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基本信息:

姓名: 郑敏
职务: 医学院皮肤学科点负责人
职称: 教授
学历: 博士
专业: 皮肤病与性病学
所属院系: 浙医二院
研究方向: 变态反应性炎症性自身免疫性皮肤病
电话: 87784558
信箱: minz@zju.edu.cn
个人主页: www.dermanet.cn

个人简介:

姓名:郑敏
性别: 男
籍贯: 浙江
最后学历:博士研究生
简历:
1978.2-1982.12浙江医科大学医疗系本科毕业,获学士学位;
1985.9-1988.9浙江医科大学附属二院皮肤病学硕士研究生毕业,获硕士学位;
1988.9-1990.9浙江医科大学附属二院皮肤科住院医师;
1990.9-1996.12浙江医科大学附属二院皮肤科主治医师;
1993.3-1996.1德国基尔大学医学院皮肤病医院研究生获博士学位;
1996.12-1999.12浙江医科大学附属二院皮肤科主任,副教授;
1999.12-现在 浙江大学医学院附属二院皮肤科主任,教授;硕导
2000.12-现在 浙江大学医学院博导,主任医师
2012.7-现在 国家临床重点专科建设项目皮肤科主任

所属学科: 皮肤性病科
职称:教授、主任医师、博导、硕导
现任职务:
国家临床重点专科建设项目皮肤科主任;
浙江大学医学院皮肤性病学学科点负责人;
浙江大学医学院附属二院皮肤科主任,教研室主任。



学术团体和社会兼职:
国际银屑病网络(Psoriasis International Network)科学委员会委员,中国联络员;
美国实验皮肤病学会(Society for Investigative Dermatology)资深会员;
欧洲皮肤性病学会(European Academy of Dermato-Venereology)会员
亚洲皮肤病学会(Asian Academy of Dermato-Venereology)理事
中华医学会皮肤科学会副主任委员,全国常委;
中华医学会皮肤科学会银屑病学组组长
中国医师协会皮肤科分会全国常委;
浙江省医学会理事会理事;
浙江省医学会皮肤科学会主任委员;
浙江省抗癌协会医用激光专业委员会副主任委员;
浙江省麻风防治协会常任理事;
浙江省性病爱滋病防治协会常任理事;

杂志编委:
《World Journal of Dermatology 》编委2012-
《中华皮肤科杂志》编委; 1998-
《临床皮肤科杂志》编委; 2003-
《中国皮肤性病杂志》编委;2003-
《中国麻风皮肤病杂志》编委;2003-
《中华性传播感染杂志英文版》编委;2004-
《浙江大学学报医学版》编委; 2000-
《国外医学皮肤病学分册》编委;2000-
《美中皮肤病杂志》编委; 2004-
《浙江创伤杂志》编委;2004-
《皮肤科时讯》编委;2005-
《浙江医学》编委;2007-

国内外专业杂志同行评审专家
《Arch Dermatol Res》1994-
《Chin Med J》2004-
《J Invest Dermatol》2006-
《Clin Exp Dermatol》2006-
《Mol Cell Biochem》2007-
《Tissue Engineering》2007-
《J Cel Mol Med》2008-

