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基本信息:

姓名: 胡少华
职务:
职称: 副主任医师
学历: 博士
专业: 神病学
所属院系: 浙医一院
研究方向:
电话:
信箱:
个人主页: http://mypage.zju.edu.cn/hushaohua

个人简介:

胡少华,男,医学博士,副教授,副主任医师,硕士生导师

■  浙江大学医学院附属第一医院精神卫生科副主任

■  浙江省支撑学科——精神病与精神卫生学后备学科带头人

■  浙江大学医学院精神病学教研室副主任

■  中华医学会精神医学分会青年委员会委员(第六届)

■  中华医学会心身医学分会焦虑及相关障碍协作学组委员

■  中华医学会行为医学分会行为医学教育学组委员

■  中国医疗保健国际交流促进会精神卫生分会委员

■  浙江省医学会精神医学分会委员

■  浙江省医学会精神医学分会青年委员会副主任委员(第一届)

■  浙江省神经科学会神经修复与康复学会常务委员

■  浙江省医学会医学鉴定专家

中华精神科杂志Cereb CortexAm J Neuroradiol, Neuroimag Ann Gen Psychiatry审稿专家;国际精神病学杂志编委,

 2008年至美国加州大学洛杉矶分校(UCLA)进修;2012年至美国哥伦比亚大学医学院精神科进行研究访问。主持国家自然基金2项,浙江省自然科学基金1项,浙江省公益技术应用项目1项,浙江省卫生厅课题3项,教育厅项目1项,主参973课题子课题、国家支撑计划子课题、公益性行业科研专项、浙江省自然基金项目共5项,近年共发表论文共40余篇,SCI收录25篇 (第一或通讯作者16篇)。参编《精神病学(案例版)》等教材2本、软件著作权1项。“男性性取向的遗传学和影像学研究”项目作为第二完成人荣获浙江省科技成果三等奖1项,浙江省医药卫生科技奖二等奖1项。

主要研究方向为双相障碍的神经生物学机制、同性恋的生物学机制。临床擅长情感障碍、精神分裂症、性心理障碍的诊治。

发表论文:( * 通讯作者)

Wu W, Zheng YL,Tian LP, Lai JB, Hu CC, Zhang P, Chen JK, Hu JB, Huang ML,  Wei N, Xu WJ, Zhou WH, Lu SJ, Lu J, Qi HL, Wang DD, Zhou XY, Duan JF, Xu Y, Hu SH*. Circulating T lymphocyte subsets, cytokines, and immune checkpoint inhibitors in patients with bipolar II or major depression: a preliminary study. Scientific Reports. 2017; 7: 40530

Huang M, Lu S, Yu L, Li L, Zhang P, Hu J, Zhou W, Hu S, Wei N, Huang J, Weng J, Xu Y. Altered fractional amplitude of low frequency fluctuation associated with cognitive dysfunction in first-episode drug-naive major depressive disorder patients. BMC Psychiatry. 2017; 17(1): 11

Lai JB, Lu QQ, Zhang P, Xu TT, Xu Y, Hu SH*. Aripiprazole augmentation in managing comorbid obsessive-compulsive disorder and bipolar disorder: A case with suicidal attempts. Neuropsychiatr Dis Treat. 2017; 13: 87-90

Lu S, Gao W, Wei Z, Wang D, Hu S, Huang M, Xu Y, Li L. Intrinsic brain abnormalities in young healthy adults with childhood trauma: A resting-state functional magnetic resonance imaging study of regional homogeneity and functional connectivity. Aust N Z J Psychiatry. 2016 Set 30. Pii: 0004867416671415

Hu SH, Lai JB, Xu DR, Qi HL, Peterson BS, Bao AM, Hu CC, Huang ML, Chen JK, Wei N, Hu JB, Li SL, Zhou WH, Xu WJ, Xu Y. Efficacy of repetitive transcranial magnetic stimulation with quetiapine in treating bipolar II depression: a randomized, double-blinded, control study. Scientific Reports. 2016; 6:30537  DOI: 10.1038/srep30537

