverage of next generation of meningococcal vaccines
学术论文 2015年:
1. Xue, J., Ni, C., Zhou, H., Zhang, C., Van der Veen, S. Incidence of high-level azithromycin-resistant Neisseria gonorrhoeae isolates in China (2015). Journal of Antimicrobial Chemotherapy (doi:10.1093/jac/dkv266)
2. Van der Veen, S., Tang, C.M. The BER necessities: the repair of DNA damage in human-adapted bacterial pathogens (2015). Nature Reviews Microbiology 2: 83-94
3. Van der Veen, S., Nady, N., Franssen, M.C.R, Zuilhof, H., Boom, R.M, Abee, T., Schroen, K. Listeria monocytogenes repellence by enzymatically modified PES surfaces (2015). Journal of Applied Polymer Science 41576: 1-6 2014:
4. Van der Veen, S., Johnson, S., Jongerius, I.,Malik, T., Genovese, A., Santini, L., Staunton, D., Pickering, M., Lea, S.M., Tang, C.M. Non-functional variant 3 factor H binding proteins as meningococcal vaccine candidates (2014). Infection and Immunity 82: 1157-1163
5. Faleri, A., Santini, L., Brier, S., Pansegrau, W., Lo Surdo, P., Scarselli, M., Buricchi, F., Volpini, G., Genovese, A., Van der Veen, S., Lea, S.M., Tang, C.M., Savino, S., Pizza, M., Finco, O., Norais, N., Masignani, V. Two cross-reactive monoclonal antibodies recognize overlapping epitopes on Neisseria meningitidis Factor H binding protein but have different functional properties (2014). Faseb journal 28: 1644-1653 2013:
6. Malito, E., Faleri, A., Lo Surdo, P., Veggi, D., Maruggi, G., Grassi, E., Cartocci, E., Bertoldi, I., Genovese, A., Santini, L., Romagnoli, G., Borgogni, E., Brier, S., Lo Passo, C., Domina, M., Castellino, F., Felici, F., Van der Veen, S., Johnson, S., Lea, S.M., Tang, C.M., Pizza, M., Savino, S., Norais, N., Rappuoli, R., Bottomley, M.J., Masignani, V. Defining a protective epitope on factor H binding protein, a key meningococcal virulence factor and vaccine antigen (2013). Proceedings of the National Academy of Sciences of the United States of America 110: 3304-3309
7. Kadam, S.R., Den Besten, H.M.W., Van der Veen, S., Zwietering, M.H., Moezelaar, R., Abee, T. Diversity assessment of Listeria monocytogenes biofilm formation: impact of growth condition, serotype and strain origin (2013). International Journal of Food Microbiology 165: 259-264 2012:
8. Johnson, S., Tan, L., Van der Veen, S.*, Caesar, J., Goicoechea De Jorge, E., Everett, R., Bai, X., Exley, R.M., Ward, P.N., Ruivo, N., Trivedi, K., Cumber, E., Jones, R., Newham, L., Staunton, D., Borrow, R., Pickering, M., Lea, S.M., Tang, C.M. Design and evaluation of meningococcal vaccines through structure-based modification of host and pathogen molecules (2012). PLoS Pathogens 8: e1002981 *Joint first author
9. Piet, J.R., Brouwer, M.C., Exley, R.M., Van der Veen, S., Van de Beek, D., Van der Ende, A. Meningococcal Factor H binding protein fHbpD184 polymorphism influences clinical course of meningococcal meningitis (2012). PLoS ONE 7: e47973
10. Watanabe, M., Van der Veen, S., Nakajima, H., Abee, T. Effect of respiration and manganese on oxidative stress resistance of Lactobacillus plantarum WCFS1 (2012). Microbiology 158: 293-300
11. Castelijn, G.A., Van der Veen, S., Zwietering, M.H., Moezelaar, R., Abee, T. Diversity in biofilm formation and production of curli fimbriae and cellulose of Salmonella Typhimurium strains of different origin in high and low nutrient medium (2012). Biofouling 28: 51-63
