医学博士，教授，博士生导师，皮肤科主任
从事皮肤病与性病学的临床、教学与科研工作数十年。临床工作经验丰富，擅长皮肤病理诊断，对过敏性皮肤病、结缔组织病以及性病尤其是尖锐湿疣诊治和研究有独到之处。曾多次在德国、澳大利亚、美国等著名研究机构进修学习和合作研究，与国外知名学者的良好合作已成功选派多位学生攻博或联合培养博士。入选浙江省政府151人才培养工程和浙江省创世纪卫生人才计划，主要科研工作有：建立了HPV的研究平台和动物模型；构建了HPV－CRT重组DNA疫苗并研究其细胞免疫反应；对HPV11 E7 CTL表位肽的筛选和免疫功能鉴定；siRNA干预技术对HPV6/11的抑制研究；HPV感染与机体免疫的相互作用机制和可能的干预手段；淋病奈瑟氏菌外膜蛋白Porin I蛋白抗体的免疫学研究；蛋白激酶抑制剂对系统性红斑狼疮的治疗作用研究；过敏性皮肤病的屏障功能与发病机制。近年承担项目有：浙江省卫生厅科研基金、浙江省科技开发基金、国家教育部留学启动基金和人事部留学启动基金、国家自然科学基金、浙江省自然基金、教育部重点科技项目、杭州市科技局科研项目、以及国际合作项目。近年发表在国内外刊物的论文30余篇。获国家发明专利二项。
学术团体任职：
中华医学会皮肤病分会全国青年委员、中华医学会变态反应分会全国委员、中国医师协会皮肤科分会委员、浙江省免疫学会肿瘤免疫专业委员会副主任委员、浙江省中西医结合会皮肤美容分会副主委、浙江省医学会皮肤性病分会副主委、中国皮肤科时讯杂志编委、中国皮肤性病学杂志编委
近三年发表论文：
(1) Chen XZ, Zhu KJ, Xu Y, Tang XY, Cai XZ, Zhang X, Cheng H.RNA interference silences the human papillomavirus 6b/11 early gene E7 in vitro and in vivo. Clin Exp Dermato. 2009 Oct 23. [Epub ahead of print]
(2) K-J Zhu, J-P Cen, J-X Lou, Q Wang, X Zhang, Y Xu, X-Z Chen, H Cheng. Imiquimod inhibits the differentiation but enhances the maturation of human monocyte-derived dendritic cells. International Immunopharmacology. Volume 9, Issue 4，April 2009, Pages 412-417
(3) Zhu K, He F, Jin N, Lou J, Cheng H. Complete atrioventricular block associated with dapsone therapy: a rare complication of dapsone-induced hypersensitivity syndrome. Journal of Clinical Pharmacy and Therapeutics (2009) 34, 489–492
(4).Chen XZ, Mao XH, Zhu KJ, Jin N, Ye J, Cen JP, Zhou Q, Cheng H.Toll like receptor agonists augment HPV 11 E7-specific T cell responses by modulating monocyte-derived dendritic cells. Arch Dermatol Res. 2009 Jul 4. [Epub ahead of print]
(5)Y Xu, K-J Zhu, N Zhu, D-H Jiang, X-Z Chen and H Cheng. Expression of Foxp3+CD4+CD25+ regulatory T cells and Th1⁄Th2,Tc1⁄Tc2 profiles in the peripheral blood of patients with condyloma acuminatum. Clinical and Experimental Dermatology. 2009; Mar 34(2) :,229–235 34229-35,
(6)Xu Y, Zhu KJ, Chen XZ, Zhao KJ, Lu ZM, Cheng H. Mapping of cytotoxic T lymphocytes epitopes in E7 antigen of human papillomavirus type 11. Arch Dermatol Res. 2008 Jun;300(5):235-42.
(7)Zhu KJ, Zhou Q, Lin AH, Lu ZM, Cheng H. The use of intravenous immunoglobulin in cutaneous and recurrent perforating intestinal Degos disease (malignant atrophic papulosis). Br J Dermatol. 2007 Jul; 157(1):206-7.
(8)Zhao KJ, Cheng H, Zhu KJ, Xu Y, Chen ML, Zhang X, Song T, Ye J, Wang Q, Chen DF. Recombined DNA vaccines encoding calreticulin linked to HPV6bE7 enhance immune response and inhibit angiogenic activity in B16 melanoma mouse model expressing HPV 6bE7 antigen. Arch Dermatol Res. 2006 Jul;298(2):64-72.
(9) Zhu K, Cheng H, Mao X, et al. Increased endocytic activity in monocyte-derived dendritic cells in patients with psoriasis vulgaris. Indian J Med Res 2006; 123(1):43-50