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基本信息:

姓名: 李君
职务:
职称: 教授
学历: 博士
专业: 内科学(传染病)
所属院系: 浙医一院
研究方向: 生物人工肝与肝脏组织工程
电话: 87236425
信箱: lijun2009@zju.edu.cn
个人主页: www.junli2000.com

个人简介:

李君,男, 1971年出生,内科学(传染病学)博士,浙江大学教授、博士生导师。现任浙江大学传染病诊治国家重点实验室副主任;中国解剖学会干细胞转化医学分会常委、中华医学会肝病学分会青年委员、中国生物医学工程学会组织工程与再生医学分会青年委员、全国肝衰竭与人工肝专家委员会委员、浙江省医学会肝病委员会青年委员;浙江省新世纪151人才、浙江省“杰出青年基金”获得者;国家自然科学基金、教育部留学回国科研基金和浙江省自然科学基金网评专家。2004年6月至9月在日本岗山大学进行为期3个月的肝细胞移植研究,2006年1月至2008年4月在美国加州大学洛杉矶分校(UCLA)Cedars-Sinai Medical Center做博士后研究。主要研究方向为干细胞与肝脏再生医学治疗重型肝炎研究。
近年来,作为课题负责人主持国家自然科学基金、863和国家科技重大专项子课题等国家级课题8项,部省级课题10余项,发表SCI论文30余篇,以第一或通信作者发表Hepatology (IF 12.003), J Proteome Res (IF 5.056), Stem Cells Dev (IF 4.79),Liver Int (IF 4.412)等SCI论文13篇;获国家科技进步一等奖1项(排名第四),浙江省科技进步奖一等奖2项(排名第二),授权国家发明专利3项,2013年获第七届吴孟超医学青年基金奖。
已发表论文
1)Zhou Q, Li L. Li J*. Stem Cells with Decellularized Liver Scaffolds in Liver Regeneration and Their Potential Clinical Applications. Liver Int. 2014 May 2. doi: 10.1111/liv.12581 (Corresponding author)
2)Li J, Zhang L, Xin J, Jiang L, Li J, Zhang T, Jin L, Li J, Zhou P, Hao S, Cao H, Li L. Immediate intraportal transplantation of human bone marrow mesenchymal stem cells prevents death from fulminant hepatic failure in pigs. Hepatology. 2012;56(3):1044–1052.
3)Li J, Xin J, Hao S, Zhang L, Jiang L, Chen D, Xie Q, Xu W, Cao H, Li L. Return of the metabolic trajectory to the original area after human bone marrow mesenchymal stem cell transplantation for the treatment of fulminant hepatic failure. J Proteome Res. 2012;11(6):3414−3422.
4)Li J, Xin J, Zhang L, Wu J, Jiang L, Zhou Q, Li J, Guo J, Cao H, Li L. Human hepatic progenitor cells express hematopoietic cell markers CD45 and CD109. Int J Med Sci. 2014; 11(1): 65-79.
5)Li J, Xin J, Zhang L, Jiang L, Cao H, Li L. Rapid Detection of rpoB Mutations in Rifampin Resistant M. tuberculosis from Sputum Samples by Denaturing Gradient Gel Electrophoresis. Int J Med Sci. 2012; 9(2):148-156.
6)Tao R, Li J*, Xin J, Wu J, Guo J, Zhang L, Jiang L, Zhang W, Yang Z, Li L. Methylation Profile of Single Hepatocytes Derived from Hepatitis B Virus-Related Hepatocellular Carcinoma. PLoS One. 2011;6(5):e19862.(Co-first author)
7)Li J, Wu W, Xin J, Guo J, Jiang L, Tao R, Cao H, Hong X, Li L. Acute hepatic failure-derived bone marrow mesenchymal stem cells express hepatic progenitor cell genes. Cells Tissues Organs. 2011;194:371-381.
8)Li J, Tao R, Wu W, Cao H, Xin J, Guo J, Jiang L, Hong X, Demetriou AA, Farkas D, Li L. Transcriptional profiling and hepatogenic potential of acute hepatic failure-derived bone marrow mesenchymal stem cells. Differentiation. 2010;80,(2-3):166-174.
9)Li J, Tao R, Wu W, Cao H, Xin J, Li J, Guo J, Jiang L, Gao C, Demetriou AA, Farkas DL, Li L. 3D PLGA scaffolds improve differentiation and function of bone marrow mesenchymal stem cell-derived hepatocytes. Stem Cells Dev. 2010;19(9):1427-36.
10)Sheng J, Li J*, Sheng G, Yu H, Huang H, Cao H, Lu Y, Deng X. Characterization of rpoB Mutations Associated with Rifampin Resistance in Mycobacterium Tuberculosis from Eastern China. J Appl Microbiol. 2008;105(3):904-11. (Corresponding author).
11)Li J, Li L, Yu H, Cao H, Gao C, Gong Y. Growth and Metabolism of Human Hepatocytes on Biomodified Collagen Poly(lactic-co-glycolic acid) Three-Dimensional Scaffold. ASAIO J. 2006;52(3):321-7.
12)Li J, Li LJ, Cao HC, Sheng GP, Yu HY, Xu W, Sheng JF. Establishment of highly differentiated immortalized human hepatocyte line with Simian virus 40 large tumor antigen for liver-based cell therapy. ASAIO J. 2005;51(3):262-8.
13)Jun L*, Jifang S, Miaoquan L, Yingyan L, Xihong X. Effects of Magnolol and Honokiol on the activities of streptococcal glucosyltransferases both in solution and adsorbed on an experimental pellicle. Lett Appl Microbiol. 2004,39(5):459-65. (Corresponding author).