Wang L, Lai J, Huang J, Hu S*. Possible sertraline-induced extrapyramidal adverse effects in an adolescent. Neuropsychiatr Dis Treat. 2016; 12: 1127-1129

Xu W, Wei N, Xu Y, Hu S*. Does amantadine induce acute psychosis? A case report and literature review. Neuropsychiatr Dis Treat. 2016; 12: 781-783

Lai J, Lu Q, Xu Y, Hu S*. Severe water intoxication and secondary depressive syndrome in relation to delusional infestation. Neuropsychiatr Dis Treat. 2016; 12: 517-521

Lai JXu DPeterson BSXu YWei NZhang MHu S*. Reversible Fluoxetine- Induced Hyperthyroidism: A Case Report. Clin Neuropharmacol. 2016; 39(1): 60-1.

Huang JXu DPeterson BSHu JCao LWei NZhang YXu WXu YHu S*. Affective reactions differ between Chinese and American healthy young adults: a cross-cultural study using the international affective picture system. BMC Psychiatry. 2015; 15: 60  doi:10.1186/s12888-015-0442-9

Zhou W, Huang M, Wei N, Hu S, Wei E, Xu Y. Application of the capture-Recapture  Method in Estimating the Size of the Active Homosexual Male Population in Hangzhou City of China. Asia Pac J Public Health. 2015 Mar;27(2): NP2423-32. 

Wei N, Lai J, Xu D, Qi H, Wang Q, Zhang M, Huang M, Xu Y, Hu S*. Is ecstasy-induced protracted symptom of motion perception associated with altered regional homogeneity of brain? Chinese Med J. 2014; 127(17):3189-91.

Hu S, Xu D, Peterson BS, Wang Q, Lai J, Hu J, Wei N, Zhang M, Xu Y. Differing default mode network activities in men with homosexual or heterosexual preferences. J Sex Med. 2014; 11(10):2474-84. 

Hu S, Yao M, Peterson BS, Xu D, Hu J, Tang J, Fan B, Liao Z, Yuan T, Li Y, Yue W, Wei N, Zhou W, Huang M, Xu Y. A randomized, 12-week study of the effects of extended-release paliperidone (paliperidone ER) and olanzapine on metabolic profile, weight, insulin resistance, and beta-cell function in schizophrenic patients. Psychopharmacology. 2013; 230(1): 3-13.

Hu S, Xu D, Peterson B, Wang Q, He X, Hu J, Xu X, Wei N, Long D, Huang M, Zhou W, Xu W, Zhang M, Xu Y. Association of Cerebral Networks in Resting State with Sexual Preference of Homosexual Men: A Study of Regional Homogeneity and Functional Connectivity. PLoS ONE. 2013; 8(3): e59426

Feng Z, Huang J, Xu Y, Zhang M, Hu S*. Dissociative disorder induced by clarithromycin combined with rabeprazole in a patient with gastritis. J Int Med Res. 2013 Feb;41(1):239-43.

Hu JB, Zhou WH, Hu SH, Huang ML, Wei N, Qi HL, Huang JW, Xu Y. Cross-cultural difference and validation of the Chinese version of Montreal Cognitive Assessment in older adults residing in Eastern China: Preliminary findings.Arch Gerontol Geriatr. 2013; 56(1): 38-43.

Huang ML, Luo BY, Hu JB, Wei N, Chen L, Wang SS, Zhou WH, Hu SH, Xu Y. Combination of citalopram plus paliperidone is better than citalopram alone in the treatment of somatoform disorder: results of a 6-week randomized study. Int Clin Psychopharm. 2012 May; 27(3): 151-8.

Huang ML, Luo BY, Hu JB, Wang SS, Zhou WH, Wei N, Hu SH, Xu Y. Repetitive transcranial magnetic stimulation in combination with citalopram in young patients with first-episode major depressive disorder: a double-blind, randomized, sham-controlled trial. Aust N Z J Psychiatry. 2012 Mar;46(3):257-64.