12. Nielsen, P.K., Andersen, A.Z., Mols, M., Van der Veen, S., Abee, T., Kallipolitis, B.H. Genome-wide transcriptional profiling of the cell envelope stress response and the role of LisRK and CesRK in Listeria monocytogenes (2012). Microbiology 158: 963-974
13. Watanabe, M., Van der Veen, S., Abee, T. Impact of respiration on resistance of Lactobacillus plantarum WCFS1 to acid stress (2012). Applied and Environmental Microbiology 78: 4062-4064
14. Nyati, H., Beumer, R., Van der Veen, S., Hazeleger, W., Abee, T. Influence of organic material and biofilms on disinfectant efficacy against Listeria monocytogenes (2012). International Journal of Food Studies 1: 76-84 2011:
15. †Van der Veen, S., Abee, T. Generation of variants in Listeria monocytogenes continuous-flow biofilms is dependent on radical-induced DNA damage and RecA-mediated repair (2011). PLoS ONE 6: e28590
16. Van der Veen, S., Abee, T. Mixed species biofilms of Listeria monocytogenes and Lactobacillus plantarum show enhanced resistance to benzalkonium chloride and peracetic acid (2011). International Journal of Food Microbiology 144: 421-431
17. Abee, T., Kovács, A.T., Kuipers, O.P., Van der Veen, S. Biofilm formation and dispersal in Gram-positive bacteria (2011). Current Opinion in Biotechnology 22: 172-179
18. Van der Veen, S., Abee, T. Bacterial SOS response: a food safety perspective (2011). Current Opinion in Biotechnology 22: 136-142
19. Van der Veen, S., Abee, T. Contribution of Listeria monocytogenes RecA to acid and bile survival and invasion of human intestinal Caco-2 cells (2011). International Journal of Medical Microbiology 301: 334-340 2010:
20. Van der Veen, S., Van Schalkwijk, S., De Vos, W.M., Abee, T., Wells-Bennik, M.H.J. The SOS response of Listeria monocytogenes is involved in stress resistance and mutagenesis (2010). Microbiology 156: 374-384
21. Van der Veen, S., Abee, T. Dependence of continuous flow biofilm formation by Listeria monocytogenes EGD-e on SOS response factor YneA (2010). Applied and Environmental Microbiology 76: 1992-1995
22. Van der Veen, S., Abee, T. HrcA and DnaK are important for static and continuous flow biofilm formation and disinfectant resistance of Listeria monocytogenes (2010). Microbiology 156: 3782-3790
23. Van der Veen, S., Abee, T. SigB is important for Listeria monocytogenes static and continuous flow biofilm formation and disinfectant resistance (2010). Applied and Environmental Microbiology 76: 7854-7860 2009:
24. Van der Veen, S., Abee, T., De Vos, W.M., Wells-Bennik, M.H.J. Genome-wide screen for Listeria monocytogenes genes important for growth at high temperatures (2009). FEMS Microbiology Letters 295: 195-202
25. Van der Veen, S., Wagendorp, A., Abee, T., Wells-Bennik, M.H.J. Diversity assessment of heat resistance of Listeria monocytogenes strains in a continuous-flow heating system (2009). Journal of Food Protection 72: 999-1004 2008:
26. Van der Veen, S., Moezelaar, R., Abee, T., Wells-Bennik, M.H.J. The growth limits of a large number of Listeria monocytogenes strains at combinations of stresses show serotype- and niche-specific traits (2008). Journal of Applied Microbiology 105: 1246-1258 2007:
27. Van der Veen, S., Hain, T., Wouters, J.A., Hossain, H., De Vos, W.M., Abee, T., Chakraborty, T., Wells-Bennik, M.H.J. 2007. The heat-shock response of Listeria monocytogenes comprises genes involved in heat shock, cell division, cell wall synthesis, and the SOS response (2007). Microbiology 153: 3593–3607