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基本信息:

姓名: 周权
职务: 药剂科副主任
职称: 主任药师
学历: 博士
专业: 药理学
所属院系: 浙医二院
研究方向: 1.药物代谢动力学 2.临床药学
电话: 87784615
信箱: zhouquan142602@zju.edu.cn
个人主页:

个人简介:

周权,浙医二院药剂科副主任,长年从事医院药学工作,有丰富的临床药学经验,善于从临床药学实践中捕捉科研信息。擅长药物治疗管理、药动学相互作用和药物基因组学个体化用药研究。具有宽广的学术视野和学术知名度。主持国家自然科学基金项目1项,省级课题十余项,参编12部著作,主编1部,副主编一部,发表论文一百余篇,其中SCI收录30余篇。
(一)近五年发表的中文刊物
1.叶蓁,周权(通讯作者).反相高效液相色谱法测定人血浆中非索非那定浓度.中国现代应用药学杂志,2012,7月11日
2.叶蓁,朱玲玲,周权(通讯作者). 利用体内探针法考察植物药和天然产物对人体细胞色素P450和P-糖蛋白活性的影响。中国现代应用药学杂志
2012年6月
3.何巍,朱玲玲,周权(通讯作者),颜小锋.药师在肠内肠外营养支持中的作用及干预实例.中国现代应用药学杂志,2012年6月
4.严磊,寿军,周权(通讯作者),王华芬.交叉过敏的临床药学干预.中国现代应用药学杂志,2012年10月
5.胡豪,朱玲玲,徐领城,周权(通讯作者). 综合性医院三种肠道清洁剂的药物利用调查.中国现代应用药学杂志,2012年已录用并排版
6.朱玲玲;丁国英;刘长生;周权(通讯作者).1例超高龄卧床鼻饲患者3种药品不良反应的药学监护.药物流行病学杂志,2012年8月
7.周权,朱玲玲.基于优质护理服务药事管理实践.中国卫生质量管理杂志,2012年6月
8. 屈伯宣,田野,余露山,蒋惠娣,周权(通讯作者),曾苏.体外细胞模型中氟伐他汀对映体的手性分离和含量测定方法学研究. 浙江大学学报医学版,2011年第1期
9. 王欧明,周权(通讯作者), 徐领城,金岩,颜小锋。杭州地区调脂药物的应用调研。中国现代应用药学杂志,2010年第10期
10. 汪红芳,朱玲玲,寿军,周权(通讯作者).临床护理中三种静脉给药方式分析.护士进修杂志,2010年第18期
11.朱波英,周权(通讯作者).综合性医院药品通用名后缀的调查分析。中国现代应用药学杂志,2010年第1期
12.朱波英,周权(通讯作者).莫西沙星制剂药品说明书以外用法的临床研究进展。中国药房,2009年11月
13. 王欧明,周权(通讯作者),蒋鸿雁,颜小锋.综合性医院门诊抗高血压药的药物利用研究.中国现代应用药学杂志,2009年10月
14.何巍,张仲苗,周权(通讯作者),张美芳.静脉用药调配中抗肿瘤药物不合理应用分析.中国现代应用药学杂志,2009年第3期
15. 楼洪刚,许东航,袁虹,江波,周权,张仲苗,阮邹荣.多潘立酮咀嚼片的人体药动学和生物等效性.中国药学杂志,2009年
16.吴芳,周权(通讯作者). 我院2002年与2006年抗抑郁药应用的对比.中国医院药学杂志,2008-08-30
17.蒋鸿雁,周权(通讯作者). 综合性医院门诊患者口服质子泵抑制剂的回顾性处方点评. 中国现代应用药学,2008-08-28
18.阮邹荣,周权, 袁虹,江波,许东航,楼洪刚.氟氯西林钠胶囊在中国人体的药动学和生物等效性评价.中国药学杂志,2008-05-08
19. 周权,张仲苗, 周宏民,宋继芬.2种他汀类药物代谢性相互作用处方分析.中国药学杂志,2008-01-22
20. 周权,郑水根,颜小锋,楼洪刚.综合性医院门诊患者克拉霉素的处方点评.中国医院药学杂志,2008,1月
21.颜小锋,周权. 临床药师在新药引进和临床应用评价中应注意的问题。中华医院管理杂志,2007年第12期
22.周权,颜小锋.建立院内药物警戒制度的实践.中华医学院管理杂志,2008年第2期
23.周权,李天元,颜小锋,徐翔,楼洪刚.建立处方点评质量管理制度的实践.中华医学院管理杂志,2008年第8期.