Hu SH, Wang SS, Zhang MM, Wang JW, Hu JB, Huang ML, Wei N, Zhou WH, Qi HL, Xu WJ, Xu Y. Repetitive transcranial magnetic stimulation-induced seizure of a patient with adolescent-onset depression: a case report and literature review. J Int Med Res. 2011;39(5):2039-44.

Liao ZL, Hu SHXu Y. A case report on the relationship between treatment-resistant childhood-onset schizophrenia and an abnormally enlarged cavum septum pellucidum combined with cavum vergae. Chinese Med J. 2011;125(7):1349-51

Hu SH, Wang QD, Xu Y, Xu LJ, Liao ZL, Xu XJ, Wei EQ, Yan LQ, Hu JB, Wei N, Zhou WH, Huang ML, Zhang MM. Haemodynamic Brain Response to Visual Sexual Stimuli is Different between Homosexual and Heterosexual Men. J Int Med Res. 2011,39(1): 199-211

Zhang M, Hu S, Xu L, Wang Q, Xu X, Wei E, Yan L, Hu J, Wei N, Zhou W, Huang M, Xu Y. Neural circuits of disgust induced by sexual stimuli in homosexual and heterosexual men: An fMRI study. Eur J Radiol. 2011; 80: 418-425

Ruan LM, Hu SH, Huang ML, Hu JB, Cai W. Efficacy and safety of long-actting risperidone on early onset schizophrenia in adoescent patients. Afr J Pharm Pharmacol. 2010; 4(5): 184-92.

Hu SH, Wei N, Wang QD, Yan LQ, Wei EQ, Zhang MM, Hu JB, Huang ML, Zhou WH, Xu Y. Patterns of brain activation during visually evoked sexual arousal differ between homosexual and heterosexual men. Am J Neuroradiol. 2008 Nov;29(10):1890-6.

戚洪莉,胡少华,魏宁,胡婵婵,陈京凯,许毅.双相障碍II型抑郁发作患者神经认知功能损害的研究[J].浙江医学,2016; 38(9): 633-635, 638.

黄满丽, 陈京凯, 叶于富, 许毅, 胡少华, 胡健波, 周韦华, 魏宁, 戚洪莉, 许委娟. 首发精神分裂症患者调节性T细胞及相关细胞因子变化. 浙江医学.2015, 37(14): 5-8

魏宁, 周韦华胡健波黄满丽戚洪莉胡少华张颖然廖峥娈许毅.汶川地震外转伤员心理创伤状况调查分析 中华预防医学杂志,200943(5):376-379IM收录)

胡少华,许毅,李鹏,汪启东,胡健波,魏宁,张敏鸣. 男性同性恋与男性异性恋对厌恶情绪调节模式的差异. 浙江大学学报(医学版).2008375):487-493.  (IM 收录)

胡少华,许毅. 灾难后心理危机干预. 中华预防医学杂志. 2008; 42(11): 782-785. (IM收录)

胡健波,黄满丽,黄文武,胡少华,魏 宁,周韦华,许 . 心理健康自评问卷在汶川地震受灾人群中应用的信效度分析. 中华预防医学杂志,20084211:810-813IM收录)

周韦华,胡健波,胡少华,魏宁,黄满丽,许毅. 三维筛选评估模型在汶川地震外转伤员及家属心理健康状况评估中的应用. 中华预防医学杂志,20084211:798-801IM收录)

魏宁,胡健波,许毅,胡少华*. 浙江省公职人员心理健康状况调查. 浙江医学.2007; 29(6): 529-531 (*通讯作者)

胡少华.抑郁障碍的社会经济负担及对策.中华预防医学杂志.2005; 39(4): 283-284. (IM收录)

胡少华,魏宁等.中国和美国健康成人情感反应差异的跨文化研究.中国临床心理学杂志. 2005; 13(30): 265-267.