近几年发表SCI收录文章,摘要和章节等:
1.W.S.Lee,H.J.Lee,G.S.Choi,W.K.Cheong,S.K.Chow, M.T. Gabriel, K.L. Hau,H.Kang,M.R.Mallari, R.Y.Tsai, J.Zhang, M.Zheng:Guideline for management of androgenetic alopecia based on BASP classification-the Asian consensus committee guideline,JEADV 2013 (in press)
2. Wu XJ, Jing J, Zhu JW, Xue D, Liu H, Böhm M, Lu ZF, Zheng M:Expression and localization of Artemis serine 516 phosphorylation in human scalp skin.Exp Dermatol. 2012 Nov;21(11):881-3. doi: 10.1111/exd.12009.
3.Zhu JW, Wu XJ, Lu ZF, Cai SQ, Zheng M:Purse String Suture for Round and Oval Defects: An Useful Technique in Dermatologic Surgery. J Cutan Med Surg 2012 1(16):11-7
4. Zhu JW, Wu XJ, Luo D,Cai SQ, Zheng M:Activation of VEGFR-2 signaling in response to moderate dose of ultraviolet B promotes survival of normal human keratinocytes. Int J Biochem & Cell Bio 2012(44)246-256
5. Cuicui Liu, Lilla Landeck, Sui-Qing Cai, Zheng M:Majocchi's granuloma over the face. Indian J Dermatol Venereol Leprol. 2012,78(1):113-5
6. Man XY, Zheng M: Generalized deep cutaneous granuloma due to Trichophyton rubum in an immunocompromised patient," JAMA 2012, 307(4):404-405)
7. Zhou J, Man XY, Li Wei, Chen JQ, Cai S, Zheng M: Regulation of Integrin α5 and β4 in Normal and Scleroderma Epidermal Keratinocytes Br J Dermatol. 2012, 166(6):1369-70
8. Chen JQ, Man XY, Zheng M: Asymptomatic Plaques on Toe Web. Asymptomatic Plaques on Toe Web Clinical Infectious Diseases 2012 55: 1164-1165
9. Li W, Man XY, Li CM, Chen JQ, Zhou J, Cai SQ, Lu ZF, Zheng M: VEGF induced proliferation of human hair follicles dermal papilla cells through VEGFR-2-mediated activation of ERK. Exp Cell Res 2012 318(14):1633-40
10. Li W, Lu ZF, Man XY, Li CM, Zhou J, Chen JQ, Yang XH, Wu XiJ, Cai SQ, Zheng M: VEGF upregulates VEGF receiptor-2 on human outer root sheath cells and stimulates proliferation through ERK pathway. Mol Biol Rep 2012 39(9)8687-94
11. Qian H, Zheng M: Prevalence of allergic diseases in China. in Book: Multidisciplinary Approaches to Allergies p1-17 Zhejiang University Press & Springer.2012.Sept
12. Qian H, Zheng M: Diagnosis of skin allergy diseases. in Book: Multidisciplinary Approaches to Allergies p181-191 Zhejiang University Press & Springer.2012.Sept
13. Zhou J, Man XY, Zheng M, Cai SQ: Multiple plexiform schwannoma of a finger. Eur J Dermatol 2012,22(1)149-50
14.Wu XJ, Zhu JW, Liu H,Lu ZF, Zheng M: Expression and Localization of phospho-Artemis (Serine516)in hair follicles during induced growth of mouse hair. Arch Dermatolo Res 2012 304(4):319-24
15. Gao ZS, Yang ZW, Wu SD, Wang HY, Liu ML, Mao WL, Wang J, Gadermaier G, Ferreira F, Zheng M, van Ree R.: Peach allergy in China: A dominant role for mugwort pollen lipid transfer protein as a primary sensitizer. J Allergy Clin Immunol. 2012 Aug 29. [Epub ahead of print]
16.CM. Li, W. Li, XY Man, ZG. Liu and Zheng M: Expression of Pigment Epithelium-Derived Factor in human Cutaneous appendages Clin Exp Dermatol 2012 (in press)
17.Zheng M, Zhu XJ, Song M et al. A randomized, double-blind, placebocontrolled study of ustekinumab in Chinese patients with moderate to severe plaque psoriasis: LOTUS trial results. J Dermatol 2012; 39: 238-9.
18.Zhu JianWei, Min Zheng:Verruous Carcinoma Due to Arsenic ingestion in a psoriasis patient. J Cutan Med Surg 2012, 15 (in press)
19.Li C, Man X, Li W, Zhou J, Chen J, Cai S, Zheng M.: Regulation of adhesion by vascular endothelial growth factor in HaCaT cells. Mol Cell Biochem. 2011,346(1-2):173-8.
20. Li CM, Li W, Man XY, Zhou J, Chen JQ, Cai SQ, Zheng M. Pigment epithelium-derived factor plays an inhibitory role in proliferation and migration of HaCaT cells. Mol Biol Rep. 2011,38(3):2099-105
21. Man XY, Li Wei, Chen Jiaqi, Zhou Jiong, Liao YuanJin, Li Chunming, Cai Suiqing, Zheng M: Huriez syndrome with squamous cell carcinoma Eur J Dermatol 2011,21(2):294-295
22. Wei He, Fei Zhu, Xiaoguang Ma, Xinyu Zhao, Min Zheng, Zhao Chen, Steven B. Heymsfield, Shankuan Zhu: Actinic Skin Damage and Mortality - the First National Health and Nutrition Examination Survey Epidemiologic Follow-up Study. PLoS One. 2011;6 (5):e19907
23. Zheng M: psoriasis in Northeast Asian in Book: Asia skin and skin diseases p59-65 MEDrang Inc.2011.May
24. Capparis spinosa protects against oxidative stress in systemic sclerosis dermal fibroblasts. Arch Dermatol Res. 2010, 302(5):349-55.
25. Expression and localization of vascular endothelial growth factor and vascular endothelial growth factor receptor-2 in human epidermal appendages: a comparison study by immunofluorescence. Clin Exp Dermatol,2009 34(3):396-401
26. Overexpression of VEGFRs on keratinocytes in psoriasis: regulated by calcium independent of VEGF.J Cell Mol Med 2008 ,12.(2):649-660
27. Immunolocalization and expression of vascular endothelial growth factor receptors (VEGFRs) and neuropilins (NRPs) on keratinocytes in human epidermis. Molecular Medicine 2006.12(7-8)127-136
28. Mucinous Eccrine Nevus: A Case Presents Hyperhidrosis. Acta Dermatol-Verneol 2006.86(6)554-555
29. Expression of VEGFR-2 on HaCaT cells is regulated by VEGF and plays an active role in mediating VEGF induced effects. Biochem Biophys Res Commun. 2006 Oct;349(1)31-38.
30. Biological characterization of cultured dermal papilla cells and hair follicle regeneration in vitro and in vivo. Chin Med J (Engl). 2006 Feb 20;119(4):275-81.
31. Overexpression of Phosphorylated-STAT3 Correlated with the Invasion and Metastasis of Cutaneous Squamous Cell Carcinoma. J Dermatol. 2005,32:354-360.
32. [Advances in research on relationship between DNA hypomethylation and systemic lupus erythematosus.] Zhejiang Da Xue Xue Bao Yi Xue Ban. 2006 Jul;35(4):458-62.
33. [Effects of traditional Chinese herbs on growth of mouse hair follicles and hair bulb cells in vitro.] Zhejiang Da Xue Xue Bao Yi Xue Ban. 2006 Jul;35(4):435-9.
34. Zheng M, et al: Expression of vascular endothelium growth factor receptor 3 on keratinocytes in psoriatic epidermis. J Invest Dermatol 2006.125(4) Abstract.
35. Man XY, Zheng M, Yang XH: Calcium enhance mRNA expression of VEGFR1,VEGFR2 and VEGFR3,but not Neuropilins on epidermal keratinocytes. J Invest Dermatol 2006.125(4)Abstract
36. Yang XH, Zheng M, Man SY et al: 17βestradiol enhance the mRNA and protein expression in HaCaT cell line. J Invest Dermatol 2006.125(4)Abstract
37. Cai SQ, Zheng M, et al: Acitretin Induces Apoptosis and Change of Relative Signaling Pathway in Epidermoid Carcinoma Cell Line. J Invest Dermatol 2006.125(4)Abstract
38. Zhou JG, Zheng M, et al: High Mobility Group Box 1 Expression in Murine Lupus Nephritis. J Invest Dermatol 2006.125(4)Abstract
39. Zhang XQ, Zheng M, et al: Effects of 8-methoxypsoralen on melanocytes adhesion, migration and expression of MMP-2 in vitro. J Invest Dermatol 2006.125(4)Abstract
40. Zheng M、Liu Yang, et al: Relationship between Serum level of MDC and MMP-9 and disease activity in patients with SLE.J Invest Dermatol 2006.125(4):Abstract
41.Zheng M et al. Skin-like Structure Generated from Implantation of Hair Follicle Bulb Cells into Collagen/Chitosan Porous Scaffolds in vitro. J Invest Dermatol 2005.124(4):A99 (590)Abstract
42. Zheng M et al. Protective Effects of Minocycline against Hair Follicle Damage Induced by Cytosine Arabinoside. J Invest Dermatol 2005.124(4):A99 (589)Abstract
43. Zheng M, Cai Suiqing, et al. The Effects of Acitretin on proliferation and Apoptosis Induction in Non-Melanoma Epidermal Squamous Carcinoma Cells. J Invest Dermatol 2005.124(4):A17 (100)Abstract
44. Lu Zhongfa, Zheng M et al: Biological Characterizaton ofcultured dermal papilla cells and hair follicle regeneration in vitro and in vivo…J Invest Dermatol 2005.4: 2005.124(4):A100 (595) Abstract
学术活动:
近年来,在美国新奥尔良市、欧洲法国巴黎、奥地利维也纳、韩国首尔和中国北京分别主持了3次国际会议全体会议、6次国际大会的专题讨论会和座谈会,发表了240多篇论文,出版了5本专著,编写教材5册,并注册2项中国专利。
成果奖励:
1.1998年浙江省科学技术进步三等奖(1)
2.1999年国家教育部科学技术进步二等奖(98-208)(1)
3.2002年浙江省科学技术进步三等奖(3)
4.2004年浙江省科学研究进步二等奖(1)
5.2008年浙江省科学技术进步三等奖(2008C13038)(1)