24.张丽,周权.奥卡西平致严重药疹反应1例.天津药学,2007
25.张仲苗,周权. 铜绿假单胞菌注射液对K562细胞株处理后淋巴细胞凋亡及免疫功能的影响,中国药学杂志,2007
26. 江波,许东航, 袁虹, 周权,阮邹荣.左氧氟沙星人体内外相关性研究.中国药学杂志,2007
27.江波,袁虹,许东航,周权,阮邹荣.液相色谱-电喷雾串联质谱法测定人血浆中辛伐他汀浓度,2007
(二)近年来SCI和IM收录论文
Dr. Quan Zhou’s international articles (SCI) during 2000~2013
Li W, Wang XD, Zhou Q (corresponding author). Interventions to improve the quality of antibacterial prescribing for outpatients in a academic medical center hospital during the journey to JCI accreditation. Ther Clin Risk Manag, under peer review.
Xu HM, CAI HW, Dai HB, Yan XF, Zhou Q, Xu G, Huang ZQ, Mao W. Use of Evidence-Based Pharmacotherapy for Secondary Prevention of Coronary Heart Disease: Traditional Chinese Medical Hospital Versus General Hospital. Chinese Journal of Integrative Medicine, 2013, finally accepted.
Li W, Zhu LL, Zhou Q (corresponding author). Pharmacokinetic drug interaction profile of omeprazole with adverse consequences and clinical risk management. Ther Clin Risk Manag, Sent to Typesetting
Zhu LL, Zhou Q (corresponding author). Intervention for improving the appropriateness of physician orders for oral medications in geriatric VIP patients during the journey to JCI accreditation. Ther Clin Risk Manag, editing enquiry proof with author.
Zhu LL, Zhou Q (corresponding author). Therapeutic concerns when oral medications are administered nasogastrically. J Clin Pharm Ther. 2013 Apr 19. doi: 10.1111/jcpt.12041edit.
Zhou Q, Chen QX, Ruan ZR, Yuan H, Xu HM, Zeng S. CYP2C9*3(1075A > C), ABCB1 and SLCO1B1 genetic polymorphisms and gender are determinants of inter-subject variability in pitavastatin pharmacokinetics. Pharmazie. 2013 Mar;68(3):187-94.
Zhu LL, Song P, Zhou Q (corresponding author). A pragmatic approach to beta-lactam use in patients with penicillin allergy. Allergy Asthma Proc. 2013 Mar-Apr;34(2):193.
Yu L, Shi D, Ma L,Zhou Q, Zeng S. Influence of CYP2C8 polymorphisms on the
hydroxylation metabolism of paclitaxel, repaglinide, and ibuprofen enantiomers in vitro. Biopharm Drug Dispos. 2013 Mar 27.
Zhou Q, Ruan ZR, Yuan H, Xu DH, Zeng S. ABCB1 gene polymorphisms, ABCB1 haplotypes and ABCG2 c.421c > A are determinants of inter-subject variability in rosuvastatin pharmacokinetics. Pharmazie. 2013 Feb;68(2):129-34.
Zhou Q, Ruan ZR, Jiang B, Yuan H, Zeng S. Simvastatin pharmacokinetics in healthy Chinese subjects and its relations with CYP2C9, CYP3A5, ABCB1, ABCG2 and SLCO1B1 polymorphisms. Pharmazie. 2013 Feb;68(2):124-8.
Li W, Zhu LL, Zhou Q (corresponding author). Safe medication use based on knowledge of information about contraindications concerning cross allergy and comprehensive clinical intervention. Ther Clin Risk Manag. 2013;9:65-72.
Zhou Q (corresponding author), Ye Z, Ruan Z, Zeng S. Investigation on modulation of human P-gp by multiple doses of Radix Astragali extract granules using fexofenadine as a phenotyping probe. J Ethnopharmacol. 2013 Apr 19;146(3):744-9.
Zhu XP, Zhu LL, Zhou Q (corresponding author). Prescribing practice and evaluation of appropriateness of enteral nutrition in a university teaching hospital. Ther Clin Risk Manag. 2013;9:37-43.