胡少华,魏宁,许毅.赛庚啶治疗抑郁药所致的性功能障碍2.浙江医学,2005274):304

许毅,施卫星,胡少华. 杭州男性同性恋浮现率调查. 中华预防医学杂志,2004385):313-315IM收录)

许毅,施卫星,胡少华.杭州市男性同性恋者性行为与艾滋病知识知晓率调查.中华预防医学. 2005; 39(1): 37-39.(IM收录)

许毅,胡少华. 利培酮对N-甲基-D-门冬氨酸诱导的大鼠皮层神经细胞损伤保护作用的研究.中华精神科杂志. 2004; (7):  245-246.

胡少华,许毅.过量服奥氮平抢救成功一例.中华精神科杂志,2003362):119     

会议论文:

1. S-H Hu, M-M Zhang, L-J Xu, N-W Wei, J-B Hu, Yi Xu. Neural Correlates of Disgust Induced by Sexual Stimuli in Homosexual and Heterosexual men: a fMRI study. NeuroImage. Volume 47, Supplement 1, July 2009, Page S190 Organization for Human Brain Mapping 2009 Annual Meeting

2. S-H Hu. Hemodynamic brain response to visual sexual stimulis differnt between homosexual and heterosexual men. 19th European Congress of Psychiatry, 2011

3. S-H Hu. Treatment-resistant childhood-onset schizophrenia and abnormal enlarged cavum septum pellucidum combined with cavum vergae: case report and literature review. 19th European Congress of Psychiatry, 2011

4. Hu SH. A randomized, 12-week study of the effects of extended-release paliperidone (paliperidone ER) and olanzapine on metabolic profile, weight, insulin resistance and β-cell function in schizophrenic patients. 166th APA annual meeting, 2013

5. Hu SH. Association of Cerebral Networks in Resting State with Sexual Preference of Homosexual Men: A Study of Regional Homogeneity and Functional Connectivity. 166th APA annual meeting, 2013.

6. Shaohua Hu, Dongrong Xu, Bradley S Peterson, Qidong Wang, Xiaofu He, Jianbo        Hu, Ning Wei, Minming Zhang, Xiaojun Xu, Manli Huang, Weihua Zhou, Weijuan Xu, Chanchan Hu, Yi Xu. Differing default mode network activities in men with homosexual or heterosexual preferences. 22th annual meeting of Europen Congress of Psychiatry. 1-4 March 2014. Munich,  Germany.

7. Hu S, Xu D, Peterson BS, Wang Q, Lai J, Hu J, Wei N, Zhang M, Xu Y. Differing  default mode network activities in men with homosexual or heterosexual preferences. APA annual meeting, 2014.

8. Hu S, Lai JB, Qi HL, Hu CC, Hu CC, Xu Y. A preliminary evaluation of the efficacy of repetitive TMS in treating a depressive episode in bipolar II disorder. ISBD annual meeting, Canada, 3-6 June, 2015.


专著:

  许毅主编. 精神病学(案例版),胡少华:人格障碍与性心理障碍,科学出版社,45万,2013.6 (ISBN:9787030379214)

 

课题:

1. 胡少华,许毅,魏宁,胡健波,蔡巍. 中国情感图片系统的创建及应用. 浙江省卫生厅(2006A042. 2006. 7-2008.12,经费2

2. 许毅,胡少华,魏宁,蔡巍,胡健波,谭云飞,郭文滔. 重复经颅磁刺激对抑郁症患者血小板5-羟色胺的影响. 浙江省卫生厅. 2006.7-2008.12, 立项

3. 胡少华,胡健波,杨虹,魏宁,石其昌,周韦华,黄满丽,许委娟. 抑郁症患者情绪认知加工障碍的神经机制研究. 浙江省卫生厅(2008B053). 2008.7-2010.12,立项