教学课程
1.2005年度校级精品课程 皮肤性病学 编号320
2.2006年度校级优质课程 皮肤性病学 编号146
3.2009年度浙江省级精品课程 皮肤性病学
4.2011年度优秀浙江省级精品课程 皮肤性病学
承担课题
1.银屑病患者的T淋巴细胞化学趋化受体研究. -----------浙江省自然科学基金2000-2002主持
3..银屑病患者的T淋巴细胞化学趋化功能研究.中华医学会皮肤科分会 1996-1998主持
4.皮肤性病学多媒体辅助教学(重点课程建设) 浙江大学1997-2000主持
5.黑色素瘤免疫活性细胞化学趋化细胞因子受体研究. 省卫生厅1998-2000主持
6含毛囊人工皮肤的研制和应用 ----------- 浙江省科技计划重点项目2003-2005主持
7. 银屑病表皮VEGF受体表达和功能研究, 国家自然科学基金30471565 2005-2007主持
8.色素上皮衍生因子在银屑病皮损形成和转归中的作用及其机制研究 国家自然科学基金30771945
2008-2010主持
9.血管内皮细胞生长因子受体特异性拮抗剂治疗银屑病的实验研究 国家自然科学基金30771945
2010-2012主持
10.成功申办 2010年: 德国柏林 “皮肤炎症:临床及相关问题” 研讨会 2010-Dec-5-9 中德科学中心(中国国家自然科学基金会和德国国家研究基金会)双边科学研讨会项目(GZ652)
11.银屑病皮损上皮/内皮-间充质转化及间充质-上皮/内皮转化的研究, 国家自然科学基金81171497 2012-2016主持