Yu-Wen H, Mei-Bian Z, Xiang X, Xiao-Hua X, Zhou Q, Le J. Socioeconomic Inequality in the Use of Rituximab Therapy Among Non-Hodgkin Lymphoma Patients in Chinese Public Hospitals. Asia Pac J Public Health. 2012 Nov 15.
Zhu LL, Xu LC, Wang HQ, Jin JF, Wang HF, Zhou Q (corresponding author). Appropriateness of administration of nasogastric medication and preliminary intervention. Ther Clin Risk Manag. 2012;8:393-401.
Xu HM, Chen Y, Xu J, Zhou Q (corresponding author). Drug-induced liver injury in hospitalized patients with notably elevated alanine aminotransferase. World J Gastroenterol. 2012 Nov 7;18(41):5972-8.
Chen QX, Hu HH, Zhou Q, Yu AM, Zeng S. An overview of ABC and SLC drug transporter gene regulation. Curr Drug Metab. 2013 Feb;14(2):253-64.
Zhou Q, Ruan ZR, Yuan H, Zeng S. CYP2C9*3(1075A>C), MDR1 G2677T/A and MDR1 C3435T are determinants of inter-subject variability in fluvastatin pharmacokinetics in healthy Chinese volunteers. Arzneimittelforschung. 2012 Nov;62(11):519-24.
Zhu LL, Xu LC, Chen Y, Zhou Q (corresponding author), Zeng S. Poor awareness of preventing aspirin-induced gastrointestinal injury with combined protective medications. World J Gastroenterol. 2012 Jun 28;18(24):3167-72.
Li L, Hu H, Xu S, Zhou Q, Zeng S. Roles of UDP-glucuronosyltransferases in phytochemical metabolism of herbal medicines and the associated herb-drug interactions. Curr Drug Metab. 2012 Jun 1;13(5):615-23.
Huang YW, Jian L, Zhang MB, Zhou Q, Yan XF, Hua XD, Zhou Y, He JL. An investigation of oxidative DNA damage in pharmacy technicians exposed to antineoplastic drugs in two Chinese hospitals using the urinary 8-OHdG assay. Biomed Environ Sci. 2012 Feb;25(1):109-16.
Qu BX, Tian Y, Yu LS, Jiang HD, Zhou Q (corresponding author), Zeng S. [Chiral separation of fluvastatin enantiomers with in vitro cellular method]. Zhejiang Da Xue Xue Bao Yi Xue Ban. 2011 Jan;40(1):12-6.
Zhou Q (corresponding author), Zhu LL, Yan XF, Pan WS, Zeng S. Drug utilization of clarithromycin for gastrointestinal disease treatment. World J Gastroenterol. 2008 Oct 21;14(39):6065-71.
Zhu LL, Zhou Q (corresponding author), Yan XF, Zeng S. Optimal time to take once-daily oral medications in clinical practice. Int J Clin Pract. 2008 Oct;62(10):1560-71.
Xu DH, Lou HG, Yuan H, Jiang B, Zhou Q, Zhang ZM, Ruan ZR(corresponding author). Quantitative determination of domperidone in human plasma by ultraperformance liquid chromatography with electrospray ionization tandem mass spectrometry. Biomed Chromatogr. 2008 Apr;22(4):433-40.
Zhou Q (corresponding author), Yan XF, Pan WS, Zeng S. Is the required therapeutic effect always achieved by racemic switch of proton-pump inhibitors?World J Gastroenterol. 2008 Apr 28;14(16):2617-9.
Lou HG, Ruan ZR(corresponding author), Yuan H, Jiang B, Zhou Q. LC Determination and Bioequivalence Study of Pantoprazole in Human Plasma. Chromatographia, 2008, Published online: 26 February
Zhou Q (corresponding author), Yan XF, Zhang ZM, Pan WS, Zeng S. Rational prescription of drugs within similar therapeutic or structural class for gastrointestinal disease treatment: drug metabolism and its related interactions. World J Gastroenterol. 2007 Nov 14;13(42):5618-28.
Zhou Q, Ruan Z, Yuan H, Jiang B, Xu D. RP-HPLC analysis of flucloxacillin in human plasma: validation and application to a bioequivalence study. Pharmazie. 2007 Feb;62(2):101-4.