4. 胡健波,胡少华,周韦华,戚洪莉,魏宁,许委娟,张颖然. 蒙特利尔认知评估量表的中文版编制及在轻度认知功能缺损中初步应用. 浙江省卫生厅. 2008B0912008.6-2010.12,立项

5. 许毅,胡少华. 男性同性恋大脑性活动相关的脑区及神经回路的研究. 中国科学院自动化研究所模式识别国家重点实验室. 2009.1-2010.12,经费8

6. 刘靖,许毅,郭延庆,王力芳,胡少华,张敏鸣等. 人类异常亲和行为的医学遗传学研究. 973子课题. 2010.1-2014.12  (编号:2010CB833905),经费209.4

7. 许毅,胡少华,黄满丽,魏宁,胡健波,周韦华. 精神分裂症、青少年情绪与自杀问题的预警和综合防治及时的研发、转化与应用. 公益性行业科研专项(201002003. 2010.7-2013.6,经费67

8. 胡少华,许毅,黄满丽,魏宁,周韦华. 新型抗抑郁剂联合经颅磁刺激治疗抑郁症优化方案的建立. 浙江省教育厅(Y201019141). 2010.10-2012.10,经费1

9. 黄满丽,胡少华,王爽. 抑郁症患者认知加工障碍的神经机制研究. 浙江省科学技术厅重点科技创新项目子项目(2010R50049, 2011.1-2014.12,  经费:10

10. 胡少华,许毅,商德胜,魏宁,胡健波,黄满丽,周韦华,许委娟,段金凤. 男性同性恋性活动相关的神经回路的影像学研究. 国家自然青年基金(81101013. 2012.1-2014.12,经费23

11. 胡志英,胡少华,方马荣,吴林珍,赵剑虹,姚守珍,丁晓辉,阳洋,李卫云. 产后抑郁症中脑5-羟色胺能神经环路变化的分子机制. 国家自然科学基金面上项目(81371493.2014.1-2018.12, 经费70

12. 胡少华,来建波,汪启东,魏宁,胡健波,黄满丽,周韦华,许委娟,段金凤. 神经性厌食症患者情绪调节环路的脑影像学研究. 浙江省医药卫生平台研究计划重点项目(2014ZDA008). 2014.7-2016.12,经费5

13. 胡少华,汪启东,许毅,胡健波,魏宁,许委娟,吕文. 男性同性恋伴发抑郁症患者大脑结构及神经环路的磁共振成像研究. 浙江省自然科学基金. LY14H1800022014.1-2016.12,经费9.5

14. 胡少华,黄满丽,魏宁,胡健波,路静,陈京凯, 周韦华,许委娟,来建波,段金凤,牟婷婷. 催产素对男性性取向影响的研究. 浙江省公益技术研究社会发展项目 2015C331332015.7-2017.12,经费15

15. 许毅,黄满丽,胡少华,胡健波,王金辉,路静,魏宁,方马荣,许委娟,潘奋,谢健,钱敏才,叶敏捷,胡珍玉,竺可青,陆邵佳. 重大精神障碍诊断相关指标的发现和技术研究. 浙江省科技厅重大科技专项(2015C030402016.1-2019.12,经费100

16. 胡少华,季公俊,路静,陆邵佳,高维佳,胡健波,魏宁,许委娟,来建波,陆巧巧. FMR1NB基因多态性和男性同性恋杏仁核结构和功能的相关性研究. 国家自然科学基金(816763572017.1.-2020.12 直接经费57


专利

计算机软件著作权:谢天胜,何哲浩,胡少华,许毅. 基于webCaps在线图片测试平台软件 V1.0 (登记号:2009SR10760


获奖:

2005年浙江大学优秀教师奖

许毅,胡少华,黄满丽,胡健波,汪启动,张敏鸣,许委娟,胡婵婵,戚洪莉,陈京凯,魏宁,周韦华,杨虹. 男性性取向的遗传学和影像学研究. 浙江省医药卫生科技二等奖(16024). 2016.4.1