Xu DH, Ruan ZR, Zhou Q, Yuan H, Jiang B. Quantitative determination of rosuvastatin in human plasma by liquid chromatography with electrospray ionization tandem mass spectrometry. Rapid Commun Mass Spectrom. 2006;20(16):2369-75.
Zhou Q (corresponding author), Ruan ZR, Yuan H, Jiang B, Xu DH. Pharmacokinetics and bioequivalence of ranitidine and bismuth derived from two compound preparations. World J Gastroenterol. 2006 May 7;12(17):2742-8.
Zhou Q (corresponding author), Ruan ZR, Drug utilization study of 2 statins in outpatients from a perspective of metabolic drug-drug interactions. Acta Pharmacol Sin, 2006, 27(Suppl 1): 206.
Zhou Q, Ruan ZR(corresponding author), Yuan H, Jiang B. Determination of penciclovir in human plasma using liquid chromatography with fluorescence detection: Application to a bioequivalence study. Chromatographia, 2006, 64(9-10):571-5.
Zhang ZM, Zheng XX, Jiang B, Zhou Q. [Effects of L-tetrahydropalmatine on concentrations of neurotransmitter amino acids in mice with cerebral ischemia]. Zhongguo Zhong Yao Za Zhi. 2004 Apr;29(4):371-3.
Zhou Q, Yao TW, Yu YN, Zeng S. Concentration dependent stereoselectivity of propafenone N-depropylation metabolism with human hepatic recombinant CYP1A2. Pharmazie. 2003 Sep;58(9):651-3.
Yan XF, Zhou Q, Yao TW, Zeng S, Yao HP, Yu YN. [Stereoselective determination of propranolol enantiomer in transgenic cell lines expressing human cytochrome P450]. Zhejiang Da Xue Xue Bao Yi Xue Ban. 2003 Apr;32(2):116-20.
Zhou Q, Yao TW, Zeng S. Chiral reversed phase high-performance liquid chromatography for determining propranolol enantiomers in transgenic Chinese hamster CHL cell lines expressing human cytochrome P450. J Biochem Biophys Methods. 2002 Dec 31;54(1-3):369-76.
Zhou Q, Yao TW, Zeng S. Effects of stereochemical aspects on drug interaction in pharmacokinetics. Acta Pharmacol Sin. 2002 May;23(5):385-92.
Zhou Q, Yao TW, Zeng S. Chiral metabolism of propafenone in rat hepatic microsomes treated with two inducers. World J Gastroenterol. 2001 Dec;7(6):830-5.
Zhou Q, Yao TW, Yu YN, Zeng S. Stereoselective metabolism of propafenone by human liver CYP3A4 expressed in transgenic Chinese hamster CHL cells lines. Acta Pharmacol Sin. 2001 Oct;22(10):944-8.
Yao TW, Zhou Q, Zeng S. Stereoselective determination of propafenone enantiomers in transgenic Chinese hamster CHL cells expressing human cytochrome P450. Biomed Chromatogr. 2000 Nov;14(7):498-501.
(三)近三年代表著作
1. 药物代谢学 卫生部“十一五”规划教材 2008年8月 浙江大学出版社 第一副主编
2. 药物代谢与转运及其临床意义. 见蒋学华主编, 《临床药动学》,普通高等教育“十一五”国家级规划教材 2007年7月 高等教育出版社
3. 临床药物代谢动力学与药物相互作用. 见曾苏主编,《临床药物代谢动力学》,卫生部“十一五”规划教材 2007年7月 人民卫生出版社
4. 药物治疗学. 见赵光云主编. 《执业药师继续教育-培训教材(二)》,2008年4月 浙江科技出版社
5. 手性药物分析,见姚彤炜主编 《手性药物分析》,人民卫生出版社,2008年10月
6. 药物流行病学;药物信息学. 见赵光云主编. 《执业药师继续教育-培训教材(四)》,2010年4月 浙江科技出版社
7. 临床药理学. 见赵光云主编. 《执业药师继续教育-培训教材(三)》,2009年4月 浙江科技出版社
8. 周权主编. 调脂药物的合理应用.人民卫生出版社. 2011年,
9.编委.PBL学习方法在药学服务中的应用。见赵光云主编. 《执业药师继续教育-培训教材》,2011年4月,浙江科技出版社